Homo sapiens (human): 314 Help Entry 314               CDS       T01001                                  Symbol AOC2, DAO2, RAO, SSAO Name (RefSeq) amine oxidase copper containing 2   KO K00276   primary-amine oxidase [EC:1.4.3.21] Organism hsa  Homo sapiens (human) Pathway hsa00260   Glycine, serine and threonine metabolism hsa00350   Tyrosine metabolism hsa00360   Phenylalanine metabolism hsa00410   beta-Alanine metabolism hsa01100   Metabolic pathways Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00260 Glycine, serine and threonine metabolism     314 (AOC2)    00350 Tyrosine metabolism     314 (AOC2)    00360 Phenylalanine metabolism     314 (AOC2)   09106 Metabolism of other amino acids    00410 beta-Alanine metabolism     314 (AOC2) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.4  Acting on the CH-NH2 group of donors    1.4.3  With oxygen as acceptor     1.4.3.21  primary-amine oxidase      314 (AOC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Cu_amine_oxid Cu_amine_oxidN3 Cu_amine_oxidN2 DUF1965 bMG6 NPR1_interact Motif Other DBs NCBI-GeneID:  314 NCBI-ProteinID:  NP_033720 OMIM:  602268 HGNC:  549 Ensembl:  ENSG00000131480 UniProt:  O75106 LinkDB All DBs Position 17:42844580..42850707 Genome browser AA seq 756 aa AA seqDB search MHLKIVLAFLALSLITIFALAYVLLTSPGGSSQPPHCPSVSHRAQPWPHPGQSQLFADLS REELTAVMRFLTQRLGPGLVDAAQAQPSDNCIFSVELQLPPKAAALAHLDRGSPPPAREA LAIVLFGGQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLRAEFTQMWRHLK EVELPKAPIFLSSTFNYNGSTLAAVHATPRGLRSGDRATWMALYHNISGVGLFLHPVGLE LLLDHRALDPAHWTVQQVFYLGHYYADLGQLEREFKSGRLEVVRVPLPPPNGASSLRSRN SPGPLPPLQFSPQGSQYSVQGNLVVSSLWSFTFGHGVFSGLRIFDVRFQGERIAYEVSVQ ECVSIYGADSPKTMLTRYLDSSFGLGRNSRGLVRGVDCPYQATMVDIHILVGKGAVQLLP GAVCVFEEAQGLPLRRHHNYLQNHFYGGLASSALVVRSVSSVGNYDYIWDFVLYPNGALE GRVHATGYINTAFLKGGEEGLLFGNRVGERVLGTVHTHAFHFKLDLDVAGLKNWVVAEDV VFKPVAAPWNPEHWLQRPQLTRQVLGKEDLTAFSLGSPLPRYLYLASNQTNAWGHQRGYR IQIHSPLGIHIPLESDMERALSWGRYQLVVTQRKEEESQSSSIYHQNDIWTPTVTFADFI NNETLLGEDLVAWVTASFLHIPHAEDIPNTVTLGNRVGFLLRPYNFFDEDPSIFSPGSVY FEKGQDAGLCSINPVACLPDLAACVPDLPPFSYHGF NT seq 2271 nt NT seq  +upstreamnt  +downstreamnt atgcatctcaagatagtcctggcgttcctggcactgtccctcattaccatctttgccctg gcctatgttttgctgaccagcccaggtggttccagccagcctccccactgcccctctgta tcccatagggcccagccctggccacaccctggccagagccagctgtttgcagacctgagc cgagaggagttgacagctgtgatgcgctttctgacccagcggctggggccagggctggtg gacgcagcccaggctcagccctcggacaactgcatcttctcagtggagctgcagctgccc cccaaggctgcagccctggcccacctggacagggggagccccccacctgcccgggaggca ctggccatcgtcctctttggtggacaaccccaacccaatgtgagtgagctggtggtgggg ccgctgcctcacccctcgtacatgcgggatgtgactgtggagcgtcacggcgggcccctg ccctatcaccgtcgcccggtgctgagagctgagtttacacagatgtggaggcatctgaaa gaggtggagctacccaaggcacccatcttcctgtcgtccaccttcaactacaatggctct accctggcagctgtgcatgccacccctcggggcttgcgctcaggggaccgagctacctgg atggccctctaccataacatctcaggggttggtcttttccttcaccccgtggggctggag ctactactggaccacagggccctggaccctgcccactggactgtccagcaggtcttctac cttgggcactactatgcagacttgggccagttggaacgggagtttaagtctggccggttg