KEGG   Homo sapiens (human): 25945
Entry
25945             CDS       T01001                                 
Symbol
NECTIN3, CD113, CDW113, NECTIN-3, PPR3, PRR3, PVRL3, PVRR3
Name
(RefSeq) nectin cell adhesion molecule 3
  KO
K06592  poliovirus receptor-related protein 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04514  Cell adhesion molecule (CAM) interaction
hsa04517  IgSF CAM signaling
hsa04520  Adherens junction
Network
nt06546  IgSF CAM signaling
  Element
N01949  NECTIN1 interanctions
N01950  NECTIN2 interactions
N01951  NECTIN3 interactions
N01954  NECL2 interactions
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecule (CAM) interaction
    25945 (NECTIN3)
   04517 IgSF CAM signaling
    25945 (NECTIN3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    25945 (NECTIN3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    25945 (NECTIN3)
   04090 CD molecules [BR:hsa04090]
    25945 (NECTIN3)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  Nectin family
   25945 (NECTIN3)
CD molecules [BR:hsa04090]
 Proteins
  25945 (NECTIN3)
SSDB
Motif
Pfam: C2-set_2 Ig_3 V-set ig I-set Ig_2 Ig_6 TM_ErbB1 Ig_VEGFR-1-like_5th Adeno_E3_CR2 Ig_PVRIG
Other DBs
NCBI-GeneID: 25945
NCBI-ProteinID: NP_056295
OMIM: 607147
HGNC: 17664
Ensembl: ENSG00000177707
UniProt: Q9NQS3
Structure
LinkDB
Position
3:111071816..111194170
AA seq 549 aa
MARTLRPSPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCGALAGPI
IVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGR
VLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDS
LIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFAR
GRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPF
KSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT
TTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVS
VLAGIFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQQDELDSYPDSVKKENKNPVNN
LIRKDYLEEPEKTQWNNVENLNRFERPMDYYEDLKMGMKFVSDEHYDENEDDLVSHVDGS
VISRREWYV
NT seq 1650 nt   +upstreamnt  +downstreamnt
atggcgcggaccctgcggccgtccccgctgtgtcctggaggcggcaaagcacaactttcc
tccgcttctctcctcggagccgggctcctgctgcagcccccgacgccacctccgctgctg
ctgctgctcttcccgctgctgctcttctccaggctctgtggtgccttagctggaccaatt
attgtggagccacatgtcacagcagtatggggaaagaatgtttcattaaagtgtttaatt
gaagtaaatgaaaccataacacagatttcatgggagaagatacatggcaaaagttcacag
actgttgcagttcaccatccccaatatggattctctgttcaaggagaatatcagggaaga
gtcttgtttaaaaattactcacttaatgatgcaacaattactctgcataacataggattc
tctgattctggaaaatacatctgcaaagctgttacattcccgcttggaaatgcccagtcc
tctacaactgtaactgtgttagttgaacccactgtgagcctgataaaagggccagattct
ttaattgatggaggaaatgaaacagtagcagccatttgcatcgcagccactggaaaaccc
gttgcacatattgactgggaaggtgatcttggtgaaatggaatccactacaacttctttt
ccaaatgaaacggcaacgattatcagccagtacaagctatttccaaccagatttgctaga
ggaaggcgaattacttgtgttgtaaaacatccagccttggaaaaggacatccgatactct
ttcatattagacatacagtatgctcctgaagtttcggtaacaggatatgatggaaattgg
tttgtaggaagaaaaggtgttaatctcaaatgtaatgctgatgcaaatccaccacccttc
aaatctgtgtggagcaggttggatggacaatggcctgatggtttattggcttcagacaat
