Homo sapiens (human): 255189 Help Entry 255189            CDS       T01001                                  Symbol PLA2G4F, PLA2G4FZ Name (RefSeq) phospholipase A2 group IVF   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04010   MAPK signaling pathway hsa04014   Ras signaling pathway hsa04072   Phospholipase D signaling pathway hsa04217   Necroptosis hsa04270   Vascular smooth muscle contraction hsa04370   VEGF signaling pathway hsa04611   Platelet activation hsa04664   Fc epsilon RI signaling pathway hsa04666   Fc gamma R-mediated phagocytosis hsa04724   Glutamatergic synapse hsa04726   Serotonergic synapse hsa04730   Long-term depression hsa04750   Inflammatory mediator regulation of TRP channels hsa04912   GnRH signaling pathway hsa04913   Ovarian steroidogenesis hsa04921   Oxytocin signaling pathway hsa05231   Choline metabolism in cancer Network nt06544  Neuroactive ligand signaling   Element N01900   Serotonin-HTR2-GNAQ/11 signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     255189 (PLA2G4F)    00565 Ether lipid metabolism     255189 (PLA2G4F)    00590 Arachidonic acid metabolism     255189 (PLA2G4F)    00591 Linoleic acid metabolism     255189 (PLA2G4F)    00592 alpha-Linolenic acid metabolism     255189 (PLA2G4F)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     255189 (PLA2G4F)    04014 Ras signaling pathway     255189 (PLA2G4F)    04370 VEGF signaling pathway     255189 (PLA2G4F)    04072 Phospholipase D signaling pathway     255189 (PLA2G4F)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     255189 (PLA2G4F)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     255189 (PLA2G4F)    04664 Fc epsilon RI signaling pathway     255189 (PLA2G4F)    04666 Fc gamma R-mediated phagocytosis     255189 (PLA2G4F)   09152 Endocrine system    04912 GnRH signaling pathway     255189 (PLA2G4F)    04913 Ovarian steroidogenesis     255189 (PLA2G4F)    04921 Oxytocin signaling pathway     255189 (PLA2G4F)   09153 Circulatory system    04270 Vascular smooth muscle contraction     255189 (PLA2G4F)   09156 Nervous system    04724 Glutamatergic synapse     255189 (PLA2G4F)    04726 Serotonergic synapse     255189 (PLA2G4F)    04730 Long-term depression     255189 (PLA2G4F)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     255189 (PLA2G4F)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     255189 (PLA2G4F) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      255189 (PLA2G4F) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PLA2_B cPLA2_C2 C2 Motif Other DBs NCBI-GeneID:  255189 NCBI-ProteinID:  NP_998765 HGNC:  27396 Ensembl:  ENSG00000168907 UniProt:  Q68DD2 A5PKZ7 LinkDB All DBs Position 15:complement(42139034..42156636) Genome browser AA seq 849 aa AA seqDB search MLWALWPRWLADKMLPLLGAVLLQKREKRGPLWRHWRRETYPYYDLQVKVLRATNIRGTD LLSKADCYVQLWLPTASPSPAQTRIVANCSDPEWNETFHYQIHGAVKNVLELTLYDKDIL GSDQLSLLLFDLRSLKCGQPHKHTFPLNHQDSQELQVEFVLEKSQVPASEVITNGVLVAH PCLRIQGTLRGDGTAPREEYGSRQLQLAVPGAYEKPQLLPLQPPTEPGLPPTFTFHVNPV LSSRLHVELMELLAAVQSGPSAELEAQTSKLGEGGILLSSLPLGQEEQCSVALGEGQEVA LSMKVEMSSGDLDLRLGFDLSDGEQEFLDRRKQVVSKALQQVLGLSEALDSGQVPVVAVL GSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYRDPAWSQVALQGPIE