Homo sapiens (human): 3101 Help Entry 3101              CDS       T01001                                  Symbol HK3, HKIII, HXK3 Name (RefSeq) hexokinase 3   KO K00844   hexokinase [EC:2.7.1.1] Organism hsa  Homo sapiens (human) Pathway hsa00010   Glycolysis / Gluconeogenesis hsa00051   Fructose and mannose metabolism hsa00052   Galactose metabolism hsa00500   Starch and sucrose metabolism hsa00520   Amino sugar and nucleotide sugar metabolism hsa00524   Neomycin, kanamycin and gentamicin biosynthesis hsa01100   Metabolic pathways hsa01200   Carbon metabolism hsa01250   Biosynthesis of nucleotide sugars hsa04066   HIF-1 signaling pathway hsa04910   Insulin signaling pathway hsa04930   Type II diabetes mellitus hsa04973   Carbohydrate digestion and absorption hsa05131   Shigellosis hsa05230   Central carbon metabolism in cancer Module hsa_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate hsa_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Network nt06524  Apoptosis   Element N00950   Shigella FimA to crosstalk between extrinsic and intrinsic apoptotic pathways Drug target Lonidamine:  D07257 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     3101 (HK3)    00051 Fructose and mannose metabolism     3101 (HK3)    00052 Galactose metabolism     3101 (HK3)    00500 Starch and sucrose metabolism     3101 (HK3)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     3101 (HK3)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     3101 (HK3)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     3101 (HK3)  09150 Organismal Systems   09154 Digestive system    04973 Carbohydrate digestion and absorption     3101 (HK3)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     3101 (HK3)   09171 Infectious disease: bacterial    05131 Shigellosis     3101 (HK3)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     3101 (HK3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     3101 (HK3) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      3101 (HK3) Membrane trafficking [BR:hsa04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     3101 (HK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 DUF5473 Motif Other DBs NCBI-GeneID:  3101 NCBI-ProteinID:  NP_002106 OMIM:  142570 HGNC:  4925 Ensembl:  ENSG00000160883 UniProt:  P52790 Structure PDBPDBj LinkDB All DBs Position 5:complement(176880869..176899346) Genome browser AA seq 923 aa AA seqDB search MDSIGSSGLRQGEETLSCSEEGLPGPSDSSELVQECLQQFKVTRAQLQQIQASLLGSMEQ ALRGQASPAPAVRMLPTYVGSTPHGTEQGDFVVLELGATGASLRVLWVTLTGIEGHRVEP RSQEFVIPQEVMLGAGQQLFDFAAHCLSEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRST LISWTKGFRCSGVEGQDVVQLLRDAIRRQGAYNIDVVAVVNDTVGTMMGCEPGVRPCEVG LVVDTGTNACYMEEARHVAVLDEDRGRVCVSVEWGSFSDDGALGPVLTTFDHTLDHESLN PGAQRFEKMIGGLYLGELVRLVLAHLARCGVLFGGCTSPALLSQGSILLEHVAEMEDPST GAARVHAILQDLGLSPGASDVELVQHVCAAVCTRAAQLCAAALAAVLSCLQHSREQQTLQ VAVATGGRVCERHPRFCSVLQGTVMLLAPECDVSLIPSVDGGGRGVAMVTAVAARLAAHR RLLEETLAPFRLNHDQLAAVQAQMRKAMAKGLRGEASSLRMLPTFVRATPDGSERGDFLA LDLGGTNFRVLLVRVTTGVQITSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLSGQ SLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAVELNVVAI VNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPGDSGRMCINMEWGAFGD DGSLAMLSTRFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQQIQ RLQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLPLTSDDALMVLEVCQAVSQRAAQLC GAGVAAVVEKIRENRGLEELAVSVGVDGTLYKLHPRFSSLVAATVRELAPRCVVTFLQSE DGSGKGAALVTAVACRLAQLTRV NT seq 2772 nt NT seq  +upstreamnt  +downstreamnt atggactccattgggtcttcagggttgcggcagggggaagaaaccctgagttgctctgag gagggcttgcccgggccctcagacagctcagagctggtgcaggagtgcctgcagcagttc aaggtgacaagggcacagctacagcagatccaagccagcctcttgggttccatggagcag gcgctgaggggacaggccagccctgcccctgcggtccggatgctgcctacatacgtgggg tccaccccacatggcactgagcaaggagacttcgtggtgctggagctgggggccacaggg gcctcactgcgtgttttgtgggtgactctaactggcattgaggggcatagggtggagccc agaagccaggagtttgtgatcccccaagaggtgatgctgggtgctggccagcagctcttt gactttgctgcccactgcctgtctgagttcctggatgcgcagcctgtgaacaaacagggt ctgcagcttggcttcagcttctctttcccttgtcaccagacgggcttggacaggagcacc ctcatttcctggaccaaaggttttaggtgcagtggtgtggaaggccaggatgtggtccag ctgctgagagatgccattcggaggcagggggcctacaacatcgacgtggttgctgtggtg aacgacacagtgggcaccatgatgggctgtgagccgggggtcaggccgtgtgaggttggg ctagttgtagacacgggcaccaacgcgtgttacatggaggaggcacggcatgtggcagtg ctggacgaagaccggggccgcgtctgcgtcagcgtcgagtggggctccttcagcgatgat ggggcgctgggaccagtgctgaccaccttcgaccataccctggaccatgagtccctgaat cctggtgctcagaggtttgagaagatgatcggaggcctgtacctgggtgagctggtgcgg ctggtgctggctcacttggcccggtgtggggtcctctttggtggctgcacctcccctgcc ctgctgagccaaggcagcatcctcctggaacacgtggctgagatggaggacccctctact ggggcagcccgtgtccatgctatcctgcaggacttgggcctgagccctggggcttcggat gttgagcttgtgcagcacgtctgtgcggccgtgtgcacgcgggctgcccagctctgtgct gccgccctggccgctgttctctcctgcctccagcacagccgggagcaacaaacactccag gttgctgtggccaccggaggccgagtgtgtgagcggcaccccaggttctgcagcgtcctg caggggacagtgatgctcctggccccggaatgcgatgtctccttaatcccctctgtggat ggtggtggccggggagtggcgatggtgactgccgtggctgcccgtctggctgcccaccgg cgcctgctggaggagaccctggccccattccggttgaaccatgatcaactggctgcggtt caggcacagatgcggaaggccatggccaaggggctccgaggggaggcctcctcccttcgc atgctgcccactttcgtccgggccacccctgacggcagcgagcgaggggatttcctggcc ctggacctcgggggcacgaacttccgtgtcctcctggtacgtgtgaccacaggcgtgcag atcaccagcgagatctactccattcccgagactgtggcccagggttctgggcagcagctc tttgaccacatcgtggactgcatcgtggacttccagcagaagcagggcctgagcgggcag agcctcccactgggttttaccttctccttcccatgtaggcagcttggcctagaccagggc atcctcctgaactggaccaagggtttcaaggcatcagactgcgagggccaagatgtcgtg agtctgttgcgggaagccatcactcgcagacaggcagtggagctgaatgtggttgccatt gtcaatgacacggtggggaccatgatgtcctgtggctatgaggacccccgttgcgagata ggcctcattgtcggaaccggcaccaatgcctgctacatggaggagctccggaatgtggcg ggcgtgcctggggactcaggccgcatgtgcatcaacatggagtggggcgcctttggggac gatggctctctggccatgctcagcacccgctttgatgcaagtgtggaccaggcgtccatc aaccccggcaagcagaggtttgaaaagatgatcagcggcatgtacctgggggagatcgtc cgccacatccttttacatttaaccagccttggcgttctcttccggggccagcagatccag cgccttcagaccagggacatcttcaagaccaagttcctctctgagatcgaaagtgacagc ctggccctgcggcaggtccgagccatcctagaggatctggggctacccctgacctcagat gacgccctgatggtgctagaggtgtgccaggctgtgtcccagagggctgcccagctctgt ggggcgggtgtagctgccgtggtggagaagatccgggagaaccggggcctggaagagctg gcagtgtctgtgggggtggatggaacgctctacaagctgcacccgcgcttctccagcctg gtggcggccacagtgcgggagctggcccctcgctgtgtggtcacgttcctgcagtcagag gatgggtccggcaaaggtgcggccctggtcaccgctgttgcctgccgccttgcgcagttg actcgtgtctga

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