Homo sapiens (human): 374875
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Entry
374875 CDS
T01001
Symbol
HSD11B1L, 11-DH3, 11-beta-HSD3, HSD1L, HSD3, SCDR10, SCDR10B, SDR26C2
Name
(RefSeq) hydroxysteroid 11-beta dehydrogenase 1 like
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00140
Steroid hormone biosynthesis
hsa00980
Metabolism of xenobiotics by cytochrome P450
hsa01100
Metabolic pathways
hsa05204
Chemical carcinogenesis - DNA adducts
Module
hsa_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
374875 (HSD11B1L)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
374875 (HSD11B1L)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
374875 (HSD11B1L)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
374875 (HSD11B1L)
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Gene cluster
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Motif
Other DBs
NCBI-GeneID:
374875
NCBI-ProteinID:
NP_940935
HGNC:
30419
Ensembl:
ENSG00000167733
UniProt:
Q7Z5J1
LinkDB
All DBs
Position
19:5681027..5688522
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AA seq
315 aa
AA seq
DB search
MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA
HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP
AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA
AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQ
SQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVR
RLCRGLARPHLFGHD
NT seq
948 nt
NT seq
+upstream
nt +downstream
nt
atgaaggtgcttctcctcacagggctgggggccctgttcttcgcctattattgggatgac
aacttcgacccagccagcctccagggagcgcgagtgctgctgacaggggccaacgctggt
gttggtgaggagctggcctatcactacgcgcgtctgggctcccacctggtgctcactgcc
cacactgaggctctcctgcagaaggtggtagggaactgccggaagctgggcgcccccaag
gtcttctacatcgcggcggacatggcctcccctgaggcgcccgagagcgtggtgcagttt
gcgctggacaagctgggcgggctggactacctcgtgctgaaccacatcggcggcgccccg
gccggcacgcgagcccgcagcccccaggcaactcgctggctcatgcaggtaaactttgtg
agctacgtgcaactgacgtcgcgggcgctgcccagcctgacggacagcaagggctccctg
gtggtggtgtcctcgctgctcggccgcgtgcccacgtcgttctccactccctactcggcg
gccaagtttgcgctggacggcttcttcggctccctgcggcgggagctggacgtgcaggac
gtgaacgtggccatcaccatgtgcgtcctgggcctccgagatcgcgcctccgccgccgag
gcagtcaggagctcaacgtcacggccgcggcagcctgagcaccggggggtgcccctccag
tcccagacggcaatgttcctccctccaactgtccctggagccagaacactcacagagaca
cccctgagagggtggccacagcccaagatgaagtcatcaagacagaaaagcaaaaccgag
aaaaacgacgggcacctggaaccagtcacggcttgggaggtgcaggtgccccgtgttagg
cgcctttgtcggggacttgcaaggcctcacctgtttggccatgattga
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