KEGG T01001: 257202

Homo sapiens (human): 257202

Entry

257202            CDS       T01001

Symbol

GPX6, GPX5p, GPXP3, GPx-6, GSHPx-6, dJ1186N24, dJ1186N24.1

Name

(RefSeq) glutathione peroxidase 6

K00432

glutathione peroxidase [EC:1.11.1.9]

Organism

hsa Homo sapiens (human)

Pathway

hsa00480

Glutathione metabolism

hsa01100

Metabolic pathways

hsa04918

Thyroid hormone synthesis

hsa05014

Amyotrophic lateral sclerosis

hsa05016

Huntington disease

hsa05022

Pathways of neurodegeneration - multiple diseases

Network

nt06026 Glutathione biosynthesis
nt06525 Ferroptosis

Element

N01589

Glutathione biosynthesis

Brite

KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    257202 (GPX6)
09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    257202 (GPX6)
09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    257202 (GPX6)
   05016 Huntington disease
    257202 (GPX6)
   05022 Pathways of neurodegeneration - multiple diseases
    257202 (GPX6)
Enzymes [BR:hsa01000]
1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.9  glutathione peroxidase
     257202 (GPX6)

SSDB

Motif

Pfam:

GSHPx

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

LinkDB

Position

6:complement(28503296..28515793)

AA seq 221 aa
MFQQFQASCLVLFFLVGFAQQTLKPQNRKVDCNKGVTGTIYEYGALTLNGEEYIQFKQFA
GKHVLFVNVAAYUGLAAQYPELNALQEELKNFGVIVLAFPCNQFGKQEPGTNSEILLGLK
YVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCPPTSDLLGSSSQLFWEPMKVHDIR
WNFEKFLVGPDGVPVMHWFHQAPVSTVKSDILEYLKQFNTH

NT seq 666 nt +upstreamnt +downstreamnt
atgttccagcagttccaggcctcctgtcttgtcctgtttttcctggttggctttgctcag
cagaccctaaagcctcaaaataggaaggtggattgcaacaaaggggtaacaggcaccatc
tatgagtatggagccctcaccctcaacggcgaggagtacatccaattcaagcagtttgca
ggcaagcacgtcctgtttgtcaatgtggccgcctattgaggcttggcagctcagtatcct
gaactgaatgcactacaggaggagctgaagaattttggtgtcattgtgttggcctttccc
tgcaaccagtttggaaaacaagaaccaggaacaaactcagaaatacttcttggtctcaag
tatgtgtgtccaggtagtggctttgtccccagtttccagctctttgagaaaggggatgtg
aatggagaaaaagaacagaaggtctttactttcctgaagaactcctgccctccgacctct
gatcttttgggctcatcaagccaactcttctgggagcccatgaaggtccatgatatccgc
tggaactttgagaaatttctggtggggcccgatggagtccctgtcatgcattggttccac
caggctccagtcagcacagtcaagtcagacatcctggagtacctaaagcagttcaatacc
cactag

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