Homo sapiens (human): 283748 Help Entry 283748            CDS       T01001                                  Symbol PLA2G4D, cPLA2delta Name (RefSeq) phospholipase A2 group IVD   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04010   MAPK signaling pathway hsa04014   Ras signaling pathway hsa04072   Phospholipase D signaling pathway hsa04217   Necroptosis hsa04270   Vascular smooth muscle contraction hsa04370   VEGF signaling pathway hsa04611   Platelet activation hsa04664   Fc epsilon RI signaling pathway hsa04666   Fc gamma R-mediated phagocytosis hsa04724   Glutamatergic synapse hsa04726   Serotonergic synapse hsa04730   Long-term depression hsa04750   Inflammatory mediator regulation of TRP channels hsa04912   GnRH signaling pathway hsa04913   Ovarian steroidogenesis hsa04921   Oxytocin signaling pathway hsa05231   Choline metabolism in cancer Network nt06544  Neuroactive ligand signaling   Element N01900   Serotonin-HTR2-GNAQ/11 signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     283748 (PLA2G4D)    00565 Ether lipid metabolism     283748 (PLA2G4D)    00590 Arachidonic acid metabolism     283748 (PLA2G4D)    00591 Linoleic acid metabolism     283748 (PLA2G4D)    00592 alpha-Linolenic acid metabolism     283748 (PLA2G4D)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     283748 (PLA2G4D)    04072 Phospholipase D signaling pathway     283748 (PLA2G4D)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     283748 (PLA2G4D)    04664 Fc epsilon RI signaling pathway     283748 (PLA2G4D)    04666 Fc gamma R-mediated phagocytosis     283748 (PLA2G4D)   09152 Endocrine system    04913 Ovarian steroidogenesis     283748 (PLA2G4D)    04921 Oxytocin signaling pathway     283748 (PLA2G4D)   09156 Nervous system    04724 Glutamatergic synapse     283748 (PLA2G4D)    04726 Serotonergic synapse     283748 (PLA2G4D)    04730 Long-term depression     283748 (PLA2G4D)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     283748 (PLA2G4D)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     283748 (PLA2G4D) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      283748 (PLA2G4D) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 Motif Other DBs NCBI-GeneID:  283748 NCBI-ProteinID:  NP_828848 OMIM:  612864 HGNC:  30038 Ensembl:  ENSG00000159337 UniProt:  Q86XP0 Structure PDBPDBj LinkDB All DBs Position 15:complement(42067009..42094562) Genome browser AA seq 818 aa AA seqDB search MESLSPGGPPGHPYQGEASTCWQLTVRVLEARNLRWADLLSEADPYVILQLSTAPGMKFK TKTLTDTSHPVWNEAFRFLIQSQVKNVLELSIYDEDSVTEDDICFKVLYDISEVLPGKLL RKTFSQSPQGEEELDVEFLMEETSDRPENLITNKVIVARELSCLDVHLDSTGSTAVVADQ DKLELELVLKGSYEDTQTSFLGTASAFRFHYMAALETELSGRLRSSRSNGWNGDNSAGYL TVPLRPLTIGKEVTMDVPAPNAPGVRLQLKAEGCPEELAVHLGFNLCAEEQAFLSRRKQV VAKALKQALQLDRDLQEDEVPVVGIMATGGGARAMTSLYGHLLALQKLGLLDCVTYFSGI SGSTWTMAHLYGDPEWSQRDLEGPIRYAREHLAKSKLEVFSPERLASYRRELELRAEQGH PTTFVDLWALVLESMLHGQVMDQKLSGQRAALERGQNPLPLYLSLNVKENNLETLDFKEW