Homo sapiens (human): 26060
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Entry
26060 CDS
T01001
Symbol
APPL1, APPL, DIP13alpha, MODY14
Name
(RefSeq) adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
KO
K08733
DCC-interacting protein 13 alpha
Organism
hsa
Homo sapiens (human)
Pathway
hsa04211
Longevity regulating pathway
hsa04920
Adipocytokine signaling pathway
hsa05200
Pathways in cancer
hsa05210
Colorectal cancer
Network
nt06231
Apoptosis (cancer)
nt06260
Colorectal cancer
nt06325
Hormone/cytokine signaling
Element
N00101
DCC-apoptotic pathway
N00102
Loss of DCC to DCC-apoptotic pathway
N01788
ADIPOQ-ADIPOR signaling pathway
Disease
H00410
Maturity onset diabetes of the young (MODY)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04920 Adipocytokine signaling pathway
26060 (APPL1)
09149 Aging
04211 Longevity regulating pathway
26060 (APPL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
26060 (APPL1)
09162 Cancer: specific types
05210 Colorectal cancer
26060 (APPL1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
26060 (APPL1)
Membrane trafficking [BR:
hsa04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
26060 (APPL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BAR_3
PID
PH
BAR
SOS1_NGEF_PH
PH_9
Gemin6
Motif
Other DBs
NCBI-GeneID:
26060
NCBI-ProteinID:
NP_036228
OMIM:
604299
HGNC:
24035
Ensembl:
ENSG00000157500
UniProt:
Q9UKG1
Structure
PDB
LinkDB
All DBs
Position
3:57227729..57273471
Genome browser
AA seq
709 aa
AA seq
DB search
MPGIDKLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHL
TSKLLKEYEKQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKE
RDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMH
YFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREM
DSDIETMQQTIEDLEVASDPLYVPDPDPTKFPVNRNLTRKAGYLNARNKTGLVSSTWDRQ
FYFTQGGNLMSQARGDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKKSSILQAESK
KDHEEWICTINNISKQIYLSENPEETAARVNQSALEAVTPSPSFQQRHESLRPAAGQSRP
PTARTSSSGSLGSESTNLAALSLDSLVAPDTPIQFDIISPVCEDQPGQAKAFGQGGRRTN
PFGESGGSTKSETEDSILHQLFIVRFLGSMEVKSDDHPDVVYETMRQILAARAIHNIFRM
TESHLLVTCDCLKLIDPQTQVTRLTFPLPCVVLYATHQENKRLFGFVLRTSSGRSESNLS
SVCYIFESNNEGEKICDSVGLAKQIALHAELDRRASEKQKEIERVKEKQQKELNKQKQIE
KDLEEQSRLIAASSRPNQASSEGQFVVLSSSQSEESDLGEGGKKRESEA
NT seq
2130 nt
NT seq
+upstream
nt +downstream
nt
atgccggggatcgacaagctgcccatcgaggagacgctggaggacagcccgcagacaagg
tctttactaggtgtatttgaagaagatgccacagctatttccaactatatgaaccagttg
tatcaagctatgcatcggatttatgatgcacagaatgaattaagtgcagcaacacacctg
acctcaaaacttttaaaagaatatgaaaaacagcgttttccattgggaggtgatgatgaa
gttatgagctctacattgcaacagttttcaaaagttatagatgagcttagctcttgtcat
gcagtgctttcaactcaacttgctgatgccatgatgttccccattacccagtttaaagaa
agagatctgaaagaaatactaacattaaaggaagtatttcagattgcaagtaatgatcat
gatgctgcgattaatagatatagccgtttatcaaaaaaaagagaaaatgacaaggtgaag
tatgaagtaacagaagatgtgtacacatccagaaagaaacaacaccagaccatgatgcat
tatttttgtgcattaaatactcttcagtacaagaagaaaatagcattgttagaacctcta
cttgggtacatgcaagctcagataagtttctttaagatgggttctgaaaatcttaatgaa
caactggaagaatttttagctaatattggaacaagcgttcagaatgttcgcagggaaatg
gacagtgatatagagaccatgcaacagacaatagaggatttggaagtagccagtgatccc
ttatatgtgcctgacccagaccccaccaaatttcctgttaatcgaaatttaacccgaaag
gctggataccttaatgctaggaataaaacaggcttggtgtcatctacctgggacagacag
ttttacttcacgcagggtggaaatttaatgagtcaggcccgtggggatgtagcaggaggc
ctggccatggacatagacaactgttcagtgatggctgtggactgtgaagacagacgatat
tgttttcagatcacctctttcgatggaaaaaaatcttcaattttgcaagcagagagtaaa
aaagatcatgaagagtggatctgtacaataaacaacatatctaaacaaatatacttaagt
gaaaatccagaggaaactgctgcacgagtaaatcaatcagctctggaagctgtcactcct
tccccatctttccagcagaggcacgagagcctgcggccagcagcaggacaatctcggcca
ccgacagctcgaaccagcagttcaggatccttaggatctgagtctacaaatttggctgcc
ctctctctagattctcttgttgccccagacaccccaatacagtttgacataatttctcct
gtgtgtgaagatcagcctggccaggcaaaagcctttggccagggaggcaggcgtacaaat
ccatttggagaatctggaggaagtacaaaatctgaaactgaagattctattcttcatcag
ttatttattgtccgattccttggttcaatggaggtgaaatcagatgaccatccagatgtt
gtttatgaaactatgcgccaaatcttagctgcccgggccatccataacatctttcgtatg
acagaatcgcatttattagtcacttgtgactgtttaaagttaattgatccacagacacaa
gttacaaggctcacgtttccattaccttgtgtagttttgtatgctacacaccaggaaaat
aagcgcctttttggatttgttcttcggacatcaagcgggagaagtgaaagtaatctgtca
tcagtctgctatatatttgagtcaaacaatgagggggaaaagatatgtgattctgttgga
ctggcaaaacagatagctttgcatgctgaactggatcgtagggcatcagaaaaacaaaaa
gaaatagagagagtaaaagagaagcaacagaaagaactcaataaacaaaaacagattgaa
aaggacttggaagaacaaagtcggttgatagctgcttccagtagaccaaaccaagccagt
agtgaggggcagtttgttgtccttagcagtagccagtcagaagagagtgatttgggagaa
ggaggaaagaagagagaatcagaagcataa
DBGET
integrated database retrieval system
