Homo sapiens (human): 2731
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Entry
2731 CDS
T01001
Symbol
GLDC, GCE, GCE1, GCSP, HYGN1
Name
(RefSeq) glycine decarboxylase
KO
K00281
glycine cleavage system P protein (glycine dehydrogenase) [EC:
1.4.4.2
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00260
Glycine, serine and threonine metabolism
hsa00630
Glyoxylate and dicarboxylate metabolism
hsa00670
One carbon pool by folate
hsa00785
Lipoic acid metabolism
hsa01100
Metabolic pathways
hsa01200
Carbon metabolism
Module
hsa_M00621
Glycine cleavage system
Network
nt06032
Lipoic acid metabolism
nt06033
Glycine, serine and arginine metabolism
Element
N01611
Glycine cleavage system
N01613
Glycine cleavage system, Gly to MTHF
Disease
H00191
Nonketotic hyperglycinemia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
2731 (GLDC)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
2731 (GLDC)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
2731 (GLDC)
00670 One carbon pool by folate
2731 (GLDC)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.4 Acting on the CH-NH2 group of donors
1.4.4 With a disulfide as acceptor
1.4.4.2 glycine dehydrogenase (aminomethyl-transferring)
2731 (GLDC)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GDC-P
GcvP2_C
Beta_elim_lyase
Aminotran_5
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
2731
NCBI-ProteinID:
NP_000161
OMIM:
238300
HGNC:
4313
Ensembl:
ENSG00000178445
UniProt:
P23378
Structure
PDB
PDBj
LinkDB
All DBs
Position
9:complement(6532467..6645729)
Genome browser
AA seq
1020 aa
AA seq
DB search
MQSCARAWGLRLGRGVGGGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRH
DDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDPVCENEILATL
HAISSKNQIWRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQ
TMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRRKFLVDPRCHPQTIAVVQTRAKYT
GVLTELKLPCEMDFSGKDVSGVLFQYPDTEGKVEDFTELVERAHQSGSLACCATDLLALC
ILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEV
YRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLEHIARRVHNATLILSE
GLKRAGHQLQHDLFFDTLKIQCGCSVKEVLGRAAQRQINFRLFEDGTLGISLDETVNEKD
LDDLLWIFGCESSAELVAESMGEECRGIPGSVFKRTSPFLTHQVFNSYHSETNIVRYMKK
LENKDISLVHSMIPLGSCTMKLNSSSELAPITWKEFANIHPFVPLDQAQGYQQLFRELEK
DLCELTGYDQVCFQPNSGAQGEYAGLATIRAYLNQKGEGHRTVCLIPKSAHGTNPASAHM
AGMKIQPVEVDKYGNIDAVHLKAMVDKHKENLAAIMITYPSTNGVFEENISDVCDLIHQH
GGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPFL
PNHPVISLKRNEDACPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKQATETAILNANYM
AKRLETHYRILFRGARGYVGHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVA
GTLMVEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHW
DRPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS
NT seq
3063 nt
NT seq
+upstream
nt +downstream
nt
atgcagtcctgtgccagggcgtgggggctgcgcctgggccgcggggtcgggggcggccgc
cgcctggctgggggatcggggccgtgctgggcgccgcggagccgggacagcagcagtggc
ggcggggacagcgccgcggctggggcctcgcgcctcctggagcgccttctgcccagacac
gacgacttcgctcggaggcacatcggccctggggacaaagaccagagagagatgctgcag