actcttcattttgtccatccattgactttcaattattctggtgtttatatctgtaaagtg
accaattcccttggtcaaagaagtgaccaaaaagtcatctacatttcagatcctcctact
actaccacccttcagcctacaattcagtggcatccctcaactgctgacatcgaggatcta
gcaacagaacctaaaaaattgcccttcccattgtcaactttggcaacaattaaggatgac
acaattgccacgatcattgctagtgtagtgggtggggctctcttcatagtacttgtaagt
gttttggctggaatattctgctataggagaagacggacgtttcgtggagactactttgcc
aagaactacattccaccatcagatatgcaaaaagaatcacaaatagatgttcttcaacaa
gatgagcttgattcttacccagacagtgtaaaaaaagaaaacaaaaatccagtgaacaat
ctaatacgtaaagactatttagaagagcctgaaaaaactcagtggaacaatgtagaaaat
ctcaataggtttgaaagaccaatggattattatgaagatctaaaaatgggaatgaagttt
gtcagtgatgaacattatgatgaaaacgaagatgacttagtttcacatgtagatggttcc
gtaatttccaggagggagtggtatgtttag

KEGG   Homo sapiens (human): 57863
Entry
57863             CDS       T01001                                 
Symbol
CADM3, BIgR, CMT2FF, IGSF4B, NECL1, Necl-1, TSLL1, synCAM3
Name
(RefSeq) cell adhesion molecule 3
  KO
K06780  cell adhesion molecule 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04514  Cell adhesion molecule (CAM) interaction
hsa04517  IgSF CAM signaling
Network
nt06546  IgSF CAM signaling
  Element
N01953  NECL1 interactions
N01954  NECL2 interactions
Disease
H00264  Charcot-Marie-Tooth disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecule (CAM) interaction
    57863 (CADM3)
   04517 IgSF CAM signaling
    57863 (CADM3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    57863 (CADM3)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  Nectin family
   57863 (CADM3)
SSDB
Motif
Pfam: Ig_3 Ig_2 I-set ig C2-set_2 V-set C1-set C2-set_3 Ig_5 Syndecan
Other DBs
NCBI-GeneID: 57863
NCBI-ProteinID: NP_001120645
OMIM: 609743
HGNC: 17601
Ensembl: ENSG00000162706
UniProt: Q8N126
Structure
LinkDB
Position
1:159171615..159203313
AA seq 398 aa
MGAPAASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSL
QWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTA
KSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQ
EDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPD
PPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCT
ATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKG
TYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI
NT seq 1197 nt   +upstreamnt  +downstreamnt
atgggggccccagccgcctcgctcctgctcctgctcctgctgttcgcctgctgctgggcg
cccggcggggccaacctctcccaggacgacagccagccctggacatctgatgaaacagtg
gtggctggtggcaccgtggtgctcaagtgccaagtgaaagatcacgaggactcatccctg
caatggtctaaccctgctcagcagactctctactttggggagaagagagcccttcgagat
aatcgaattcagctggttacctctacgccccacgagctcagcatcagcatcagcaatgtg
gccctggcagacgagggcgagtacacctgctcaatcttcactatgcctgtgcgaactgcc
aagtccctcgtcactgtgctaggaattccacagaagcccatcatcactggttataaatct
tcattacgggaaaaagacacagccaccctaaactgtcagtcttctgggagcaagcctgca
gcccggctcacctggagaaagggtgaccaagaactccacggagaaccaacccgcatacag
gaagatcccaatggtaaaaccttcactgtcagcagctcggtgacattccaggttacccgg
gaggatgatggggcgagcatcgtgtgctctgtgaaccatgaatctctaaagggagctgac
agatccacctctcaacgcattgaagttttatacacaccaactgcgatgattaggccagac
