KEGG   Homo sapiens (human): 27128
Entry
27128             CDS       T01001                                 
Symbol
CYTH4, CYT4, DJ63G5.1, PSCD4, cytohesin-4
Name
(RefSeq) cytohesin-4 isoform 1
  KO
K18441  cytohesin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04072  Phospholipase D signaling pathway
hsa04144  Endocytosis
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    27128 (CYTH4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    27128 (CYTH4)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    27128 (CYTH4)
   05132 Salmonella infection
    27128 (CYTH4)
   05131 Shigellosis
    27128 (CYTH4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    27128 (CYTH4)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Arf GTPases and associated proteins
   Arf associated proteins
    27128 (CYTH4)
 Endosome - Golgi transport
   Arf GTPase associated proteins
    27128 (CYTH4)
SSDB
Motif
Pfam: Sec7 PH PH_11 STX6_10_61_N PH_8 PH_20 PH_3 PH_RASGAP
Other DBs
NCBI-GeneID: 27128
NCBI-ProteinID: NP_037517
OMIM: 606514
HGNC: 9505
Ensembl: ENSP00000248901.6
UniProt: Q9UIA0
LinkDB
Position
22:37282508..37315341
AA seq 394 aa
MDLCHPEPAELSSGETEELQRIKWHRKQLLEDIQKLKDEIADVFAQIDCFESAEESRMAQ
KEKELCIGRKKFNMDPAKGIQYFIEHKLLTPDVQDIARFLYKGEGLNKTAIGTYLGERDP
INLQVLQAFVDCHEFANLNLVQALRQFLWSFRLPGEAQKIDRMMEAFATRYCLCNPGVFQ
STDTCYVLSFSIIMLNTSLHNPNVRDRPPFERFVSMNRGINNGSDLPEDQLRNLFDSIKS
EPFSIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEFTTDKEPR
GIIPLENLSVQKVDDPKKPFCLELYNPSCRGQKIKACKTDGDGRVVEGKHESYRISATSA
EERDQWIESIRASITRVPFYDLVSTRKKKIASKQ
NT seq 1185 nt   +upstreamnt  +downstreamnt
atggacctgtgccacccagagcccgcggagctgagcagcggggagacggaagagttacag
aggatcaagtggcaccgaaagcagctcctggaggacatccagaagctgaaggatgagatt
gcagatgtgtttgcccaaatcgactgcttcgagagtgcggaggagagccggatggcccag
aaggagaaggagctgtgtattgggcgcaagaagttcaacatggaccccgccaagggtatc
cagtatttcattgagcacaagctgctgacccctgacgtccaggacattgcacggttcctg
tataaaggcgagggcctcaacaagacagccattggtacctacctgggggagagggatccc
atcaacctgcaggtcctccaggccttcgtggactgccacgagttcgccaacctcaacctc
gtccaggccctcaggcagttcctgtggagcttccggctgccgggcgaggcccagaagata
gaccggatgatggaggcctttgccactcgatactgcctctgcaacccaggcgtcttccag
tccacagacacctgctacgtgttgtccttctccatcatcatgctcaacaccagcctccac
aatcccaacgtccgggacaggccgccttttgagcgctttgtgtccatgaaccgcggcatc
aacaatggtagcgacctgcccgaggaccagctgcggaacctcttcgacagcatcaagagt
gagccattctccatccctgaggacgacggcaatgacctcactcacaccttcttcaatcca
gaccgggagggttggctgctcaagctagggggccgcgtgaagacgtggaaacggcgctgg
ttcatcctgaccgacaactgcctctactacttcgagttcaccactgacaaggagccacgg
ggaattatacctcttgagaacctctcggtgcagaaggtggatgaccccaagaagccattc
tgcctggagctctacaaccctagctgccgaggccagaaaatcaaggcctgcaagaccgat
ggcgacggcagggtggtggagggcaagcacgaatcgtaccgcatctcagccaccagtgcc
gaggaacgtgaccagtggatcgagtccatccgagccagcatcacccgtgtccccttctac
gacctggtctctactcggaagaagaagattgccagcaagcagtga

KEGG   Homo sapiens (human): 9265
Entry
9265              CDS       T01001                                 
Symbol
CYTH3, ARNO3, GRP1, PSCD3, cytohesin-3
Name
(RefSeq) cytohesin-3 isoform b
  KO
K18441  cytohesin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04072  Phospholipase D signaling pathway
hsa04144  Endocytosis
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    9265 (CYTH3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    9265 (CYTH3)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    9265 (CYTH3)
   05132 Salmonella infection
    9265 (CYTH3)
   05131 Shigellosis
    9265 (CYTH3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    9265 (CYTH3)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Arf GTPases and associated proteins
   Arf associated proteins
    9265 (CYTH3)
 Endosome - Golgi transport
   Arf GTPase associated proteins
