KEGG   Homo sapiens (human): 2968
Entry
2968              CDS       T01001                                 
Symbol
GTF2H4, P52, TFB2, TFIIH
Name
(RefSeq) general transcription factor IIH subunit 4
  KO
K03144  transcription initiation factor TFIIH subunit 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa03022  Basal transcription factors
hsa03420  Nucleotide excision repair
hsa05203  Viral carcinogenesis
Network
nt06502  Nucleotide excision repair
  Element
N01425  Global genome NER
N01430  Transcription-coupled NER
N01431  Core NER reaction
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03022 Basal transcription factors
    2968 (GTF2H4)
  09124 Replication and repair
   03420 Nucleotide excision repair
    2968 (GTF2H4)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    2968 (GTF2H4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    2968 (GTF2H4)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    2968 (GTF2H4)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Basal transcription factors
    TFIIH
     2968 (GTF2H4)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TFIIH complex
     2968 (GTF2H4)
SSDB
Motif
Pfam: Tfb2 Tfb2_C Helicase_C_3
Other DBs
NCBI-GeneID: 2968
NCBI-ProteinID: NP_001508
OMIM: 601760
HGNC: 4658
Ensembl: ENSG00000213780
UniProt: Q92759 A0A1U9X7S4
Structure
LinkDB
Position
6:30908207..30914106
AA seq 462 aa
MESTPSRGLNRVHLQCRNLQEFLGGLSPGVLDRLYGHPATCLAVFRELPSLAKNWVMRML
FLEQPLPQAAVALWVKKEFSKAQEESTGLLSGLRIWHTQLLPGGLQGLILNPIFRQNLRI
ALLGGGKAWSDDTSQLGPDKHARDVPSLDKYAEERWEVVLHFMVGSPSAAVSQDLAQLLS
QAGLMKSTEPGEPPCITSAGFQFLLLDTPAQLWYFMLQYLQTAQSRGMDLVEILSFLFQL
SFSTLGKDYSVEGMSDSLLNFLQHLREFGLVFQRKRKSRRYYPTRLAINLSSGVSGAGGT
VHQPGFIVVETNYRLYAYTESELQIALIALFSEMLYRFPNMVVAQVTRESVQQAIASGIT
AQQIIHFLRTRAHPVMLKQTPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFEL
LLAHARELGVLVFENSAKRLMVVTPAGHSDVKRFWKRQKHSS
NT seq 1389 nt   +upstreamnt  +downstreamnt
atggagagcaccccttcaaggggactgaaccgagtacacctacaatgcaggaatctgcag
gaattcttagggggcctgagccctggggtattggaccgattgtatgggcaccctgccaca
tgtctggctgtcttcagggagctcccatccttggctaagaactgggtgatgcggatgctc
tttctggagcagcctttgccacaggctgctgtagctctgtgggtaaagaaggaattcagc
aaggctcaggaggaaagtacagggctgctgagcggcctccggatctggcacacacagctg
ctcccaggcgggctccagggcctcatcctcaaccccattttccgccagaacctccgcatt
gcccttctgggtggggggaaggcctggtctgatgacacaagtcagctgggaccagacaag
catgcccgggacgttccctcccttgacaagtacgccgaggagcgatgggaggtggtcttg
cacttcatggtgggctcccccagtgcagctgtcagccaggacttggctcagctcctcagc
caggctgggctcatgaagagtactgaacctggagagccgccctgcattacttccgctggc
ttccagttcctgttgctggacaccccggctcagctctggtactttatgttgcagtatttg
cagacagcccagagccggggcatggacctggtagagattctctccttcctcttccagctc
agcttctctactctgggcaaggattactctgtggaaggtatgagtgattctctgttgaac
ttcctgcaacatctgcgtgagtttgggcttgttttccagaggaagaggaaatctcggcgt
tactaccccacacgcctggccatcaatctctcatcaggtgtctctggagctgggggcact
gtgcatcagccaggtttcattgtcgtggaaaccaattaccgactgtatgcctacacggag
tcggagctgcagattgccctcattgccctcttctctgagatgctctatcggttccccaac
atggtggtggcgcaggtgacccgggagagtgtgcagcaggcaatcgccagtggcatcaca
gcccagcagataatccatttcctaaggacaagagcccacccagtgatgctcaaacagaca
cctgtgctgccccccaccatcaccgaccagatccggctctgggagctggaaagggacaga
ctccggttcactgagggtgtcctgtataaccagttcctgtcgcaagtggactttgagctg
ctgctggcccacgcgcgggagctgggcgtgctcgtgttcgagaactcggccaagcggctc
atggtggtgaccccggccgggcacagcgacgtcaagcgcttttggaagcggcagaaacat
agctcctga

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