KEGG   Homo sapiens (human): 2687
Entry
2687              CDS       T01001                                 
Symbol
GGT5, GGL, GGT_5, GGT-REL, GGTLA1
Name
(RefSeq) gamma-glutamyltransferase 5
  KO
K18592  gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00430  Taurine and hypotaurine metabolism
hsa00480  Glutathione metabolism
hsa00590  Arachidonic acid metabolism
hsa01100  Metabolic pathways
Drug target
Acivicin: D02755
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    2687 (GGT5)
  09106 Metabolism of other amino acids
   00430 Taurine and hypotaurine metabolism
    2687 (GGT5)
   00480 Glutathione metabolism
    2687 (GGT5)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    2687 (GGT5)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    2687 (GGT5)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.2  gamma-glutamyltransferase
     2687 (GGT5)
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.13  glutathione gamma-glutamate hydrolase
     2687 (GGT5)
    3.4.19.14  leukotriene-C4 hydrolase
     2687 (GGT5)
Peptidases and inhibitors [BR:hsa01002]
 Threonine peptidases
  Family T3: gamma-glutamyltransferase family
   2687 (GGT5)
CD molecules [BR:hsa04090]
 Proteins
  2687 (GGT5)
SSDB
Motif
Pfam: G_glu_transpept
Other DBs
NCBI-GeneID: 2687
NCBI-ProteinID: NP_004112
OMIM: 137168
HGNC: 4260
Ensembl: ENSG00000099998
UniProt: P36269
LinkDB
Position
22:complement(24219654..24245142)
AA seq 586 aa
MARGYGATVSLVLLGLGLALAVIVLAVVLSRHQAPCGPQAFAHAAVAADSKVCSDIGRAI
LQQQGSPVDATIAALVCTSVVNPQSMGLGGGVIFTIYNVTTGKVEVINARETVPASHAPS
LLDQCAQALPLGTGAQWIGVPGELRGYAEAHRRHGRLPWAQLFQPTIALLRGGHVVAPVL
SRFLHNSILRPSLQASTLRQLFFNGTEPLRPQDPLPWPALATTLETVATEGVEVFYTGRL
GQMLVEDIAKEGSQLTLQDLAKFQPEVVDALEVPLGDYTLYSPPPPAGGAILSFILNVLR
GFNFSTESMARPEGRVNVYHHLVETLKFAKGQRWRLGDPRSHPKLQNASRDLLGETLAQL
IRQQIDGRGDHQLSHYSLAEAWGHGTGTSHVSVLGEDGSAVAATSTINTPFGAMVYSPRT
GIILNNELLDLCERCPRGSGTTPSPVSGDRVGGAPGRCWPPVPGERSPSSMVPSILINKA
QGSKLVIGGAGGELIISAVAQAIMSKLWLGFDLRAAIAAPILHVNSKGCVEYEPNFSQEV
QRGLQDRGQNQTQRPFFLNVVQAVSQEGACVYAVSDLRKSGEAAGY
NT seq 1761 nt   +upstreamnt  +downstreamnt
atggcccggggctacggggccacggtcagcctagtcctgctgggtctggggctggcgctg
gctgtcattgtgctggctgtggtcctctctcgacaccaggccccatgtggcccccaggcc
tttgcccacgctgctgttgccgccgactccaaggtctgctcggatattggacgagccatc
ctccagcagcagggctcacccgtggatgccaccatcgcggctctggtctgcaccagcgtc
gtcaaccctcagagcatgggcctgggcggaggggtcatcttcaccatctacaatgtgaca
acagggaaggtggaggtcatcaatgcccgggagacggtgccggccagccacgccccgagc
ctgctggaccagtgtgcacaggctctgccactgggcacaggggcccagtggatcggggtg
cccggggagctccgtggctatgccgaggcccaccgccgccatggccgcctgccctgggcg
cagctgttccagcccaccatcgcgctgctccgaggggggcatgtggtggcccctgtcctc
agccgtttcctgcacaacagcatcctgcggccttccttgcaggcgtcaaccctgcgccag
ctcttcttcaacgggacagaacccctgaggcctcaggacccactcccatggcctgcactg
gccaccaccctggagaccgtggccacagagggcgtggaggtcttctacacggggaggctg
ggccagatgctggtggaggacattgccaaggaagggagccagctgacgctgcaggacctg
gccaagttccagcccgaggtggtggatgccctggaggtgcccctgggggactataccctg
tactcaccaccgccgcctgcagggggtgccattctcagctttatcctcaacgtgctaaga
gggttcaacttctcaacagagtctatggccaggcctgaagggagggtgaacgtgtaccac
caccttgtagagacgctcaagtttgccaaggggcagaggtggaggctgggggaccctcga
agccacccgaagctccagaatgcctcccgggacctgctgggggagaccctggcccagctc
atccgccaacagatcgatggccggggggaccaccagctcagccactacagcttggccgag
gcctggggccacgggacaggcacgtcccatgtgtctgtgctgggggaggatggcagcgcc
gtggctgccaccagcaccatcaacacaccctttggagcgatggtgtattcaccacggaca
ggcatcatcctcaacaacgagctcctggacttatgcgagcgatgcccccggggttccggc
accaccccctcacctgtgagtggagacagggtgggtggagctcccggaaggtgctggccc
ccagttccaggcgagcgttccccatcctccatggtgccctccatcttgatcaacaaagcc
caggggtcgaagctagtgattggcggggctggcggggagctcatcatctctgctgtggcc
caggccatcatgagcaagctgtggcttggctttgacctgagagcggccattgcagccccc
atcctgcatgtcaacagcaagggctgtgtggagtacgagcccaacttcagccaggaggtg
cagaggggactccaagaccgtggccagaaccagacccagaggcccttcttcctgaacgtg
gtccaggctgtgtcccaggagggggcctgtgtgtacgccgtctcggacctgaggaagagt
ggggaggccgcaggctactaa

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