RAQVHVCSSKMGALSTERLQYYTQELGVRERSGHSVSLIDLWGLLVEYLLYQEENPAKLS DQQEAVRQGQNPYPIYTSVNVRTNLSGEDFAEWCEFTPYEVGFPKYGAYVPTELFGSELF MGRLLQLQPEPRICYLQGMWGSAFATSLDEIFLKTAGSGLSFLEWYRGSVNITDDCQKPQ LHNPSRLRTRLLTPQGPFSQAVLDIFTSRFTSAQSFNFTRGLCLHKDYVAGREFVAWKDT HPDAFPNQLTPMRDCLYLVDGGFAINSPFPLALLPQRAVDLILSFDYSLEAPFEVLKMTE KYCLDRGIPFPSIEVGPEDMEEARECYLFAKAEDPRSPIVLHFPLVNRTFRTHLAPGVER QTAEEKAFGDFVINRPDTPYGMMNFTYEPQDFYRLVALSRYNVLNNVETLKCALQLALDR HQARERAGA NT seq 2550 nt NT seq  +upstreamnt  +downstreamnt atgctttgggcactctggccaaggtggctggcagacaagatgctgcccctcctgggggca gtgctgcttcagaagagagagaagaggggccctctgtggaggcactggcggcgggaaacc tacccatactatgacctccaggtgaaggtgctgagggccacaaacatccggggcacagac ctgctgtccaaagccgactgctatgtgcaactgtggctgcccacggcgtccccaagccct gcccagactaggatagtggccaactgcagtgaccccgagtggaatgagaccttccactac cagatccatggtgctgtgaagaacgtcctggagctcaccctctatgacaaggacatcctg ggcagcgaccagctctctctgctcctgtttgacctgagaagcctcaagtgtggccaacct cacaaacacaccttcccactcaaccaccaggattcacaagagctgcaggtggaatttgtt ctggagaagagccaggtgcctgcatctgaagtcatcaccaacggggttctggtggctcac ccctgtctgagaatccagggcacgctccggggagatgggacagccccacgggaagagtac ggctctaggcagctccagctggcagtgcctggagcctacgagaagccacagctcttgccc ctgcagcctcccacagagccaggcctcccacccacctttaccttccacgtgaacccagtg ctgagctccaggctacacgtggagctgatggagctgctggcagctgtgcagagtggcccc agcgcagagttggaggctcagaccagcaagctgggcgaggggggcatcctgctctcctct ctgcccctaggccaggaggaacagtgttctgtggccctgggggagggccaggaggtggct ctgagcatgaaggtggaaatgagctccggggacctagacctacgccttggctttgacctc tctgacggggagcaggagtttctggacaggaggaagcaggtcgtgtccaaggccctgcag caagtgctgggattgagtgaggctctggacagtggccaggtgcctgtagtggctgtgttg ggttccgggggtggaacccgagccatgtcttctctgtacggcagcctggcagggttgcag gagctcggccttctagacactgtgacctacctgagtggggtctctgggtctacctggtgc atctccacactctacagggacccagcctggtcccaggtggccttgcagggccccattgag cgtgcccaggttcacgtctgcagcagtaagatgggagctttgtccacggagcggctacag tactacactcaggaactgggggtccgggagcgcagtggccacagcgtgtccctcatcgac ctctggggcctccttgttgagtatctcctgtaccaggaggagaaccctgccaagctgtct gaccaacaggaggcggtccgccagggtcagaacccttaccccatttacaccagtgtcaac gtccgcaccaacttgagtggggaagattttgcagagtggtgcgagttcacgccctatgag gttggcttccccaagtacggggcttatgttcccaccgagctcttcggctcagaactcttc atgggacgattgctgcagctccagcctgaaccccggatctgttacctgcaaggtatgtgg ggcagcgcctttgccaccagcctggatgagatcttcctaaagaccgccggctcgggcctc agcttcctggagtggtacagaggcagtgtgaatatcacagacgactgccagaagcctcag ctgcacaacccctcgaggctgcgaacgaggctcctcaccccacaggggcccttctcccag gctgtgctggacatattcacctcccgcttcacttccgcccagagctttaacttcacccgg ggtctctgcttgcacaaggactatgtggctggcagggagttcgtggcctggaaagacaca cacccggacgccttccccaaccagctcacccccatgcgggactgcctgtacctggtggac ggaggctttgccatcaactctccgttcccactggctctgctgcctcagagagcagtggac ctcattctgtcctttgactattccttggaagccccttttgaggtcttgaagatgacagag aagtactgcctggaccgaggaatccccttccctagcatcgaggtgggccctgaggacatg gaggaggcccgtgagtgctatctgtttgccaaggctgaggacccccgctcccccattgtg ctgcacttccccctggttaaccgtaccttccgcacacacctggccccaggtgtggagcga caaacagctgaggagaaggcctttggggactttgtcatcaacaggccagacaccccctat ggcatgatgaacttcacctatgagccccaggacttttatcggctggtggccctcagtcga tacaacgtcctgaacaacgtggagaccttgaagtgcgccctccagctggctctggaccgg caccaggctcgggagagggcaggggcctga

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