Homo sapiens (human): 2968
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Entry
2968 CDS
T01001
Symbol
GTF2H4, P52, TFB2, TFIIH
Name
(RefSeq) general transcription factor IIH subunit 4
KO
K03144
transcription initiation factor TFIIH subunit 4
Organism
hsa
Homo sapiens (human)
Pathway
hsa03022
Basal transcription factors
hsa03420
Nucleotide excision repair
hsa05203
Viral carcinogenesis
Network
nt06502
Nucleotide excision repair
Element
N01425
Global genome NER
N01430
Transcription-coupled NER
N01431
Core NER reaction
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09121 Transcription
03022 Basal transcription factors
2968 (GTF2H4)
09124 Replication and repair
03420 Nucleotide excision repair
2968 (GTF2H4)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
2968 (GTF2H4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
hsa03021
]
2968 (GTF2H4)
03400 DNA repair and recombination proteins [BR:
hsa03400
]
2968 (GTF2H4)
Transcription machinery [BR:
hsa03021
]
Eukaryotic type
RNA polymerase II system
Basal transcription factors
TFIIH
2968 (GTF2H4)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
SSBR (single strand breaks repair)
NER (nucleotide excision repair)
TFIIH complex
2968 (GTF2H4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Tfb2
Tfb2_C
Helicase_C_3
Motif
Other DBs
NCBI-GeneID:
2968
NCBI-ProteinID:
NP_001508
OMIM:
601760
HGNC:
4658
Ensembl:
ENSG00000213780
UniProt:
Q92759
A0A1U9X7S4
Structure
PDB
PDBj
LinkDB
All DBs
Position
6:30908207..30914106
Genome browser
AA seq
462 aa
AA seq
DB search
MESTPSRGLNRVHLQCRNLQEFLGGLSPGVLDRLYGHPATCLAVFRELPSLAKNWVMRML
FLEQPLPQAAVALWVKKEFSKAQEESTGLLSGLRIWHTQLLPGGLQGLILNPIFRQNLRI
ALLGGGKAWSDDTSQLGPDKHARDVPSLDKYAEERWEVVLHFMVGSPSAAVSQDLAQLLS
QAGLMKSTEPGEPPCITSAGFQFLLLDTPAQLWYFMLQYLQTAQSRGMDLVEILSFLFQL
SFSTLGKDYSVEGMSDSLLNFLQHLREFGLVFQRKRKSRRYYPTRLAINLSSGVSGAGGT
VHQPGFIVVETNYRLYAYTESELQIALIALFSEMLYRFPNMVVAQVTRESVQQAIASGIT
AQQIIHFLRTRAHPVMLKQTPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFEL
LLAHARELGVLVFENSAKRLMVVTPAGHSDVKRFWKRQKHSS
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atggagagcaccccttcaaggggactgaaccgagtacacctacaatgcaggaatctgcag
gaattcttagggggcctgagccctggggtattggaccgattgtatgggcaccctgccaca
tgtctggctgtcttcagggagctcccatccttggctaagaactgggtgatgcggatgctc
tttctggagcagcctttgccacaggctgctgtagctctgtgggtaaagaaggaattcagc
aaggctcaggaggaaagtacagggctgctgagcggcctccggatctggcacacacagctg
ctcccaggcgggctccagggcctcatcctcaaccccattttccgccagaacctccgcatt
gcccttctgggtggggggaaggcctggtctgatgacacaagtcagctgggaccagacaag
catgcccgggacgttccctcccttgacaagtacgccgaggagcgatgggaggtggtcttg
cacttcatggtgggctcccccagtgcagctgtcagccaggacttggctcagctcctcagc
caggctgggctcatgaagagtactgaacctggagagccgccctgcattacttccgctggc
ttccagttcctgttgctggacaccccggctcagctctggtactttatgttgcagtatttg
cagacagcccagagccggggcatggacctggtagagattctctccttcctcttccagctc
agcttctctactctgggcaaggattactctgtggaaggtatgagtgattctctgttgaac
ttcctgcaacatctgcgtgagtttgggcttgttttccagaggaagaggaaatctcggcgt
tactaccccacacgcctggccatcaatctctcatcaggtgtctctggagctgggggcact
gtgcatcagccaggtttcattgtcgtggaaaccaattaccgactgtatgcctacacggag
tcggagctgcagattgccctcattgccctcttctctgagatgctctatcggttccccaac
atggtggtggcgcaggtgacccgggagagtgtgcagcaggcaatcgccagtggcatcaca
gcccagcagataatccatttcctaaggacaagagcccacccagtgatgctcaaacagaca
cctgtgctgccccccaccatcaccgaccagatccggctctgggagctggaaagggacaga
ctccggttcactgagggtgtcctgtataaccagttcctgtcgcaagtggactttgagctg
ctgctggcccacgcgcgggagctgggcgtgctcgtgttcgagaactcggccaagcggctc
atggtggtgaccccggccgggcacagcgacgtcaagcgcttttggaagcggcagaaacat
agctcctga
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