Homo sapiens (human): 2595
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Entry
2595 CDS
T01001
Symbol
GANC
Name
(RefSeq) glucosidase alpha, neutral C
KO
K12317
neutral alpha-glucosidase C [EC:
3.2.1.20
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00052
Galactose metabolism
hsa00500
Starch and sucrose metabolism
hsa01100
Metabolic pathways
Network
nt06017
Glycogen metabolism
Element
N00720
Glycogen degradation (amylase)
Drug target
Acarbose:
D00216
<JP/US>
Emiglitate:
D09779
Miglitol:
D00625
<JP/US>
Voglibose:
D01665
<JP>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00052 Galactose metabolism
2595 (GANC)
00500 Starch and sucrose metabolism
2595 (GANC)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.20 alpha-glucosidase
2595 (GANC)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glyco_hydro_31_2nd
Gal_mutarotas_2
Glyco_hydro_31_3rd
DUF5110
Motif
Other DBs
NCBI-GeneID:
2595
NCBI-ProteinID:
NP_937784
OMIM:
104180
HGNC:
4139
Ensembl:
ENSG00000214013
UniProt:
Q8TET4
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All DBs
Position
15:42273201..42353666
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AA seq
914 aa
AA seq
DB search
MEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQ
IINEASKVPLLAEIYGIEGNIFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGS
LILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQRAAKENEEET
SVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNT
GDGDAYRLYNLDVYGYQIYDKMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAV
EYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPL
FSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKR
MQELLRSKKRKLVVISDPHIKIDPDYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLD
FTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPEQTMQKNAIHHGNWEHREL
HNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIP
MLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGE
EHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSA
LLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAHWEGGCTVKIPVALDTIPVFQRGGSVIP
IKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSV
LINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEK
LSLNIATDWEVRII
NT seq
2745 nt
NT seq
+upstream
nt +downstream
nt
atggaagcagcagtgaaagaggaaataagtcttgaagatgaagctgtagataaaaacatt
ttcagagactgtaacaagatcgcattttacaggcgtcagaaacagtggctttccaagaag
tccacctatcaggcattattggattcagtcacaacagatgaagacagcaccaggttccaa
atcatcaatgaagcaagtaaggttcctctcctggctgaaatttatggtatagaaggaaac
attttcaggcttaaaattaatgaagagactcctctaaaacccagatttgaagttccggat
gtcctcacaagcaagccaagcactgtaaggctgatttcatgctctggggacacaggcagt
ctgatattggcagatggaaaaggagacctgaagtgccatatcacagcaaacccattcaag
gtagacttggtgtctgaagaagaggttgtgattagcataaattccctgggccaattatac
tttgagcatctacagattcttcacaaacaaagagctgctaaagaaaatgaggaggagaca
tcagtggacacctctcaggaaaatcaagaagatctgggcctgtgggaagagaaatttgga
aaatttgtggatatcaaagctaatggcccttcttctattggtttggatttctccttgcat
ggatttgagcatctttatgggatcccacaacatgcagaatcacaccaacttaaaaatact
ggtgatggagatgcttaccgtctttataacctggatgtctatggataccaaatatatgat
aaaatgggcatttatggttcagtaccttatctcctggcccacaaactgggcagaactata
ggtattttctggctgaatgcctcggaaacactggtggagatcaatacagagcctgcagta
gagtacacactgacccagatgggcccagttgctgctaaacaaaaggtcagatctcgcact
catgtgcactggatgtcagagagtggcatcattgatgtttttctgctgacaggacctaca
ccttctgatgtcttcaaacagtactcacaccttacaggcacacaagccatgccccctctt
ttctctttgggataccaccagtgccgctggaactatgaagatgagcaggatgtaaaagca
gtggatgcagggtttgatgagcatgacattccttatgatgccatgtggctggacatagag
cacactgagggcaagaggtacttcacctgggacaaaaacagattcccaaaccccaagagg
atgcaagagctgctcaggagcaaaaagcgtaagcttgtggtcatcagtgatccccacatc
aagattgatcctgactactcagtatatgtgaaggccaaagatcagggcttctttgtgaag
aatcaggaaggggaagactttgaaggggtgtgttggccaggtctctcctcttacctggat
ttcaccaatcccaaggtcagagagtggtattcaagtctttttgctttccctgtttatcag
ggatctacggacatcctcttcctttggaatgacatgaatgagccttctgtctttagaggg
ccagagcaaaccatgcagaagaatgccattcatcatggcaattgggagcacagagagctc
cacaacatctacggtttttatcatcaaatggctactgcagaaggactgataaaacgatct
aaagggaaggagagaccctttgttcttacacgttctttctttgctggatcacaaaagtat
ggtgccgtgtggacaggcgacaacacagcagaatggagcaacttgaaaatttctatccca
atgttactcactctcagcattactgggatctctttttgcggagctgacataggcgggttc
attgggaatccagagacagagctgctagtgcgttggtaccaggctggagcctaccagccc
ttcttccgtggccatgccaccatgaacaccaagcgacgagagccctggctctttggggag
gaacacacccgactcatccgagaagccatcagagagcgctatggcctcctgccatattgg
tattctctgttctaccatgcacacgtggcttcccaacctgtcatgaggcctctgtgggta
gagttccctgatgaactaaagacttttgatatggaagatgaatacatgctggggagtgca
ttattggttcatccagtcacagaaccaaaagccaccacagttgatgtgtttcttccagga
tcaaatgaggtctggtatgactataagacatttgctcattgggaaggagggtgtactgta
aagatcccagtagccttggacactattccagtgtttcagcgaggtggaagtgtgatacca
ataaagacaactgtaggaaaatccacaggctggatgactgaatcctcctatggactccgg
gttgctctaagcactaagggttcttcagtgggtgagttatatcttgatgatggccattca
ttccaatacctccaccagaagcaatttttgcacaggaagttttcattctgttccagtgtt
ctgatcaatagttttgctgaccagaggggtcattatcccagcaagtgtgtggtggagaag
atcttggtcttaggcttcaggaaggagccatcttctgtgactacccactcatctgatggt
aaagatcagcctgtggcttttacgtattgtgccaaaacatccatcctgagcctggagaag
ctctcactcaacattgccactgactgggaggtccgcatcatatga
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