cctccccatcctcgtgagggccagaagctgttgctacactgtgagggtcgcggcaatcca
gtcccccagcagtacctatgggagaaggagggcagtgtgccacccctgaagatgacccag
gagagtgccctgatcttccctttcctcaacaagagtgacagtggcacctacggctgcaca
gccaccagcaacatgggcagctacaaggcctactacaccctcaatgttaatgaccccagt
ccggtgccctcctcctccagcacctaccacgccatcatcggtgggatcgtggctttcatt
gtcttcctgctgctcatcatgctcatcttccttggccactacttgatccggcacaaagga
acctacctgacacatgaggcaaaaggctccgacgatgctccagacgcggacacggccatc
atcaatgcagaaggcgggcagtcaggaggggacgacaagaaggaatatttcatctag

KEGG   Homo sapiens (human): 23705
Entry
23705             CDS       T01001                                 
Symbol
CADM1, BL2, IGSF4, IGSF4A, NECL2, Necl-2, RA175, ST17, SYNCAM, TSLC1, sTSLC-1, sgIGSF, synCAM1
Name
(RefSeq) cell adhesion molecule 1
  KO
K06781  cell adhesion molecule 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04514  Cell adhesion molecule (CAM) interaction
hsa04517  IgSF CAM signaling
Network
nt06546  IgSF CAM signaling
  Element
N01953  NECL1 interactions
N01954  NECL2 interactions
Disease
H00054  Nasopharyngeal cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecule (CAM) interaction
    23705 (CADM1)
   04517 IgSF CAM signaling
    23705 (CADM1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    23705 (CADM1)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  Nectin family
   23705 (CADM1)
SSDB
Motif
Pfam: Ig_3 Ig_2 I-set ig V-set C2-set_2 Ig_C17orf99 C1-set Syndecan
Other DBs
NCBI-GeneID: 23705
NCBI-ProteinID: NP_055148
OMIM: 605686
HGNC: 5951
Ensembl: ENSG00000182985
UniProt: Q9BY67 X5D8W0
Structure
LinkDB
Position
11:complement(115169236..115504415)
AA seq 442 aa
MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA
TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG
RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF
KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ
YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI
NNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITD
SRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADA
DTAIINAEGGQNNSEEKKEYFI
NT seq 1329 nt   +upstreamnt  +downstreamnt
atggcgagtgtagtgctgccgagcggatcccagtgtgcggcggcagcggcggcggcggcg
cctcccgggctccggctccggcttctgctgttgctcttctccgccgcggcactgatcccc
acaggtgatgggcagaatctgtttacgaaagacgtgacagtgatcgagggagaggttgcg
accatcagttgccaagtcaataagagtgacgactctgtgattcagctactgaatcccaac
aggcagaccatttatttcagggacttcaggcctttgaaggacagcaggtttcagttgctg
aatttttctagcagtgaactcaaagtatcattgacaaacgtctcaatttctgatgaagga
agatacttttgccagctctataccgatcccccacaggaaagttacaccaccatcacagtc
ctggtcccaccacgtaatctgatgatcgatatccagaaagacactgcggtggaaggtgag
gagattgaagtcaactgcactgctatggccagcaagccagccacgactatcaggtggttc
aaagggaacacagagctaaaaggcaaatcggaggtggaagagtggtcagacatgtacact
gtgaccagtcagctgatgctgaaggtgcacaaggaggacgatggggtcccagtgatctgc
caggtggagcaccctgcggtcactggaaacctgcagacccagcggtatctagaagtacag
tataagcctcaagtgcacattcagatgacttatcctctacaaggcttaacccgggaaggg
gacgcgcttgagttaacatgtgaagccatcgggaagccccagcctgtgatggtaacttgg
gtgagagtcgatgatgaaatgcctcaacacgccgtactgtctgggcccaacctgttcatc
