KEGG T01001: 382

Homo sapiens (human): 382

Entry

382               CDS       T01001

Symbol

ARF6

Name

(RefSeq) ARF GTPase 6

K07941

ADP-ribosylation factor 6

Organism

hsa Homo sapiens (human)

Pathway

hsa04014

Ras signaling pathway

hsa04072

Phospholipase D signaling pathway

hsa04144

Endocytosis

hsa04666

Fc gamma R-mediated phagocytosis

hsa05130

Pathogenic Escherichia coli infection

hsa05131

Shigellosis

hsa05132

Salmonella infection

hsa05135

Yersinia infection

Network

nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella

Element

N01066

ARNO-ARF-ACTB_G signaling pathway

N01067

Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway

N01084

Escherichia EspG to ARNO-ARF-ACTB/G signaling pathway

N01129

Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    382 (ARF6)
   04072 Phospholipase D signaling pathway
    382 (ARF6)
09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    382 (ARF6)
09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    382 (ARF6)
09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    382 (ARF6)
   05131 Shigellosis
    382 (ARF6)
   05135 Yersinia infection
    382 (ARF6)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    382 (ARF6)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    382 (ARF6)
   04031 GTP-binding proteins [BR:hsa04031]
    382 (ARF6)
Membrane trafficking [BR:hsa04131]
Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    382 (ARF6)
  Arf GTPases and associated proteins
   Arf GTPases
    382 (ARF6)
Exosome [BR:hsa04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   382 (ARF6)
  Exosomal proteins of colorectal cancer cells
   382 (ARF6)
GTP-binding proteins [BR:hsa04031]
Small (monomeric) G-proteins
  Arf/Sar Family
   Arf [OT]
    382 (ARF6)

SSDB

Motif

Pfam:

Arf Roc G-alpha Ras SRPRB Gtr1_RagA MMR_HSR1 GTP_EFTU 6PF2K SpoOE-like CRISPR_Cas2

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

14:49893082..49897054

AA seq 175 aa
MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFN
VWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIF
ANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS

NT seq 528 nt +upstreamnt +downstreamnt
atggggaaggtgctatccaaaatcttcgggaacaaggaaatgcggatcctcatgttgggc
ctggacgcggccggcaagacaacaatcctgtacaagttgaagctgggccagtcggtgacc
accattcccactgtgggtttcaacgtggagacggtgacttacaaaaatgtcaagttcaac
gtatgggatgtgggcggccaggacaagatccggccgctctggcggcattactacactggg
acccaaggtctcatcttcgtagtggactgcgccgaccgcgaccgcatcgatgaggctcgc
caggagctgcaccgcattatcaatgaccgggagatgagggacgccataatcctcatcttc
gccaacaagcaggacctgcccgatgccatgaaaccccacgagatccaggagaaactgggc
ctgacccggattcgggacaggaactggtatgtgcagccctcctgtgccacctcaggggac
ggactctatgaggggctcacatggttaacctctaactacaaatcttaa

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