Homo sapiens (human): 3760
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Entry
3760 CDS
T01001
Symbol
KCNJ3, GIRK1, KGA, KIR3.1
Name
(RefSeq) potassium inwardly rectifying channel subfamily J member 3
KO
K04997
potassium inwardly-rectifying channel subfamily J member 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04713
Circadian entrainment
hsa04723
Retrograde endocannabinoid signaling
hsa04724
Glutamatergic synapse
hsa04725
Cholinergic synapse
hsa04726
Serotonergic synapse
hsa04728
Dopaminergic synapse
hsa04915
Estrogen signaling pathway
hsa04921
Oxytocin signaling pathway
hsa04929
GnRH secretion
hsa05032
Morphine addiction
Network
nt06544
Neuroactive ligand signaling
Element
N01889
Gbeta/gamma-KCNJ signaling
Drug target
Amiodarone (
DG00204
):
D00636
<JP/US>
D02910
Bepridil (
DG00333
):
D00631
<JP>
D07520
Dronedarone (
DG00207
):
D02537
D03914
<US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04929 GnRH secretion
3760 (KCNJ3)
04915 Estrogen signaling pathway
3760 (KCNJ3)
04921 Oxytocin signaling pathway
3760 (KCNJ3)
09156 Nervous system
04724 Glutamatergic synapse
3760 (KCNJ3)
04725 Cholinergic synapse
3760 (KCNJ3)
04728 Dopaminergic synapse
3760 (KCNJ3)
04726 Serotonergic synapse
3760 (KCNJ3)
04723 Retrograde endocannabinoid signaling
3760 (KCNJ3)
09159 Environmental adaptation
04713 Circadian entrainment
3760 (KCNJ3)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
3760 (KCNJ3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
3760 (KCNJ3)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Potassium channel, inwardly-rectifying (Kir)
3760 (KCNJ3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
IRK_C
IRK
Motif
Other DBs
NCBI-GeneID:
3760
NCBI-ProteinID:
NP_002230
OMIM:
601534
HGNC:
6264
Ensembl:
ENSG00000162989
UniProt:
P48549
LinkDB
All DBs
Position
2:154698695..154858354
Genome browser
AA seq
501 aa
AA seq
DB search
MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNL
GSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNY
TPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCM
FIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPE
GEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILE
GIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKE
QEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDITTKLPSKLQKITGREDFPKKLLRMS
STTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGG
AARMEGNLPAKLRKMNSDRFT
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atgtctgcactccgaaggaaatttggggacgattatcaggtagtgaccacatcgtccagc
ggctcgggcttgcagccccaggggccaggccaggaccctcagcagcagcttgtgcccaag
aagaagcggcagcggttcgtggacaagaacggccggtgcaatgtacagcacggcaacctg
ggcagcgagacaagccgctacctctcggacctcttcaccacgctggtggacctcaagtgg
cgctggaacctcttcatcttcattctcacctacaccgtggcctggcttttcatggcgtcc
atgtggtgggtgatcgcctacactcggggcgacctgaacaaagcccacgtcggtaactac
acgccttgcgtggccaatgtctataacttcccttctgccttcctcttcttcatcgagacg
gaggccaccatcggctatggctaccgatacatcacagacaagtgccccgagggcatcatc
ctcttcctcttccagtccatcctgggctccatcgtggacgccttcctcatcggctgcatg
ttcatcaagatgtcccagcccaagaagcgcgccgagaccctcatgttcagcgagcacgcg
gtgatctccatgagggacggaaaactcacgcttatgttccgggtgggcaacctgcgcaac
agccacatggtctccgcgcagattcgctgcaagctgctcaaatctcggcagacacctgag
ggtgagttccttccccttgaccaacttgaactggatgtaggttttagtacaggggcagat
caactttttcttgtgtcccccctcacaatttgccacgtgatcgatgccaaaagccccttt
tatgacctatcccagcgaagcatgcaaactgaacagttcgagattgtcgtcatcctagaa
ggcattgtggaaacaactgggatgacttgtcaagctcgaacatcatatactgaagatgaa
gttctttggggtcatcgtttttttcctgtaatttccttagaagagggattctttaaagtt
gattactcccagttccatgcaacatttgaagtccccaccccaccttacagtgtgaaagag
caggaggaaatgcttctcatgtcgtcccctttaatagcaccagccataactaacagcaaa
gaaagacataattctgtggaatgcttagatggactagatgatattactacaaaactacca
tctaagctgcagaaaattactggaagagaagactttcccaaaaaactcttgaggatgagt
tctacaacttcagaaaaagcctacagcttgggagacttgcccatgaaacttcaacgaata
agttcagttccgggcaactcagaagaaaaactggtatctaaaaccaccaagatgttatct
gatcccatgagccagtctgtggctgatttgccaccaaagcttcaaaagatggctggagga
gcagctaggatggaagggaaccttccagccaaattaagaaaaatgaactctgatcgcttc
acataa
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