Homo sapiens (human): 399694 Help Entry 399694            CDS       T01001                                  Symbol SHC4, RaLP, SHCD Name (RefSeq) SHC adaptor protein 4   KO K17449   SHC-transforming protein 4 Organism hsa  Homo sapiens (human) Pathway hsa01521   EGFR tyrosine kinase inhibitor resistance hsa01522   Endocrine resistance hsa04012   ErbB signaling pathway hsa04014   Ras signaling pathway hsa04062   Chemokine signaling pathway hsa04072   Phospholipase D signaling pathway hsa04510   Focal adhesion hsa04650   Natural killer cell mediated cytotoxicity hsa04722   Neurotrophin signaling pathway hsa04910   Insulin signaling pathway hsa04915   Estrogen signaling pathway hsa04917   Prolactin signaling pathway hsa04926   Relaxin signaling pathway hsa04935   Growth hormone synthesis, secretion and action hsa05034   Alcoholism hsa05100   Bacterial invasion of epithelial cells hsa05206   MicroRNAs in cancer hsa05214   Glioma hsa05220   Chronic myeloid leukemia hsa05224   Breast cancer hsa05225   Hepatocellular carcinoma hsa05226   Gastric cancer Network nt06526  MAPK signaling   Element N01595   Regulation of GF-RTK-RAS-ERK signaling pathway, adaptor proteins Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     399694 (SHC4)    04072 Phospholipase D signaling pathway     399694 (SHC4)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     399694 (SHC4)    04062 Chemokine signaling pathway     399694 (SHC4)   09152 Endocrine system    04915 Estrogen signaling pathway     399694 (SHC4)    04917 Prolactin signaling pathway     399694 (SHC4)    04926 Relaxin signaling pathway     399694 (SHC4)    04935 Growth hormone synthesis, secretion and action     399694 (SHC4)   09156 Nervous system    04722 Neurotrophin signaling pathway     399694 (SHC4)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     399694 (SHC4)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     399694 (SHC4)    05226 Gastric cancer     399694 (SHC4)    05214 Glioma     399694 (SHC4)    05220 Chronic myeloid leukemia     399694 (SHC4)    05224 Breast cancer     399694 (SHC4)   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     399694 (SHC4)   09165 Substance dependence    05034 Alcoholism     399694 (SHC4)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     399694 (SHC4)    01522 Endocrine resistance     399694 (SHC4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PID SH2 Delta_lysin DUF7063 Motif Other DBs NCBI-GeneID:  399694 NCBI-ProteinID:  NP_976224 OMIM:  617372 HGNC:  16743 Ensembl:  ENSG00000185634 UniProt:  Q6S5L8 LinkDB All DBs Position 15:complement(48823741..48963919) Genome browser AA seq 630 aa AA seqDB search MRERGQDSLAGLVLYVGLFGHPGMLHRAKYSRFRNESITSLDEGSSGGSVGNKGSPQPPH PALAPHLPTEDATLPSQESPTPLCTLIPRMASMKLANPATLLSLKNFCLGTKEVPRLKLQ ESRDPGSSGPSSPETSLSRSGTAPPPQQDLVGHRATALTPDSCPLPGPGEPTLRSRQDRH FLQHLLGMGMNYCVRYMGCVEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKKRK PPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDT TDYVAYVAKDPVNQRACHILECHNGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEV HIDSHAEEREDHEYYNEIPGKQPPVGGVSDMRIKVQATEQMAYCPIQCEKLCYLPGNSKC SSVYENCLEQSRAIGNVHPRGVQSQRDTSLLKHTCRVDLFDDPCYINTQALQSTPGSAGN QRSAQPLGSPWHCGKAPETVQPGATAQPASSHSLPHIKQQLWSEECYHGKLSRKAAESLL VKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHMDN SLPIISSGSEVSLKQPVRKDNNPALLHSNK NT seq 1893 nt NT seq  +upstreamnt  +downstreamnt atgcgagaacgcggccaggacagcctggcaggactcgtgctgtatgtaggactcttcggg caccccgggatgctgcacagggccaagtacagccgctttcggaacgagtcgatcacgtcc ttggacgaaggtagctccggaggctcggtcgggaacaagggctcgccgcagcctccccac cccgccctggcacctcacctgccgactgaagatgccaccttgccgtcgcaggagagcccc accccactgtgcaccttgatcccccgcatggcaagcatgaagctggccaacccggccact ttgctgagtctgaaaaacttttgcctgggtaccaaagaggtgcctcggctgaagctccag gaaagccgggacccaggttccagcggcccctcttccccagaaaccagtttaagtaggtcc gggactgcacctccaccgcagcaggacctggtgggacacagggcaaccgccctaacccct gattcgtgcccgcttcctggccctggggagccaacacttaggagcaggcaggacaggcac tttctacagcacctgttggggatgggcatgaactactgtgtgaggtacatgggctgtgtt gaagtgctgcaatcaatgagatcactggattttggaatgagaacccaagttacaagggaa gcaataagtcgcctgtgtgaagctgtccccggggcaaatggagccattaaaaagcgaaag cctccagttaagttcctatcaacagtccttggcaaaagtaatcttcagttttcaggaatg aatataaaactgaccatctcaacatgcagtctcacattgatgaatcttgacaaccaacag attattgcaaatcatcatatgcagtctatttcatttgcctctggaggggatcctgatact acagactatgttgcctacgtagctaaagatccagttaatcaacgagcctgtcacatattg gaatgccacaatggaatggcccaagacgtcataagtaccatagggcaggcttttgaactc cggtttaaacagtacttgaaaaatccttctttgaatacttcttgtgaaagtgaggaggtg catattgatagccatgccgaggagagagaagatcatgaatattacaatgaaattccaggg aagcagccaccagtaggtggtgtttcagatatgcggatcaaagttcaagccacggaacaa atggcttactgccccatacagtgtgaaaagttgtgctatttgcctggaaactccaagtgc agcagtgtatatgagaactgtttagaacaaagcagggcaataggtaatgtccatccaaga ggggtgcagtcccagcgagatacctcattattgaagcacacgtgccgagtggatctcttt gatgacccctgctacattaatacacaggctcttcaaagtacacctggctctgctggaaat caaaggtcagcccaaccactggggagcccatggcactgcggaaaggcaccagaaactgtt cagccgggtgccacagcccagcctgccagctcacattctttgccacacattaagcagcag ctgtggagcgaagaatgctatcatggcaagctgagcaggaaggcggcagagagcctcttg gtaaaggatggggactttttggttcgagagagtgcaacatcccctggccaatatgtgctg agtggactacagggaggccaagcaaaacatcttctcctggtggatcctgaaggcaaggtg aggaccaaggatcatgtatttgataatgtcggccaccttatcagataccatatggataac agtttgccaatcatctcctctggaagcgaagtaagccttaaacaaccagtgagaaaagat aataatccagcacttttgcattccaacaaatga

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