VEFSPYEVGFLKYGAFVPPELFGSEFFMGRLMRRIPEPRICFLEAIWSNIFSLNLLDAWY DLTSSGESWKQHIKDKTRSLEKEPLTTSGTSSRLEASWLQPGTALAQAFKGFLTGRPLHQ RSPNFLQGLQLHQDYCSHKDFSTWADYQLDSMPSQLTPKEPRLCLVDAAYFINTSSPSMF RPGRRLDLILSFDYSLSAPFEALQQTELYCRARGLPFPRVEPSPQDQHQPRECHLFSDPA CPEAPILLHFPLVNASFKDHSAPGVQRSPAELQGGQVDLTGATCPYTLSNMTYKEEDFER LLRLSDYNVQTSQGAILQALRTALKHRTLEARPPRAQT NT seq 2457 nt NT seq  +upstreamnt  +downstreamnt atggagagcctgtcacctgggggaccacctggccacccttaccagggggaggcctctacc tgctggcagctcacagtgagggtcctggaggcgcggaacctgcgctgggctgacctgttg agtgaggccgacccttacgtgatcctacagctgtcgaccgcacctggaatgaagtttaag accaagacgctcaccgacaccagtcatcctgtgtggaatgaggccttccgtttccttatc caaagtcaggtcaagaatgttctggagcttagcatctatgatgaggactcagtcacggag gatgacatctgcttcaaggttctctatgacatctcagaagtcctccctggcaagctgctc cggaaaaccttctcccagagtccccagggagaggaggagctggatgtggagttcctgatg gaagaaacgtcagatcgcccagaaaacctcatcaccaacaaagtcattgtggcccgagag ctgtcatgcctggatgtgcatctggacagcacagggagcaccgctgtggttgcagatcag gacaagctggagctggagctggtgctgaaggggtcctatgaggacacacagacatccttc ctgggcacagcctctgccttccgcttccactacatggcagccctagagacagagctgagc gggcgcctgaggagctccagaagcaatggctggaatggggacaactcagctgggtacctc actgtgcccctgaggcccttgaccattgggaaggaggtgactatggatgttcctgctcca aatgccccaggagtgaggctgcagctcaaggcagagggctgccctgaggagctggccgtg cacctgggcttcaatctctgtgcagaggagcaggccttcctgagcaggaggaagcaggtg gtggccaaggccctgaagcaggccctgcagctggacagagacctgcaggaggatgaggta cccgttgtgggcatcatggccacaggaggaggtgcccgggccatgacctcactctacggc cacctattggccttgcagaagctgggcctcctagactgtgtgacctacttcagtggcatc tctggctctacgtggacaatggcccacctgtacggggaccctgagtggtcgcagagggac ctggagggacctatcagatacgcccgggagcacctggccaagagcaagctggaggtcttt tccccagagcgcctggcgagctaccgccgggagctggagctgcgggctgagcagggccac cccacgacctttgtggacctgtgggcgctagtgctggagtccatgctgcacggccaggtg atggatcagaagctgtcaggacagagagccgccctggaacggggtcagaaccctctgccc ctctacttgagcctcaatgtcaaagagaacaatctggagacactggacttcaaggagtgg gttgagttctccccctatgaggtcggtttcctgaagtacggggccttcgtccctcctgag ctcttcggctccgagttcttcatgggacggctgatgaggaggatcccggagccccggatc tgctttctggaagccatctggagcaacattttctccctgaacctgctggatgcctggtat gacctcaccagttctggggagtcctggaaacagcacatcaaggacaagaccaggagctta gagaaggagcccctgaccacctcggggacctcctcgcggctggaggcctcgtggctgcag ccaggcacggcgctggcccaggcatttaaaggcttcctgacaggcaggcccctccaccag cgcagccccaacttcctccagggcctccagctgcaccaggactactgtagccacaaagac ttctccacctgggcagactaccagcttgactccatgcccagccagctgacccccaaggag ccccggctctgcctggtggacgccgcctacttcatcaacaccagctctccctccatgttc cggccaggccgcaggctggacctcatcctctccttcgactactccctatctgcgcccttc gaggcactgcagcagacggagctgtactgccgggcccgggggctgcccttcccccgggtg gaacccagccctcaggaccagcaccagccaagggaatgccacctcttctcagaccccgcc tgccccgaggccccgatcctgctgcacttcccgctggtcaatgcctccttcaaggaccac tcagcccccggtgtccagcgcagccccgcagagctccagggtggccaagtggatctcacc ggggccacctgcccctacaccctgtccaacatgacctacaaggaggaagacttcgagcgc ctgctgcggctcagtgactacaacgtgcagaccagccagggtgccatcctgcaggccctg aggaccgcgctgaagcaccggactctagaggcgaggcctccaagggcacagacctga

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