aataacctaaacaaaacagataatggtacataccgctgtgaagcttcaaacatagtgggg
aaagctcactcggattatatgctgtatgtatacgatccccccacaactatccctcctccc
acaacaaccaccaccaccaccaccaccaccaccaccaccatccttaccatcatcacagat
tcccgagcaggtgaagaaggctcgatcagggcagtggatcatgccgtgatcggtggcgtc
gtggcggtggtggtgttcgccatgctgtgcttgctcatcattctggggcgctattttgcc
agacataaaggtacatacttcactcatgaagccaaaggagccgatgacgcagcagacgca
gacacagctataatcaatgcagaaggaggacagaacaactccgaagaaaagaaagagtac
ttcatctag

KEGG   Homo sapiens (human): 253559
Entry
253559            CDS       T01001                                 
Symbol
CADM2, IGSF4D, NECL3, Necl-3, SynCAM_2, SynCAM-2, synCAM2
Name
(RefSeq) cell adhesion molecule 2
  KO
K06782  cell adhesion molecule 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04517  IgSF CAM signaling
Network
nt06546  IgSF CAM signaling
  Element
N01953  NECL1 interactions
N01954  NECL2 interactions
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    253559 (CADM2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    253559 (CADM2)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  Nectin family
   253559 (CADM2)
SSDB
Motif
Pfam: Ig_3 I-set ig Ig_2 V-set C2-set_2 C1-set Ig_5 Izumo-Ig Ig_6 C2-set_3 T-box_assoc MGC-24 DcuA_DcuB
Other DBs
NCBI-GeneID: 253559
NCBI-ProteinID: NP_001161146
OMIM: 609938
HGNC: 29849
Ensembl: ENSG00000175161
UniProt: Q8N3J6
LinkDB
Position
3:84958989..86074429
AA seq 435 aa
MIWKRSAVLRFYSVCGLLLQGSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPA
QQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTV
LGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRK
TFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQE
GQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATN
TIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNALA
GQNGPDHALIGGIVAVVVFVTLCSIFLLGRYLARHKGTYLTNEAKGAEDAPDADTAIINA
EGSQVNAEEKKEYFI
NT seq 1308 nt   +upstreamnt  +downstreamnt
atgatttggaaacgcagcgccgttctccgcttctacagtgtctgcgggctcctgctacaa
ggcagccaagggcagtttccactaacacagaatgtaaccgttgttgaaggtggaactgca
attttgacctgcagggttgatcaaaatgataacacctccctccagtggtcaaatccagct
caacagactctgtactttgacgacaagaaagctttaagggacaataggatcgagctggtt
cgcgcttcctggcatgaattgagtattagtgtcagtgatgtgtctctctctgatgaagga
cagtacacctgttctttatttacaatgcctgtcaaaacttccaaggcatatctcaccgtt
ctgggtgttcctgaaaagcctcagattagtggattctcatcaccagttatggagggtgac
ttgatgcagctgacttgcaaaacatctggtagtaaacctgcagctgatataagatggttc
aaaaatgacaaagagattaaagatgtaaaatatttaaaagaagaggatgcaaatcgcaag
acattcactgtcagcagcacactggacttccgagtggaccggagtgatgatggagtggcg
gtcatctgcagagtagatcacgaatccctcaatgccacccctcaggtagccatgcaggtg
ctagaaatacactatacaccatcagttaagattataccatcgactccttttccacaagaa
ggacagcctttaattttgacttgtgaatccaaaggaaaaccactgccagaacctgttttg
tggacaaaggatggcggagaattaccagatcctgaccgaatggttgtgagtggtagggag
ctaaacattcttttcctgaacaaaacggataatggtacatatcgatgtgaagccacaaac
accattggccaaagcagtgcggaatatgttctcattgtgcatgatgttcccaacactttg
cttcccactactatcatcccctcccttaccactgcaacagtcacaaccactgtagccata
acaaccagcccaaccacatctgcaacaaccagcagcatcagagatcctaatgctttggct
