KEGG   Homo sapiens (human): 3340
Entry
3340              CDS       T01001                                 
Symbol
NDST1, HSST, MRT46, NST1
Name
(RefSeq) N-deacetylase and N-sulfotransferase 1
  KO
K02576  heparan sulfate N-deacetylase/N-sulfotransferase NDST1 [EC:3.5.1.- 2.8.2.8]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
hsa01100  Metabolic pathways
Module
hsa_M00059  Glycosaminoglycan biosynthesis, heparan sulfate backbone
Network
nt06029  Glycosaminoglycan biosynthesis
  Element
N01582  Heparan sulfate biosynthesis
Disease
H00768  Autosomal recessive intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
    3340 (NDST1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    3340 (NDST1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.2  Sulfotransferases
    2.8.2.8  [heparan sulfate]-glucosamine N-sulfotransferase
     3340 (NDST1)
Glycosyltransferases [BR:hsa01003]
 Unclassified
  Sulfotransferases
   3340 (NDST1)
SSDB
Motif
Pfam: HSNSD-CE HSNSD_N Sulfotransfer_1 Sulfotransfer_3
Other DBs
NCBI-GeneID: 3340
NCBI-ProteinID: NP_001534
OMIM: 600853
HGNC: 7680
Ensembl: ENSG00000070614
UniProt: P52848 A8K8T3
Structure
LinkDB
Position
5:150497779..150558211
AA seq 882 aa
MPALACLRRLCRHVSPQAVLFLLFIFCLFSVFISAYYLYGWKRGLEPSADAPEPDCGDPP
PVAPSRLLPLKPVQAATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKG
DMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSA
QLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLL
AKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAF
LTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSG
KFFHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHG
IPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMV
LPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGL
YTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKT
CDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYME
FFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAH
DDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKL
LRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEM
DLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDLQNTR
NT seq 2649 nt   +upstreamnt  +downstreamnt
atgcctgccctggcatgcctccggaggctgtgtcggcacgtgtccccgcaggctgtcctt
ttcctgctgttcatcttctgcctgttcagcgttttcatctcggcctactacctatatggc
tggaagcgaggcctggagccctcggcggatgcccccgagcctgactgcggggacccgccg
cctgtggcccccagtcgcctgctgccactcaagcctgtgcaggcagccaccccttcccgc
acagacccgttggtgctggtctttgtggagagcctctactcgcaactgggccaggaggtg
gtggccatcctggagtccagccgcttcaaataccgcacagagattgcgccgggcaagggt
gacatgcccacgctcactgacaagggccgtggccgcttcgccctcatcatctatgagaac
atcctcaagtatgtcaacctggacgcctggaaccgggagctgctggacaagtactgtgtg
gcctacggcgtgggcatcattggcttcttcaaggccaatgagaacagcctgctgagtgcg
cagctcaagggcttccccctgttcctgcactcaaacctgggcctgaaggactgcagcatc
aaccccaagtccccgctgctctacgtgacgcgacctagcgaggtggagaaaggtgtgctc
cccggcgaggactggacggttttccagtcaaatcactccacctatgagccagtgctgctg
gccaagacgcgctcgtctgagtccatcccacacctgggcgcagacgccggcctgcatgct
gcactgcacgccactgtggtccaggacctgggcctgcacgacggcatccagcgcgtgctg
tttggcaacaacctgaacttctggctgcacaagcttgtcttcgtggatgccgtggccttc
ctcacggggaagcgcctctccctgccattggaccgctacatcctggtggacattgatgac
atcttcgtgggcaaggagggcacacgcatgaaggtggaggacgtgaaggccctgtttgac
acacagaacgaactacgcgcacacatcccaaacttcaccttcaacctgggctactcaggg
aaattcttccacacaggtaccaatgctgaggacgctggggatgatctgctgctgtcgtat
gtgaaggagttctggtggttcccccacatgtggagccacatgcagccccaccttttccac
aaccagtccgtgttggccgagcagatggccttgaacaagaagttcgctgtcgagcatggc
attcccacagacatggggtatgcagtggcgccccaccactcgggcgtgtaccccgtgcac
gtgcagctgtacgaggcttggaagcaggtgtggagcatccgcgtgaccagcacggaggag
tacccccacctgaagccagcccgctaccgccgtggcttcatccacaatggcatcatggtt
ctcccacggcagacctgcggcctcttcacacacaccatcttctacaacgagtaccctggc
ggctccagtgagctggacaagatcatcaacgggggcgagctcttcctcaccgtgctcctc
aatcctatcagcatcttcatgacgcacctgtccaactatgggaatgaccgcctgggcctg
tacaccttcaagcacctggtgcgcttcctgcactcctggacgaacctccggctgcagaca
ctgccccctgtgcagttggcgcagaagtacttccagatcttctccgaggagaaggacccg
ctctggcaggacccctgcgaggacaaacgtcacaaagacatctggtccaaggagaagacg
tgtgaccgcttcccaaagctcctcatcatcggcccccagaaaacaggcaccactgccctc
tacctgttcctgggcatgcaccctgacctaagcagcaactaccccagctctgagaccttt
gaggagatccagttttttaatggccacaactatcacaaaggcatcgactggtacatggag
ttcttccccatcccttccaacaccacctccgacttctactttgagaaaagcgccaactac
tttgattcagaagtggcgccccggcgggcagcagccctcttgcccaaagccaaggtcctg
accatcctcatcaaccccgcggaccgggcctattcctggtaccagcaccagcgagcccat
gacgacccagtggccctaaagtacaccttccatgaggtgattaccgccggctctgacgca
tcctcgaagctgcgtgccctccagaaccgctgcctggtccctggctggtacgccacccac
atcgagcgctggctcagtgcctatcacgccaaccagattctggtcttggatggcaaactg
cttcgcacagaacctgccaaagtgatggacatggtgcagaagttccttggggtgaccaac
accattgactaccacaaaaccttggcgtttgatccaaagaaaggattttggtgccaactg
cttgaaggaggaaaaaccaagtgtctgggcaaaagcaagggccggaaatatcccgagatg
gacttggattcccgagccttcctgaaggactattaccgggaccacaacatcgagctctcc
aagctgctgtataagatgggccagacacttcccacttggctacgagaggacctccagaac
accaggtag

DBGET integrated database retrieval system