gaagtggttagagtccctctacctccaccaaatggagcttcatccctgaggtctcggaac tctccaggtcctcttccccctcttcagttctcgccccagggttcccagtacagtgtgcaa ggaaacctggtggtatcctccctctggtcatttacctttggccatggggtgttcagcggc ctgaggatttttgatgttcggttccagggtgagcgaatagcctatgaagtcagtgtccag gagtgtgtatctatctatggtgccgattcacccaagacgatgctgactcgctatttggat agcagctttggactcggccgtaacagccgaggcttggtgcggggagtggactgcccctat caagccacgatggtggacatccatatattagtgggcaaaggggcagtccagctgcttcca ggggctgtgtgtgtatttgaggaagcccagggactgccccttcgaaggcaccacaattac cttcaaaatcatttctatggtggtttggccagctcagcccttgtggtcaggtctgtgtca tctgtgggcaactatgactacatttgggactttgtgttgtacccaaatggggcacttgaa gggcgggtccatgccacgggttatatcaacacagctttcctgaaagggggagaggagggc ctcctctttgggaaccgtgtgggggaaagagtgctgggaacggtgcacacacatgccttc cacttcaagctggacctggatgtggcagggctgaaaaactgggtggtagctgaagacgtg gtgtttaaacctgtggctgccccctggaacccggagcactggctacagcgcccacagctg actcggcaggtcctgggaaaggaggacctgacagctttttccttgggaagccccctaccc cgctacctctacctggctagcaaccagactaatgcgtggggtcaccagcgcgggtaccga atccagatccacagcccccttggcatacacatacccctggagagtgacatggagagggcc ctcagctgggggagataccagcttgtggtgacccagagaaaggaggaggagtcacagagc agtagcatctatcaccagaatgacatctggacacccacagttacctttgctgacttcatc aacaatgaaaccctcttaggagaggatctggtggcttgggtcacagccagcttcctgcac attccccatgccgaggacatcccaaacacagtgactctggggaacagagttggcttcttg ctccgaccctataacttctttgatgaggacccctccatcttctcccctggcagtgtctac tttgagaagggccaggatgctgggctctgcagcatcaatcctgtggcctgcctccccgac ctggcagcctgtgtcccggacttaccccctttctcttaccacggcttctag

Homo sapiens (human): 8639 Help Entry 8639              CDS       T01001                                  Symbol AOC3, HPAO, SSAO, VAP-1, VAP1 Name (RefSeq) amine oxidase copper containing 3   KO K00276   primary-amine oxidase [EC:1.4.3.21] Organism hsa  Homo sapiens (human) Pathway hsa00260   Glycine, serine and threonine metabolism hsa00350   Tyrosine metabolism hsa00360   Phenylalanine metabolism hsa00410   beta-Alanine metabolism hsa01100   Metabolic pathways Drug target Hydralazine (DG00261):  D04458 D08044 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00260 Glycine, serine and threonine metabolism     8639 (AOC3)    00350 Tyrosine metabolism     8639 (AOC3)    00360 Phenylalanine metabolism     8639 (AOC3)   09106 Metabolism of other amino acids    00410 beta-Alanine metabolism     8639 (AOC3) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.4  Acting on the CH-NH2 group of donors    1.4.3  With oxygen as acceptor     1.4.3.21  primary-amine oxidase      8639 (AOC3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Cu_amine_oxid Cu_amine_oxidN2 Cu_amine_oxidN3 DUF1965 Motif Other DBs NCBI-GeneID:  8639 NCBI-ProteinID:  NP_003725 OMIM:  603735 HGNC:  550 Ensembl:  ENSG00000131471 UniProt:  Q16853 Q9UEU7 Structure PDBPDBj LinkDB All DBs Position 17:42851199..42858124 Genome browser AA seq 763 aa AA seqDB search MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLF ADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPP AREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDID QMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFL HHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSW SLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLV YEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQ APKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFH PSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVW AEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHP RGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDF SDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSA DSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN NT seq 2292 nt NT seq  +upstreamnt  +downstreamnt atgaaccagaagacaatcctcgtgctcctcattctggccgtcatcaccatctttgccttg gtttgtgtcctgctggtgggcaggggtggagatgggggtgaacccagccagcttccccat tgcccctctgtatctcccagtgcccagccttggacacaccctggccagagccagctgttt gcagacctgagccgagaggagctgacggctgtgatgcgctttctgacccagcggctgggg ccagggctggtggatgcagcccaggcccggccctcggacaactgtgtcttctcagtggag ttgcagctgcctcccaaggctgcagccctggctcacttggacagggggagccccccacct gcccgggaggcactggccatcgtcttctttggcaggcaaccccagcccaacgtgagtgag ctggtggtggggccactgcctcacccctcctacatgcgggacgtgactgtggagcgtcat ggaggccccctgccctatcaccgacgccccgtgctgttccaagagtacctggacatagac cagatgatcttcaacagagagctgccccaggcttctgggcttctccaccactgttgcttc tacaagcaccggggacggaacctggtgacaatgaccacggctccccgtggtctgcaatca ggggaccgggccacctggtttggcctctactacaacatctcgggcgctgggttcttcctg caccacgtgggcttggagctgctagtgaaccacaaggcccttgaccctgcccgctggact atccagaaggtgttctatcaaggccgctactacgacagcctggcccagctggaggcccag tttgaggccggcctggtgaatgtggtgctgatcccagacaatggcacaggtgggtcctgg tccctgaagtcccctgtgcccccgggtccagctccccctctacagttctatccccaaggc ccccgcttcagtgtccagggaagtcgagtggcctcctcactgtggactttctcctttggc ctcggagcattcagtggcccaaggatctttgacgttcgcttccaaggagaaagactagtt tatgagataagcctccaagaggccttggccatctatggtggaaattccccagcagcaatg acgacccgctatgtggatggaggctttggcatgggcaagtacaccacgcccctgacccgt ggggtggactgcccctacttggccacctacgtggactggcacttccttttggagtcccag gcccccaagacaatacgtgatgccttttgtgtgtttgaacagaaccagggcctccccctg cggcgacaccactcagatctctactcgcactactttgggggtcttgcggaaacggtgctg gtcgtcagatctatgtccaccttgctcaactatgactatgtgtgggatacggtcttccac cccagtggggccatagaaatacgattctatgccacgggctacatcagctcggcattcctc tttggtgctactgggaagtacgggaaccaagtgtcagagcacaccctgggcacggtccac acccacagcgcccacttcaaggtggatctggatgtagcaggactggagaactgggtctgg gccgaggatatggtctttgtccccatggctgtgccctggagccctgagcaccagctgcag aggctgcaggtgacccggaagctgctggagatggaggagcaggccgccttcctcgtggga agcgccacccctcgctacctgtacctggccagcaaccacagcaacaagtggggtcacccc cggggctaccgcatccagatgctcagctttgctggagagccgctgccccaaaacagctcc atggcgagaggcttcagctgggagaggtaccagctggctgtgacccagcggaaggaggag gagcccagtagcagcagcgttttcaatcagaatgacccttgggcccccactgtggatttc agtgacttcatcaacaatgagaccattgctggaaaggatttggtggcctgggtgacagct ggttttctgcatatcccacatgcagaggacattcctaacacagtgactgtggggaacggc gtgggcttcttcctccgaccctataacttctttgacgaagacccctccttctactctgcc gactccatctacttccgaggggaccaggatgctggggcctgcgaggtcaaccccctagct tgcctgccccaggctgctgcctgtgcccccgacctccctgccttctcccacgggggcttc tctcacaactag

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