KEGG   DRUG: MiglitolHelp
Entry
D00625                      Drug                                   

Name
Miglitol (JP17/USAN/INN);
Glyset (TN)
Product
  Generic
Formula
C8H17NO5
Exact mass
207.1107
Mol weight
207.2243
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antidiabetic agent
 DG01663  alpha-Glucosidase inhibitor
  DG01803  Antidiabetic, alpha-glucosidase inhibitor
 DG02044  Hypoglycemics
  DG01803  Antidiabetic, alpha-glucosidase inhibitor
Remark
Same as: C07708
Therapeutic category: 3969
ATC code: A10BF02
Product: D00625<JP/US>
Efficacy
Antidiabetic, alpha-Glucosidase inhibitor
  Disease
Type 2 diabetes mellitus [DS:H00409]
Comment
alpha-glucosidase inhibitors
Target
GAA [HSA:2548] [KO:K12316]
GANC [HSA:2595] [KO:K12317]
MGAM [HSA:8972] [KO:K12047]
  Pathway
hsa00052  Galactose metabolism
hsa00500  Starch and sucrose metabolism
hsa04973  Carbohydrate digestion and absorption
Interaction
Drug interaction
Structure map
map07051  Antidiabetics
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BF Alpha glucosidase inhibitors
     A10BF02 Miglitol
      D00625  Miglitol (JP17/USAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Blood Glucose Regulators
  Antidiabetic Agents
   Miglitol
    D00625  Miglitol (JP17/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   396  Antidiabetic agents
    3969  Others
     D00625  Miglitol (JP17/USAN/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Glycosidases
    GAA
     D00625  Miglitol (JP17/USAN/INN) <JP/US>
    GANC
     D00625  Miglitol (JP17/USAN/INN) <JP/US>
    MGAM
     D00625  Miglitol (JP17/USAN/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00625  Miglitol
Drug classes of therapeutic agents [br08360.html]
 Antidiabetic agents
  D00625
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D00625
BRITE hierarchy
Other DBs
CAS: 72432-03-2
PubChem: 7847691
ChEBI: 6935
ChEMBL: CHEMBL1561
DrugBank: DB00491
PDB-CCD: MIG[PDBj]
LigandBox: D00625
NIKKAJI: J22.799D
LinkDB All DBs
KCF data Show

ATOM        14
            1   N1y N    25.6615  -16.6519
            2   C1y C    24.4566  -17.3596
            3   C1x C    26.8780  -17.3304
            4   C1b C    25.7022  -15.2482
            5   C1y C    24.4042  -18.7692
            6   C1b C    23.2342  -16.6753
            7   C1y C    26.8957  -18.7282
            8   C1b C    26.8429  -14.5346
            9   C1y C    25.6967  -19.4477
            10  O1a O    23.2693  -19.4769
            11  O1a O    22.0352  -17.3889
            12  O1a O    28.1181  -19.4126
            13  O1a O    26.8254  -13.1309
            14  O1a O    25.7084  -20.8455
BOND        14
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Up
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     4   8 1
            8     5   9 1
            9     5  10 1 #Down
            10    6  11 1
            11    7  12 1 #Down
            12    8  13 1
            13    9  14 1 #Up
            14    7   9 1

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