KEGG   Homo sapiens (human): 3060
Entry
3060              CDS       T01001                                 
Symbol
HCRT, NRCLP1, OX, PPOX
Name
(RefSeq) hypocretin neuropeptide precursor
  KO
K05246  hypocretin (orexin) neuropeptide
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04081  Hormone signaling
Network
nt06325  Hormone/cytokine signaling
  Element
N01794  HCRT-HCRTR signaling pathway
Disease
H01293  Narcolepsy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    3060 (HCRT)
   04081 Hormone signaling
    3060 (HCRT)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    3060 (HCRT)
Cytokines and neuropeptides [BR:hsa04052]
 Neuropeptides
  GPCR binding
   3060 (HCRT)
SSDB
Motif
Pfam: Orexin
Other DBs
NCBI-GeneID: 3060
NCBI-ProteinID: NP_001515
OMIM: 602358
HGNC: 4847
Ensembl: ENSG00000161610
CPD: C16105 C16106
UniProt: O43612
Structure
LinkDB
Position
17:complement(42184060..42185452)
AA seq 131 aa
MNLPSTKVSWAAVTLLLLLLLLPPALLSSGAAAQPLPDCCRQKTCSCRLYELLHGAGNHA
AGILTLGKRRSGPPGLQGRLQRLLQASGNHAAGILTMGRRAGAEPAPRPCLGRRCSAPAA
ASVAPGGQSGI
NT seq 396 nt   +upstreamnt  +downstreamnt
atgaaccttccttccacaaaggtctcctgggccgccgtgacgctactgctgctgctgctg
ctgctgccgcccgcgctgttgtcgtccggggcggctgcacagcccctgcccgactgctgt
cgtcaaaagacttgctcttgccgcctctacgagctgctgcacggcgcgggcaatcacgcg
gccggcatcctcacgctgggcaagcggaggtccgggcccccgggcctccagggtcggctg
cagcgcctcctgcaggccagcggcaaccacgccgcgggcatcctgaccatgggccgccgc
gcaggcgcagagccagcgccgcgcccctgcctcgggcgccgctgttccgccccggccgcc
gcctccgtcgcgcccggaggacagtccgggatctga

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