Homo sapiens (human): 2733
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Entry
2733 CDS
T01001
Symbol
GLE1, CAAHC, CAAHD, GLE1L, LCCS, LCCS1, hGLE1
Name
(RefSeq) GLE1 RNA export mediator
KO
K18723
nucleoporin GLE1
Organism
hsa
Homo sapiens (human)
Pathway
hsa03013
Nucleocytoplasmic transport
hsa03015
mRNA surveillance pathway
hsa05014
Amyotrophic lateral sclerosis
Network
nt06464
Amyotrophic lateral sclerosis
Element
N01152
Nuclear export of mRNA
N01153
Mutation-caused aberrant GLE1 to nuclear export of mRNA
Disease
H00865
Lethal congenital contractural syndrome
H01030
Congenital arthrogryposis with anterior horn cell disease
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
03013 Nucleocytoplasmic transport
2733 (GLE1)
03015 mRNA surveillance pathway
2733 (GLE1)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
2733 (GLE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
2733 (GLE1)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
Transport factors
Nuclear pore complex
2733 (GLE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GLE1
Motif
Other DBs
NCBI-GeneID:
2733
NCBI-ProteinID:
NP_001003722
OMIM:
603371
HGNC:
4315
Ensembl:
ENSG00000119392
Pharos:
Q53GS7
(Tbio)
UniProt:
Q53GS7
Structure
PDB
PDBj
LinkDB
All DBs
Position
9:128504692..128542288
Genome browser
AA seq
698 aa
AA seq
DB search
MPSEGRCWETLKALRSSDKGRLCYYRDWLLRREDVLEECMSLPKLSSYSGWVVEHVLPHM
QENQPLSETSPSSTSASALDQPSFVPKSPDASSAFSPASPATPNGTKGKDESQHTESMVL
QSSRGIKVEGCVRMYELVHRMKGTEGLRLWQEEQERKVQALSEMASEQLKRFDEWKELKQ
HKEFQDLREVMEKSSREALGHQEKLKAEHRHRAKILNLKLREAEQQRVKQAEQERLRKEE
GQIRLRALYALQEEMLQLSQQLDASEQHKALLKVDLAAFQTRGNQLCSLISGIIRASSES
SYPTAESQAEAERALREMRDLLMNLGQEITRACEDKRRQDEEEAQVKLQEAQMQQGPEAH
KEPPAPSQGPGGKQNEDLQVKVQDITMQWYQQLQDASMQCVLTFEGLTNSKDSQAKKIKM
DLQKAATIPVSQISTIAGSKLKEIFDKIHSLLSGKPVQSGGRSVSVTLNPQGLDFVQYKL
AEKFVKQGEEEVASHHEAAFPIAVVASGIWELHPRVGDLILAHLHKKCPYSVPFYPTFKE
GMALEDYQRMLGYQVKDSKVEQQDNFLKRMSGMIRLYAAIIQLRWPYGNRQEIHPHGLNH
GWRWLAQILNMEPLSDVTATLLFDFLEVCGNALMKQYQVQFWKMLILIKEDYFPRIEAIT
SSGQMGSFIRLKQFLEKCLQHKDIPVPKGFLTSSFWRS
NT seq
2097 nt
NT seq
+upstream
nt +downstream
nt
atgccgtctgagggtcgctgctgggagaccttgaaggccctacgcagttccgacaaaggt
cgcctttgctactaccgcgactggctgctgcggcgcgaggatgttttagaagaatgtatg
tctcttcccaagctatcttcttattctggatgggtggtagagcacgtcctaccccatatg
caggagaaccaacctctgtctgagacttcgccatcctctacgtcagcttcagccctagat
caaccctcatttgttcccaaatctcctgacgcaagctctgccttttccccagcctcccct
gcaacaccaaatggaaccaagggcaaagatgagtcccagcacacagaatctatggtactt
cagtcctcacgggggatcaaagtggaaggctgcgtccgaatgtacgaactggtacacaga
atgaaaggaacagagggcctgaggctatggcaggaggagcaggagaggaaggtgcaagcc
ctctcggagatggcatctgaacaactgaagcggtttgatgaatggaaggaactgaagcag
cataaagaattccaggacttgcgggaagtaatggagaagagctccagagaagccttggga
caccaagagaagctaaaagctgagcaccgtcacagagcaaagattctcaacctgaagctg
cgggaagcagagcagcagcgcgtgaagcaagcagaacaggagcggcttcggaaggaagaa
ggccagatccgcctgcgggccctctatgctctgcaggaggagatgctgcagctcagccag
cagctggatgcctctgagcagcacaaagccctgcttaaggtcgacctggctgccttccag
acccgaggcaaccagctgtgcagcctcatctcagggatcatccgggcctcttcagagagc
agctatcccacagcagagagtcaagctgaggctgagcgagctctgcgggaaatgcgggac
ctcctgatgaacttggggcaggagatcaccagagcctgcgaagacaagaggaggcaggat
gaagaagaggcccaggtaaagctgcaagaggcacagatgcagcagggaccagaggcccac
aaagagcccccagctcccagccagggcccaggagggaaacagaatgaagacctccaggtg
aaggtacaagacattacaatgcagtggtaccagcagctgcaggatgcttccatgcagtgt
gtgttgacctttgagggcctgaccaacagcaaggacagtcaggccaaaaagataaagatg
gacctccagaaggctgctaccatcccagtgagccaaatctctaccattgcaggctcaaaa
ctgaaggagatctttgacaagatccacagcctgctctctggaaaacctgttcaatctggt
gggcgctctgtgtctgtcacacttaacccacaggggctggactttgttcaatacaaactg
gcagagaaatttgtgaaacaaggcgaggaggaagtggcctctcaccatgaagcagcattc
cccattgcagttgtggcatccgggatctgggagctccaccccagagtgggggacctcatt
cttgctcatctacataagaagtgtccttactctgttcctttctatcccactttcaaggag
ggaatggctttggaagactatcagaggatgcttggttaccaagtaaaggattccaaagtg
gagcagcaagacaactttctaaaacgcatgtcagggatgatccgtctctacgctgctatc
atccagctccggtggccatatggaaaccgacaggagattcaccctcatggcttaaatcat
ggatggcgctggttggcacagatcttaaacatggagcccttgtcagatgtgacagccacc
ctcctctttgacttcctggaggtgtgtgggaatgccctcatgaagcaataccaggttcag
ttctggaagatgctaattctcatcaaagaggactactttcccagaattgaagctatcaca
agctcaggacagatgggctccttcatacgcctcaagcagttcttggagaaatgtttgcaa
cacaaggacattcctgtccccaagggctttctgacttcctccttctggcgctcctga
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