Homo sapiens (human): 3486
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Entry
3486 CDS
T01001
Symbol
IGFBP3, BP-53, IBP-3, IBP3, IGFBP-3
Name
(RefSeq) insulin like growth factor binding protein 3
KO
K10138
insulin-like growth factor-binding protein 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04115
p53 signaling pathway
hsa04218
Cellular senescence
hsa04935
Growth hormone synthesis, secretion and action
hsa05202
Transcriptional misregulation in cancer
Network
nt06240
Transcription (cancer)
Element
N00134
EWSR1-FLI1 fusion to transcriptional repression
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
3486 (IGFBP3)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
3486 (IGFBP3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
3486 (IGFBP3)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
3486 (IGFBP3)
Membrane trafficking [BR:
hsa04131
]
Endocytosis
Others
Insulin-like growth factor-binding proteins
3486 (IGFBP3)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of other cancer cells
3486 (IGFBP3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Thyroglobulin_1
IGFBP
Motif
Other DBs
NCBI-GeneID:
3486
NCBI-ProteinID:
NP_000589
OMIM:
146732
HGNC:
5472
Ensembl:
ENSG00000146674
UniProt:
P17936
B3KPF0
Structure
PDB
PDBj
LinkDB
All DBs
Position
7:complement(45912245..45921272)
Genome browser
AA seq
291 aa
AA seq
DB search
MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE
LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
SRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHA
KDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNC
DKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
NT seq
876 nt
NT seq
+upstream
nt +downstream
nt
atgcagcgggcgcgacccacgctctgggccgctgcgctgactctgctggtgctgctccgc
gggccgccggtggcgcgggctggcgcgagctcggcgggcttgggtcccgtggtgcgctgc
gagccgtgcgacgcgcgtgcactggcccagtgcgcgcctccgcccgccgtgtgcgcggag
ctggtgcgcgagccgggctgcggctgctgcctgacgtgcgcactgagcgagggccagccg
tgcggcatctacaccgagcgctgtggctccggccttcgctgccagccgtcgcccgacgag
gcgcgaccgctgcaggcgctgctggacggccgcgggctctgcgtcaacgctagtgccgtc
agccgcctgcgcgcctacctgctgccagcgccgccagctccaggaaatgctagtgagtcg
gaggaagaccgcagcgccggcagtgtggagagcccgtccgtctccagcacgcaccgggtg
tctgatcccaagttccaccccctccattcaaagataatcatcatcaagaaagggcatgct
aaagacagccagcgctacaaagttgactacgagtctcagagcacagatacccagaacttc
tcctccgagtccaagcgggagacagaatatggtccctgccgtagagaaatggaagacaca
ctgaatcacctgaagttcctcaatgtgctgagtcccaggggtgtacacattcccaactgt
gacaagaagggattttataagaaaaagcagtgtcgcccttccaaaggcaggaagcggggc
ttctgctggtgtgtggataagtatgggcagcctctcccaggctacaccaccaaggggaag
gaggacgtgcactgctacagcatgcagagcaagtag
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