accttggggctggcgagcattgatgaattgatcgagaagacggtccctgccaacatccgt
ttgaaaagacccttgaaaatggaagaccctgtttgtgaaaatgaaatccttgcaactctg
catgccatttcaagcaaaaaccagatctggagatcgtatattggcatgggctattataac
tgctcagtgccacagacgattttgcggaacttactggagaactcaggatggatcacccag
tatactccataccagcctgaggtgtctcaggggaggctggagagtttactcaactaccag
accatggtgtgtgacatcacaggcctggacatggccaatgcatccctgctggatgagggg
actgcagccgcagaggcactgcagctgtgctacagacacaacaagaggaggaaatttctc
gttgatccccgttgccacccacagacaatagctgttgtccagactcgagccaaatatact
ggagtcctcactgagctgaagttaccctgtgaaatggacttcagtggaaaagatgtcagt
ggagtgttgttccagtacccagacacggaggggaaggtggaagactttacggaactcgtg
gagagagctcatcagagtgggagcctggcctgctgtgctactgaccttttagctttgtgc
atcttgaggccacctggagaatttggggtagacatcgccctgggcagctcccagagattt
ggagtgccactgggctatgggggaccccatgcagcattttttgctgtccgagaaagcttg
gtgagaatgatgcctggaagaatggtgggggtaacaagagatgccactgggaaagaagtg
tatcgtcttgctcttcaaaccagggagcaacacattcggagagacaaggctaccagcaac
atctgtacagctcaggccctcttggcgaatatggctgccatgtttgcaatctaccatggt
tcccatgggctggagcatattgctaggagggtacataatgccactttgattttgtcagaa
ggtctcaagcgagcagggcatcaactccagcatgacctgttctttgataccttgaagatt
cagtgtggctgctcagtgaaggaggtcttgggcagggccgctcagcggcagatcaatttt
cggctttttgaggatggcacacttggtatttctcttgatgaaacagtcaatgaaaaagat
ctggacgatttgttgtggatctttggttgtgagtcatctgcagaactggttgctgaaagc
atgggagaggagtgcagaggtattccagggtctgtgttcaagaggaccagcccgttcctc
acccatcaagtgttcaacagctaccactctgaaacaaacattgtccggtacatgaagaaa
ctggaaaataaagacatttcccttgttcacagcatgattccactgggatcctgcaccatg
aaactgaacagttcgtctgaactcgcacctatcacatggaaagaatttgcaaacatccac
ccctttgtgcctctggatcaagctcaaggatatcagcagcttttccgagagcttgagaag
gatttgtgtgaactcacaggttatgaccaggtctgtttccagccaaacagcggagcccag
ggagaatatgctggactggccactatccgagcctacttaaaccagaaaggagaggggcac
agaacggtttgcctcattccgaaatcagcacatgggaccaacccagcaagtgcccacatg
gcaggcatgaagattcagcctgtggaggtggataaatatgggaatatcgatgcagttcac
ctcaaggccatggtggataagcacaaggagaacctagcagctatcatgattacataccca
tccaccaatggggtgtttgaagagaacatcagtgacgtgtgtgacctcatccatcaacat
ggaggacaggtctacctagacggggcaaatatgaatgctcaggtgggaatctgtcgccct
ggagacttcgggtctgatgtctcgcacctaaatcttcacaagaccttctgcattccccac
ggaggaggtggtcctggcatggggcccatcggagtgaagaaacatctcgccccgtttttg
cccaatcatcccgtcatttcactaaagcggaatgaggatgcctgtcctgtgggaaccgtc
agtgcggccccatggggctccagttccatcttgcccatttcctgggcttatatcaagatg
atgggaggcaagggtcttaaacaagccacggaaactgcgatattaaatgccaactacatg
gccaagcgattagaaacacactacagaattcttttcaggggtgcaagaggttatgtgggt
catgaatttattttggacacgagacccttcaaaaagtctgcaaatattgaggctgtggat
gtggccaagagactccaggattatggatttcacgcccctaccatgtcctggcctgtggca
gggaccctcatggtggagcccactgagtcggaggacaaggcagagctggacagattctgt
gatgccatgatcagcattcggcaggaaattgctgacattgaggagggccgcatcgacccc
agggtcaatccgctgaagatgtctccacactccctgacctgcgttacatcttcccactgg
gaccggccttattccagagaggtggcagcattcccactccccttcgtgaaaccagagaac
aaattctggccaacgattgcccggattgatgacatatatggagatcagcacctggtttgt
acctgcccacccatggaagtttatgagtctccattttctgaacaaaagagggcgtcttct
tag
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integrated database retrieval system
