Homo sapiens (human): 27329
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Entry
27329 CDS
T01001
Symbol
ANGPTL3, ANG-5, ANGPT5, ANL3, FHBL2
Name
(RefSeq) angiopoietin like 3
KO
K22288
angiopoietin-like 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04979
Cholesterol metabolism
Disease
H01270
Familial hypobetalipoproteinemia
Drug target
Evinacumab:
D11753
<JP/US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
27329 (ANGPTL3)
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Gene cluster
GFIT
Motif
Pfam:
Fibrinogen_C
FAM186A-B_C
Crescentin
CCDC113_CCDC96_CC
DUF3209
ISG65-75
DUF1664
Motif
Other DBs
NCBI-GeneID:
27329
NCBI-ProteinID:
NP_055310
OMIM:
604774
HGNC:
491
Ensembl:
ENSG00000132855
UniProt:
Q9Y5C1
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:62597520..62606313
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AA seq
460 aa
AA seq
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MFTIKLLLFIVPLVISSRIDQDNSSFDSLSPEPKSRFAMLDDVKILANGLLQLGHGLKDF
VHKTKGQINDIFQKLNIFDQSFYDLSLQTSEIKEEEKELRRTTYKLQVKNEEVKNMSLEL
NSKLESLLEEKILLQQKVKYLEEQLTNLIQNQPETPEHPEVTSLKTFVEKQDNSIKDLLQ
TVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKPRAPRTTPFLQLNEIRNVKHD
GIPAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDVISGSPWTLIQHRIDGSQNFNETWE
NYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEYSFYLGNHETNYTL
HLVAITGNVPNAIPENKDLVFSTWDHKAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKP
RAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHPTDSESFE
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
atgttcacaattaagctccttctttttattgttcctctagttatttcctccagaattgat
caagacaattcatcatttgattctctatctccagagccaaaatcaagatttgctatgtta
gacgatgtaaaaattttagccaatggcctccttcagttgggacatggtcttaaagacttt
gtccataagacgaagggccaaattaatgacatatttcaaaaactcaacatatttgatcag
tctttttatgatctatcgctgcaaaccagtgaaatcaaagaagaagaaaaggaactgaga
agaactacatataaactacaagtcaaaaatgaagaggtaaagaatatgtcacttgaactc
aactcaaaacttgaaagcctcctagaagaaaaaattctacttcaacaaaaagtgaaatat
ttagaagagcaactaactaacttaattcaaaatcaacctgaaactccagaacacccagaa
gtaacttcacttaaaacttttgtagaaaaacaagataatagcatcaaagaccttctccag
accgtggaagaccaatataaacaattaaaccaacagcatagtcaaataaaagaaatagaa
aatcagctcagaaggactagtattcaagaacccacagaaatttctctatcttccaagcca
agagcaccaagaactactccctttcttcagttgaatgaaataagaaatgtaaaacatgat
ggcattcctgctgaatgtaccaccatttataacagaggtgaacatacaagtggcatgtat
gccatcagacccagcaactctcaagtttttcatgtctactgtgatgttatatcaggtagt
ccatggacattaattcaacatcgaatagatggatcacaaaacttcaatgaaacgtgggag
aactacaaatatggttttgggaggcttgatggagaattttggttgggcctagagaagata
tactccatagtgaagcaatctaattatgttttacgaattgagttggaagactggaaagac
aacaaacattatattgaatattctttttacttgggaaatcacgaaaccaactatacgcta
catctagttgcgattactggcaatgtccccaatgcaatcccggaaaacaaagatttggtg
ttttctacttgggatcacaaagcaaaaggacacttcaactgtccagagggttattcagga
ggctggtggtggcatgatgagtgtggagaaaacaacctaaatggtaaatataacaaacca
agagcaaaatctaagccagagaggagaagaggattatcttggaagtctcaaaatggaagg
ttatactctataaaatcaaccaaaatgttgatccatccaacagattcagaaagctttgaa
tga
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