Homo sapiens (human): 3419
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Entry
3419 CDS
T01001
Symbol
IDH3A, RP90
Name
(RefSeq) isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
KO
K00030
isocitrate dehydrogenase (NAD+) [EC:
1.1.1.41
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00020
Citrate cycle (TCA cycle)
hsa01100
Metabolic pathways
hsa01200
Carbon metabolism
hsa01210
2-Oxocarboxylic acid metabolism
hsa01230
Biosynthesis of amino acids
Module
hsa_M00009
Citrate cycle (TCA cycle, Krebs cycle)
hsa_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Network
nt06031
Citrate cycle and pyruvate metabolism
Element
N01604
Citrate cycle, first carbon oxidation
Disease
H00527
Retinitis pigmentosa
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
3419 (IDH3A)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.41 isocitrate dehydrogenase (NAD+)
3419 (IDH3A)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
3419
NCBI-ProteinID:
NP_005521
OMIM:
601149
HGNC:
5384
Ensembl:
ENSG00000166411
UniProt:
P50213
Structure
PDB
PDBj
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All DBs
Position
15:78149362..78171945
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AA seq
366 aa
AA seq
DB search
MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAP
IQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDL
YANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIA
EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMV
QDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKD
MANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICR
RVKDLD
NT seq
1101 nt
NT seq
+upstream
nt +downstream
nt
atggctgggcccgcgtggatctctaaggtctctcggctgctgggggcattccacaaccca
aaacaggtgaccagaggttttactggtggtgttcagacagtaactttaattccaggagat
ggtattggcccagaaatttcagctgcagttatgaagatttttgatgctgccaaagcacct
attcagtgggaggagcggaacgtcactgccattcaaggacctggaggaaagtggatgatc
ccttcagaggctaaagagtccatggataagaacaagatgggcttgaaaggccctttgaag
accccaatagcagccggtcacccatctatgaatttactgctgcgcaaaacatttgacctt
tacgcgaatgtccgaccatgtgtctctatcgaaggctataaaaccccttacaccgatgta
aatattgtgaccattcgagagaacacagaaggagaatacagtggaattgagcatgtgatt
gttgatggagtcgtgcagagtatcaagctcatcaccgagggggcgagcaagcgcattgct
gagtttgcctttgagtatgcccggaacaaccaccggagcaacgtcacggcggtgcacaaa
gccaacatcatgcggatgtcagatgggctttttctacaaaaatgcagggaagttgcagaa
agctgtaaagatattaaatttaatgagatgtaccttgatacagtatgtttgaatatggta
caagatccttcccaatttgatgttcttgttatgccaaatttgtatggagacatccttagt
gacttgtgtgcaggattgatcggaggtctcggtgtgacaccaagtggcaacattggagcc
aatggggttgcaatttttgagtcggttcatgggacggctccagacattgcaggcaaggac
atggcgaatcccacagccctcctgctcagtgccgtgatgatgctgcgccacatgggactt
tttgaccatgctgcaagaattgaggctgcgtgttttgctacaattaaggacggaaagagc
ttgacaaaagatttgggaggcaatgcaaaatgctcagacttcacagaggaaatctgtcgc
cgagtaaaagatttagattaa
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