KEGG   Homo sapiens (human): 25865
Entry
25865             CDS       T01001                                 
Symbol
PRKD2, HSPC187, PKD2, nPKC-D2
Name
(RefSeq) protein kinase D2
  KO
K06070  protein kinase D [EC:2.7.11.13]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04015  Rap1 signaling pathway
hsa04925  Aldosterone synthesis and secretion
hsa05208  Chemical carcinogenesis - reactive oxygen species
Network
nt06223  TNF signaling (cancer)
  Element
N01411  Metals to NFKB signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    25865 (PRKD2)
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    25865 (PRKD2)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    25865 (PRKD2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    25865 (PRKD2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     25865 (PRKD2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  PKD family
   25865 (PRKD2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 ABC1 C1_2 PH Kinase-like Kdo RH_dom Pox_ser-thr_kin
Other DBs
NCBI-GeneID: 25865
NCBI-ProteinID: NP_001073349
OMIM: 607074
HGNC: 17293
Ensembl: ENSG00000105287
Pharos: Q9BZL6(Tchem)
UniProt: Q9BZL6
Structure
LinkDB
Position
19:complement(46674316..46717114)
AA seq 878 aa
MATAPSYPAGLPGSPGPGSPPPPGGLELQSPPPLLPQIPAPGSGVSFHIQIGLTREFVLL
PAASELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSSGDIQEGDL
VEVVLSASATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRC
AFSIPNNCSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSS
SSASSYTGRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKF
NCHKRCATRVPNDCLGEALINGDVPMEEATDFSEADKSALMDESEDSGVIPGSHSENALH
ASEEEEGEGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWR
LDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGE
MPGGTPGGPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQ
ENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVA
ILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILV
ALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAP
EVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGA
IDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQF
AAEHPLPGSGLPTDRDLGGACPPQDHDMQGLAERISVL
NT seq 2637 nt   +upstreamnt  +downstreamnt
atggccaccgccccctcttatcccgccgggctccctggctctcccgggccggggtctcct
ccgccccccggcggcctagagctgcagtcgccgccaccgctactgccccagatcccggcc
ccgggttccggggtctcctttcacatccagatcgggctgacccgcgagttcgtgctgttg
cccgccgcctccgagctggctcatgtgaagcagctggcctgttccatcgtggaccagaag
ttccctgagtgtggcttctacggcctttacgacaagatcctgcttttcaaacatgacccc
acgtcggccaacctcctgcagctggtgcgctcgtccggagacatccaggagggcgacctg
gtggaggtggtgctgtcggcctcggccaccttcgaggacttccagatccgcccgcacgcc
ctcacggtgcactcctatcgggcgcctgccttctgtgatcactgcggggagatgctcttc
ggcctagtgcgccagggcctcaagtgcgatggctgcgggctgaactaccacaagcgctgt
gccttcagcatccccaacaactgtagtggggcccgcaaacggcgcctgtcatccacgtct
ctggccagtggccactcggtgcgcctcggcacctccgagtccctgccctgcacggctgaa
gagctgagccgtagcaccaccgaactcctgcctcgccgtcccccgtcatcctcttcctcc
tcttctgcctcatcgtatacgggccgccccattgagctggacaagatgctgctctccaag
gtcaaggtgccgcacaccttcctcatccacagctatacacggcccaccgtttgccaggct
tgcaagaaactcctcaagggcctcttccggcagggcctgcaatgcaaagactgcaagttt
aactgtcacaaacgctgcgccacccgcgtccctaatgactgcctgggggaggcccttatc
aatggagatgtgccgatggaggaggccaccgatttcagcgaggctgacaagagcgccctc
atggatgagtcagaggactccggtgtcatccctggctcccactcagagaatgcgctccac
gccagtgaggaggaggaaggcgagggaggcaaggcccagagctccctggggtacatcccc
ctaatgagggtggtgcaatcggtgcgacacacgacgcggaaatccagcaccacgctgcgg
gagggttgggtggttcattacagcaacaaggacacgctgagaaagcggcactattggcgc
ctggactgcaagtgtatcacgctcttccagaacaacacgaccaacagatactataaggaa
attccgctgtcagaaatcctcacggtggagtccgcccagaacttcagccttgtgccgccg
ggcaccaacccacactgctttgagatcgtcactgccaatgccacctacttcgtgggcgag
atgcctggcgggactccgggtgggccaagtgggcagggggctgaggccgcccggggctgg
gagacagccatccgccaggccctgatgcccgtcatccttcaggacgcacccagcgcccca
ggccacgcgccccacagacaagcttctctgagcatctctgtgtccaacagtcagatccaa
gagaatgtggacattgccactgtctaccagatcttccctgacgaagtgctgggctcaggg
cagtttggagtggtctatggaggaaaacaccggaagacaggccgggacgtggcagttaag
gtcattgacaaactgcgcttccctaccaagcaggagagccagctccggaatgaagtggcc
attctgcagagcctgcggcatcccgggatcgtgaacctggagtgcatgttcgagacgcct
gagaaagtgtttgtggtgatggagaagctgcatggggacatgttggagatgatcctgtcc
agtgagaagggccggctgcctgagcgcctcaccaagttcctcatcacccagatcctggtg
gctttgagacaccttcacttcaagaacattgtccactgtgacttgaaaccagaaaacgtg
ttgctggcatcagcagacccatttcctcaggtgaagctgtgtgactttggctttgctcgc
atcatcggcgagaagtcgttccgccgctcagtggtgggcacgccggcctacctggcaccc
gaggtgctgctcaaccagggctacaaccgctcgctggacatgtggtcagtgggcgtgatc
atgtacgtcagcctcagcggcaccttccctttcaacgaggatgaggacatcaatgaccag
atccagaacgccgccttcatgtacccggccagcccctggagccacatctcagctggagcc
attgacctcatcaacaacctgctgcaggtgaagatgcgcaaacgctacagcgtggacaaa
tctctcagccacccctggttacaggagtaccagacgtggctggacctccgagagctggag
gggaagatgggagagcgatacatcacgcatgagagtgacgacgcgcgctgggagcagttt
gcagcagagcatccgctgcctgggtctgggctgcccacggacagggatctcggtggggcc
tgtccaccacaggaccacgacatgcaggggctggcggagcgcatcagtgttctctga

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