Homo sapiens (human): 3127
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Entry
3127 CDS
T01001
Symbol
HLA-DRB5, DRB5, HLA-DRB5*
Name
(RefSeq) major histocompatibility complex, class II, DR beta 5
KO
K06752
MHC class II antigen
Organism
hsa
Homo sapiens (human)
Pathway
hsa04145
Phagosome
hsa04514
Cell adhesion molecules
hsa04612
Antigen processing and presentation
hsa04640
Hematopoietic cell lineage
hsa04658
Th1 and Th2 cell differentiation
hsa04659
Th17 cell differentiation
hsa04672
Intestinal immune network for IgA production
hsa04940
Type I diabetes mellitus
hsa05140
Leishmaniasis
hsa05145
Toxoplasmosis
hsa05150
Staphylococcus aureus infection
hsa05152
Tuberculosis
hsa05164
Influenza A
hsa05166
Human T-cell leukemia virus 1 infection
hsa05168
Herpes simplex virus 1 infection
hsa05169
Epstein-Barr virus infection
hsa05310
Asthma
hsa05320
Autoimmune thyroid disease
hsa05321
Inflammatory bowel disease
hsa05322
Systemic lupus erythematosus
hsa05323
Rheumatoid arthritis
hsa05330
Allograft rejection
hsa05332
Graft-versus-host disease
hsa05416
Viral myocarditis
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06168
Herpes simplex virus 1 (HSV-1)
Element
N00508
HTLV-1 Tax to NFY-mediated transcription
N00590
Antigen processing and presentation by MHC class II molecules
Disease
H02424
Primary central nervous system lymphoma
Drug target
Apolizumab:
D02967
Glatiramer acetate:
D04318
<JP/US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
3127 (HLA-DRB5)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
3127 (HLA-DRB5)
04612 Antigen processing and presentation
3127 (HLA-DRB5)
04658 Th1 and Th2 cell differentiation
3127 (HLA-DRB5)
04659 Th17 cell differentiation
3127 (HLA-DRB5)
09160 Human Diseases
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
3127 (HLA-DRB5)
05164 Influenza A
3127 (HLA-DRB5)
05169 Epstein-Barr virus infection
3127 (HLA-DRB5)
09171 Infectious disease: bacterial
05150 Staphylococcus aureus infection
3127 (HLA-DRB5)
05152 Tuberculosis
3127 (HLA-DRB5)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
3127 (HLA-DRB5)
05140 Leishmaniasis
3127 (HLA-DRB5)
09163 Immune disease
05310 Asthma
3127 (HLA-DRB5)
05322 Systemic lupus erythematosus
3127 (HLA-DRB5)
05323 Rheumatoid arthritis
3127 (HLA-DRB5)
05320 Autoimmune thyroid disease
3127 (HLA-DRB5)
05321 Inflammatory bowel disease
3127 (HLA-DRB5)
05330 Allograft rejection
3127 (HLA-DRB5)
05332 Graft-versus-host disease
3127 (HLA-DRB5)
09166 Cardiovascular disease
05416 Viral myocarditis
3127 (HLA-DRB5)
09167 Endocrine and metabolic disease
04940 Type I diabetes mellitus
3127 (HLA-DRB5)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
3127 (HLA-DRB5)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
3127 (HLA-DRB5)
Exosomal proteins of epithelial cells
3127 (HLA-DRB5)
Exosomal proteins of breast milk
3127 (HLA-DRB5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MHC_II_beta
C1-set
ig
Ig_2
C2-set_3
Motif
Other DBs
NCBI-GeneID:
3127
NCBI-ProteinID:
NP_002116
OMIM:
604776
HGNC:
4953
Ensembl:
ENSG00000198502
UniProt:
Q30154
A0A2Z4LKS3
Structure
PDB
PDBj
LinkDB
All DBs
Position
6:complement(32517353..32530287)
Genome browser
AA seq
266 aa
AA seq
DB search
MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI
YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV
QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL
FLGAGLFIYFKNQKGHSGLHPTGLVS
NT seq
801 nt
NT seq
+upstream
nt +downstream
nt
atggtgtgtctgaagctccctggaggttcctacatggcaaagctgacagtgacactgatg
gtgctgagctccccactggctttggctggggacacccgaccacgtttcttgcagcaggat
aagtatgagtgtcatttcttcaacgggacggagcgggtgcggttcctgcacagagacatc
tataaccaagaggaggacttgcgcttcgacagcgacgtgggggagtaccgggcggtgacg
gagctggggcggcctgacgctgagtactggaacagccagaaggacttcctggaagacagg
cgcgccgcggtggacacctactgcagacacaactacggggttggtgagagcttcacagtg
cagcggcgagttgagcctaaggtgactgtgtatcctgcaaggacccagaccctgcagcac
cacaacctcctggtctgctctgtgaatggtttctatccaggcagcattgaagtcaggtgg
ttccggaacagccaggaagagaaggctggggtggtgtccacaggcctgattcagaatgga
gactggaccttccagaccctggtgatgctggaaacagttcctcgaagtggagaggtttac
acctgccaagtggagcacccaagcgtgacgagccctctcacagtggaatggagagcacag
tctgaatctgcacagagcaagatgctgagtggagtcgggggctttgtgctgggcctgctc
ttccttggggccgggctattcatctacttcaagaatcagaaagggcactctggacttcac
ccaacaggactcgtgagctga
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integrated database retrieval system
