Homo sapiens (human): 3588
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Entry
3588 CDS
T01001
Symbol
IL10RB, CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IBD25, IL-10R2, IL-10RB
Name
(RefSeq) interleukin 10 receptor subunit beta
KO
K05135
interleukin 10 receptor beta
Organism
hsa
Homo sapiens (human)
Pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04061
Viral protein interaction with cytokine and cytokine receptor
hsa04630
JAK-STAT signaling pathway
hsa05145
Toxoplasmosis
hsa05152
Tuberculosis
hsa05163
Human cytomegalovirus infection
Network
nt06167
Human cytomegalovirus (HCMV)
nt06518
JAK-STAT signaling
Element
N00415
IL10 family to Jak-STAT signaling pathway
N00416
HCMV vIL10 to IL10-JAK-STAT signaling pathway
Disease
H00286
Crohn disease
H00412
Hepatitis B
H01227
Inflammatory bowel disease (IBD)
Drug target
Ilodecakin:
D04505
Pegilodecakin:
D11200
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
3588 (IL10RB)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
3588 (IL10RB)
04061 Viral protein interaction with cytokine and cytokine receptor
3588 (IL10RB)
09160 Human Diseases
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
3588 (IL10RB)
09171 Infectious disease: bacterial
05152 Tuberculosis
3588 (IL10RB)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
3588 (IL10RB)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04050 Cytokine receptors [BR:
hsa04050
]
3588 (IL10RB)
04090 CD molecules [BR:
hsa04090
]
3588 (IL10RB)
Cytokine receptors [BR:
hsa04050
]
Interleukin receptor families
IL10/28 receptor family
3588 (IL10RB)
CD molecules [BR:
hsa04090
]
Proteins
3588 (IL10RB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Interfer-bind
Tissue_fac
fn3
XK-related
MP_p6
Motif
Other DBs
NCBI-GeneID:
3588
NCBI-ProteinID:
NP_000619
OMIM:
123889
HGNC:
5965
Ensembl:
ENSG00000243646
UniProt:
Q08334
Structure
PDB
LinkDB
All DBs
Position
21:33266367..33310182
Genome browser
AA seq
325 aa
AA seq
DB search
MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYR
IFQDKCMNTTLTECDFSSLSKYGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQV
EVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRN
LEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLG
CFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAE
DSESGKQNPGDSCSLGTPPGQGPQS
NT seq
978 nt
NT seq
+upstream
nt +downstream
nt
atggcgtggagccttgggagctggctgggtggctgcctgctggtgtcagcattgggaatg
gtaccacctcccgaaaatgtcagaatgaattctgttaatttcaagaacattctacagtgg
gagtcacctgcttttgccaaagggaacctgactttcacagctcagtacctaagttatagg
atattccaagataaatgcatgaatactaccttgacggaatgtgatttctcaagtctttcc
aagtatggtgaccacaccttgagagtcagggctgaatttgcagatgagcattcagactgg
gtaaacatcaccttctgtcctgtggatgacaccattattggaccccctggaatgcaagta
gaagtacttgctgattctttacatatgcgtttcttagcccctaaaattgagaatgaatac
gaaacttggactatgaagaatgtgtataactcatggacttataatgtgcaatactggaaa
aacggtactgatgaaaagtttcaaattactccccagtatgactttgaggtcctcagaaac
ctggagccatggacaacttattgtgttcaagttcgagggtttcttcctgatcggaacaaa
gctggggaatggagtgagcctgtctgtgagcaaacaacccatgacgaaacggtcccctcc
tggatggtggccgtcatcctcatggcctcggtcttcatggtctgcctggcactcctcggc
tgcttcgccttgctgtggtgcgtttacaagaagacaaagtacgccttctcccctaggaat
tctcttccacagcacctgaaagagtttttgggccatcctcatcataacacacttctgttt
ttctcctttccattgtcggatgagaatgatgtttttgacaagctaagtgtcattgcagaa
gactctgagagcggcaagcagaatcctggtgacagctgcagcctcgggaccccgcctggg
caggggccccaaagctag
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