    9265 (CYTH3)
SSDB
Motif
Pfam: Sec7 PH PH_8 PH_11 PH_20 SOS1_NGEF_PH PH_3 PH_MRCK
Other DBs
NCBI-GeneID: 9265
NCBI-ProteinID: NP_001354509
OMIM: 605081
HGNC: 9504
UniProt: B7Z2V9
LinkDB
Position
7:complement(6161779..6272624)
AA seq 314 aa
MALPQLQTAMLAAFLWDPRDVVLTAQPGAEQCAESSQHIRILQPQFRLIRLRFWKLYIQR
RVQAWQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLH
NHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNP
DREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPN
CFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFY
DMLATRKRRIANKK
NT seq 945 nt   +upstreamnt  +downstreamnt
atggccttacctcaactgcagactgcaatgttggcagcgtttttgtgggaccctcgtgat
gttgtgctcacagcgcagcctggggctgaacagtgcgctgagagttcgcaacatataaga
atcctgcagccgcagttcaggcttatcagattgcgtttctggaagctgtacatccagaga
agggtgcaggcctggcagttcttatggagcttcaggctgcccggggaggcgcagaagatt
gatcgcatgatggaggctttcgcttctcgctactgcctgtgcaaccccggggtcttccag
tccacagacacgtgctacgtgctgtcattcgccatcatcatgctcaacaccagcctccac
aaccacaacgtgcgtgacaagcccacggcagaacggttcatcgccatgaaccgcggcatc
aacgagggcggggacctccctgaggagctgctgaggaatttgtatgagagcattaagaac
gagccatttaagatcccggaggacgacgggaacgacctgacccacaccttcttcaacccc
gaccgcgagggctggctcctgaagctgggagggcgtgtgaagacctggaagcgccggtgg
ttcatcctgaccgataactgcctctattactttgaatacacaacagataaggagcccagg
ggaatcatcccgttggaaaacctcagcatcagggaggtggaggacccccggaaacccaac
tgttttgagctctacaatcccagccacaaagggcaggtcatcaaggcctgtaagactgag
gccgacggccgcgtggtagaggggaaccatgtggtgtaccggatctcagccccgagcccg
gaggagaaggaggagtggatgaaatccatcaaagccagtatcagcagagatcccttctat
gacatgttggcaacgaggaaacgaaggattgccaataaaaaatag

KEGG   Homo sapiens (human): 9266
Entry
9266              CDS       T01001                                 
Symbol
CYTH2, ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like, cytohesin-2
Name
(RefSeq) cytohesin-2 isoform 1
  KO
K18441  cytohesin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04072  Phospholipase D signaling pathway
hsa04144  Endocytosis
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    9266 (CYTH2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    9266 (CYTH2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    9266 (CYTH2)
   05132 Salmonella infection
    9266 (CYTH2)
   05131 Shigellosis
    9266 (CYTH2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    9266 (CYTH2)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Arf GTPases and associated proteins
   Arf associated proteins
    9266 (CYTH2)
 Endosome - Golgi transport
   Arf GTPase associated proteins
    9266 (CYTH2)
SSDB
Motif
Pfam: Sec7 PH PH_8 PH_11 PH_20 PH_3 SOS1_NGEF_PH FlgN NUDE_C
Other DBs
NCBI-GeneID: 9266
NCBI-ProteinID: NP_059431
OMIM: 602488
HGNC: 9502
UniProt: Q99418
Structure
LinkDB
Position
19:48469369..48482314
AA seq 400 aa
MEDGVYEPPDLTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEANEGSKTLQ
RNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREE
LNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQ
STDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIRN
EPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEP
RGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPT
QEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP
NT seq 1203 nt   +upstreamnt  +downstreamnt
atggaggacggcgtctatgaacccccagacctgactccggaggagcggatggagctggag
aacatccggcggcggaagcaggagctgctggtggagattcagcgcctgcgggaggagctc
agtgaagccatgagcgaggtggaggggctggaggccaatgagggcagtaagaccttgcaa
cggaaccggaagatggcaatgggcaggaagaagttcaacatggaccccaagaaggggatc
cagttcttggtggagaatgaactgctgcagaacacacccgaggagatcgcccgcttcctg
tacaagggcgaggggctgaacaagacagccatcggggactacctgggggagagggaagaa
ctgaacctggcagtgctccatgcttttgtggatctgcatgagttcaccgacctcaatctg
gtgcaggccctcaggcagtttctatggagctttcgcctacccggagaggcccagaaaatt