ggccagaatggccctgaccatgctctcataggaggaatagtggctgtagttgtatttgtc
acgctgtgttctatctttctgcttggtcgatatctggcaaggcataaaggaacgtattta
acaaatgaagctaaaggagctgaagatgcaccagatgctgatacagccattatcaatgct
gaaggcagccaagtcaatgctgaagagaaaaaagagtatttcatttaa

KEGG   Homo sapiens (human): 56253
Entry
56253             CDS       T01001                                 
Symbol
CRTAM, CD355
Name
(RefSeq) cytotoxic and regulatory T cell molecule
  KO
K16361  cytotoxic and regulatory T-cell molecule
Organism
hsa  Homo sapiens (human)
Pathway
hsa04517  IgSF CAM signaling
Network
nt06546  IgSF CAM signaling
  Element
N01954  NECL2 interactions
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    56253 (CRTAM)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    56253 (CRTAM)
   04090 CD molecules [BR:hsa04090]
    56253 (CRTAM)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  Nectin family
   56253 (CRTAM)
CD molecules [BR:hsa04090]
 Proteins
  56253 (CRTAM)
SSDB
Motif
Pfam: Ig_3 C2-set_2 ig I-set V-set Ig_2 Adeno_E3_CR1 Izumo-Ig C2-set_3 DUF4834 Orf78 FraC PFF1_TM
Other DBs
NCBI-GeneID: 56253
NCBI-ProteinID: NP_062550
OMIM: 612597
HGNC: 24313
Ensembl: ENSG00000109943
UniProt: O95727
Structure
LinkDB
Position
11:122838500..122872643
AA seq 393 aa
MWWRVLSLLAWFPLQEASLTNHTETITVEEGQTLTLKCVTSLRKNSSLQWLTPSGFTIFL
NEYPALKNSKYQLLHHSANQLSITVPNVTLQDEGVYKCLHYSDSVSTKEVKVIVLATPFK
PILEASVIRKQNGEEHVVLMCSTMRSKPPPQITWLLGNSMEVSGGTLHEFETDGKKCNTT
STLIIHTYGKNSTVDCIIRHRGLQGRKLVAPFRFEDLVTDEETASDALERNSLSSQDPQQ
PTSTVSVTEDSSTSEIDKEEKEQTTQDPDLTTEANPQYLGLARKKSGILLLTLVSFLIFI
LFIIVQLFIMKLRKAHVIWKKENEVSEHTLESYRSRSNNEETSSEEKNGQSSHPMRCMNY
ITKLYSEAKTKRKENVQHSKLEEKHIQVPESIV
NT seq 1182 nt   +upstreamnt  +downstreamnt
atgtggtggagagttctcagcttgctggcatggttccccttgcaagaggcctctctgact
aaccacacagaaaccatcaccgtggaggaaggccagacgctcactctaaagtgtgtcact
tctctgaggaagaactcctccctccagtggctgaccccctcagggttcaccattttttta
aatgagtatcctgctttaaaaaattccaaataccagcttcttcatcactcggccaatcag
ctctccatcactgtgcctaacgtaaccctgcaagatgaaggcgtgtacaagtgcttacat
tacagcgactctgtaagcacaaaggaagtgaaagtgattgtgctggcaactcctttcaag
ccaatcctggaagcttcagttatcagaaagcaaaatggagaagaacatgttgtactcatg
tgctccaccatgagaagcaagccccctccgcagataacctggctacttgggaatagcatg
gaagtgtccggtggaacgctccatgaatttgaaactgatgggaagaaatgtaatactacc
agcactctcataatccacacttatggcaaaaattcaacggtggactgcattatccgacac
agaggcctgcaagggagaaaactagtagcacccttccggtttgaagatttggttactgat
gaagagacagcttcagatgctctggagagaaactctctatcctctcaagacccacagcag
cccaccagtactgtctcagtaacggaagattctagtacatcggagattgacaaggaagag
aaagaacaaaccactcaagatcctgacttgaccaccgaagcaaatcctcagtatttagga
ctggcaagaaagaaaagtggcatcctgctgctcacgctggtgtccttcctcattttcata
ctcttcatcatagtccagctcttcatcatgaagctgaggaaagcacatgtgatatggaag
aaagaaaacgaagtttcagaacacacactagaaagttacagatcaaggtcaaataatgaa
gaaacatcatctgaagagaaaaatggccaatcttcccaccctatgcgttgcatgaactac
atcacaaagttgtactcagaagcaaaaacaaagaggaaggaaaatgtacaacattcaaaa
ttagaagaaaagcacatccaagtaccagagagtattgtgtag

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