gaccggatgatggaggccttcgcccagcgatactgcctgtgcaaccctggggttttccag
tccacagacacgtgctatgtgctgtccttcgccgtcatcatgctcaacaccagtctccac
aatcccaatgtccgggacaagccgggcctggagcgctttgtggccatgaaccggggcatc
aacgagggcggggacctgcctgaggagctgctcaggaacctgtacgacagcatccgaaat
gagcccttcaagattcctgaggatgacgggaatgacctgacccacaccttcttcaacccg
gaccgggagggctggctcctgaagctgggagggggccgggtgaagacgtggaagcggcgc
tggtttatcctcacagacaactgcctctactactttgagtacaccacggacaaggagccc
cgaggaatcatccccctggagaatctgagcatccgagaggtggacgacccccggaaaccg
aactgctttgaactttacatccccaacaacaaggggcagctcatcaaagcctgcaaaact
gaggcggacggccgagtggtggagggaaaccacatggtgtaccggatctcggcccccacg
caggaggagaaggacgagtggatcaagtccatccaggcggctgtgagtgtggaccccttc
tatgagatgctggcagcgagaaagaagcggatttcagtcaagaagaagcaggagcagccc
tga

KEGG   Homo sapiens (human): 9267
Entry
9267              CDS       T01001                                 
Symbol
CYTH1, B2-1, CYTOHESIN-1, D17S811E, PSCD1, SEC7
Name
(RefSeq) cytohesin-1 isoform 1
  KO
K18441  cytohesin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04072  Phospholipase D signaling pathway
hsa04144  Endocytosis
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    9267 (CYTH1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    9267 (CYTH1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    9267 (CYTH1)
   05132 Salmonella infection
    9267 (CYTH1)
   05131 Shigellosis
    9267 (CYTH1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    9267 (CYTH1)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Arf GTPases and associated proteins
   Arf associated proteins
    9267 (CYTH1)
 Endosome - Golgi transport
   Arf GTPase associated proteins
    9267 (CYTH1)
SSDB
Motif
Pfam: Sec7 PH PH_8 PH_11 SOS1_NGEF_PH APG6_N PH_20 PH_3 FapA SLX9 GPS2_interact Kebab_C Pilosulin Sec10_N PH_MRCK
Other DBs
NCBI-GeneID: 9267
NCBI-ProteinID: NP_004753
OMIM: 182115
HGNC: 9501
Ensembl: ENSP00000389095.3
UniProt: Q15438
Structure
LinkDB
Position
17:complement(78674048..78782273)
AA seq 398 aa
MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNM
QRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERD
EFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVF
QSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIK
NEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKE
PRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAP
TPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
NT seq 1197 nt   +upstreamnt  +downstreamnt
atggaggaggacgacagctacgttcccagtgacctgacagcagaggagcgtcaagaactg
gagaacatccgacggagaaaacaggagctgctggctgacattcagaggctgaaggatgag
atagcagaagtagctaatgaaattgaaaacctgggatccacagaggaaaggaaaaacatg
cagaggaacaaacaggtagccatgggcaggaaaaaatttaatatggaccctaaaaagggg
atccagttcttaatagagaacgacctcctgaagaacacttgtgaagacattgcccagttc
ttatataaaggcgaagggctcaacaagacagccatcggcgactacctaggggagagagat
gagtttaatatccaggttcttcatgcatttgtggagctgcatgagttcactgatcttaat
ctcgtccaggcactacggcagttcctgtggagcttccggctacccggagaggcccagaag
atcgaccggatgatggaggcgtttgcccagcgatattgtcagtgcaataatggcgtgttc
cagtccacggatacttgttacgtcctctcctttgccatcatcatgttgaacaccagtctg
cacaaccccaatgtcaaagataagcccactgtggagaggttcattgccatgaaccgaggc
atcaatgatgggggagacctgccggaggagctcctccggaatctctatgagagcataaaa
aatgaaccctttaaaatcccagaagacgacgggaatgacctcactcacactttcttcaat
ccagaccgagaaggctggctattgaaactcggaggtggcagggtaaagacttggaagaga
cgctggttcattctgactgacaactgcctttactactttgagtataccacggataaggag
ccccgtggaatcatccctttagagaatctgagtatccgggaagtggaggactccaaaaaa
ccaaactgctttgagctttatatccccgacaataaagaccaagttatcaaggcctgcaag
accgaggctgacgggcgggtggtggaggggaaccacactgtttaccggatctcagctccg
acgcccgaggagaaggaggagtggattaagtgcattaaagcagccatcagcagggaccct
ttctacgaaatgctcgcagcacggaaaaagaaggtctcctccacgaagcgacactga

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