Homo sapiens (human): 4012
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Entry
4012 CDS
T01001
Symbol
LNPEP, CAP, IRAP, P-LAP, PLAP
Name
(RefSeq) leucyl and cystinyl aminopeptidase
KO
K01257
cystinyl aminopeptidase [EC:
3.4.11.3
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04614
Renin-angiotensin system
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04614 Renin-angiotensin system
4012 (LNPEP)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
4012 (LNPEP)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.11 Aminopeptidases
3.4.11.3 cystinyl aminopeptidase
4012 (LNPEP)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M1
4012 (LNPEP)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M1
ERAP1_C
Peptidase_M1_N
pP_pnuc_1
Dynactin
Motif
Other DBs
NCBI-GeneID:
4012
NCBI-ProteinID:
NP_005566
OMIM:
151300
HGNC:
6656
Ensembl:
ENSG00000113441
UniProt:
Q9UIQ6
Structure
PDB
PDBj
LinkDB
All DBs
Position
5:96936080..97037513
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AA seq
1025 aa
AA seq
DB search
MEPFTNDRLQLPRNMIENSMFEEEPDVVDLAKEPCLHPLEPDEVEYEPRGSRLLVRGLGE
HEMEEDEEDYESSAKLLGMSFMNRSSGLRNSATGYRQSPDGACSVPSARTMVVCAFVIVV
AVSVIMVIYLLPRCTFTKEGCHKKNQSIGLIQPFATNGKLFPWAQIRLPTAVVPLRYELS
LHPNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTFMSAVSSQEKQAEILEYAYH
GQIAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESNEKKYFAATQFEPLAAR
SAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQDEFSESVKMSTYLVA
FIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLEFFQNYFEIQYPLKKLDLV
AIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAHELAHQWFGNLVTMKWW
NDLWLNEGFATFMEYFSLEKIFKELSSYEDFLDARFKTMKKDSLNSSHPISSSVQSSEQI
EEMFDSLSYFKGSSLLLMLKTYLSEDVFQHAVVLYLHNHSYASIQSDDLWDSFNEVTNQT
LDVKRMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNMKPEIQPSDTSYLWHIPLSYVT
EGRNYSKYQSVSLLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINP
YVLSDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTDLIYNLLE
KLGYMDLASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRSALLEFACTHNLGNCSTTAM
KLFDDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLGKYISIGSEAEKNKILEALASS
EDVRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGS
YTIQNIVAGSTYLFSTKTHLSEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKNLKS
LTWWL
NT seq
3078 nt
NT seq
+upstream
nt +downstream
nt
atggagcccttcaccaatgatcggcttcagctccccaggaatatgattgaaaacagcatg
tttgaggaagaaccagatgtggtggatttagccaaagagccttgtttacatcctctagag
cctgatgaggtggaatatgagccccggggttcccgactgctggtgcggggtcttggtgag
catgagatggaggaggatgaagaggattatgagtcatcagcaaagctgctgggcatgtcc
ttcatgaatagaagctcaggccttcggaacagtgcaactggttacaggcagagcccagat
ggggcttgttcagtaccctctgcaaggaccatggtggtctgtgcttttgtcatcgtggtt
gctgtttctgtaatcatggtgatttacttactgcccagatgtacctttaccaaagaaggc
tgccataaaaaaaaccagtcaattggactaattcagccatttgcaacaaatgggaaattg
tttccatgggcacagatcaggcttcccactgccgttgtgccactacgctatgaactcagc
ctacacccgaacctaacctcgatgacattcaggggttctgtgacaatttcagttcaggct
cttcaggtcacatggaatatcattcttcatagcacaggtcataatatttcaagagtgacc
tttatgtcagcagtttcaagccaagaaaaacaagctgagatcctggaatatgcatatcat
ggacagatcgccattgttgcccccgaagcccttctagcagggcacaattatacgttgaag
atagagtactcggcaaatatatctagttcttattatgggttttatggcttctcctacaca
gatgaaagtaatgagaaaaagtactttgcagcaactcagtttgaacccctggcagcaaga
tctgcttttccttgttttgatgaaccagcatttaaagccacttttatcatcaagatcata
agggatgagcaatacaccgctttatcaaatatgcctaagaagtcatcagtcgttctagat
gatggacttgttcaggatgagttttctgagagtgtgaagatgagcacttacttggttgct
ttcattgtgggagagatgaagaacctgagtcaggacgtaaatggaaccctggtttctata
tatgctgtaccagaaaagattggtcaagttcattatgccttggaaacaactgtgaagctt
cttgagttttttcaaaactactttgaaattcagtacccacttaagaaattggatttggtg
gctattcctgactttgaagcaggagcaatggaaaattggggtttgctcaccttccgagag
gagacacttctgtatgacagtaacacttcttcaatggcggatagaaagctggtgactaaa
atcattgctcatgagctggcccaccagtggtttggcaatctggtaacaatgaagtggtgg
aatgacctatggctaaatgaaggttttgccactttcatggagtatttctctttggaaaaa
atattcaaagagctttctagttatgaagatttcttagatgctcgatttaaaaccatgaag
aaagattccttaaattcatctcatccaatatcatcatctgttcagtcttcagaacaaatt
gaagaaatgtttgattctctttcctattttaagggatcttctctcttgttgatgttgaaa
acttaccttagtgaagatgtgtttcaacatgctgttgtcctttacctgcataatcacagc
tatgcatctattcaaagtgatgatctgtgggatagttttaatgaggtcacaaaccaaaca
ctagatgtaaagagaatgatgaaaacctggaccctgcagaaaggatttcctttagtgact
gttcaaaagaaaggaaaggaactttttatacaacaagagagattctttttaaatatgaag
cctgaaattcagccttcagatacaagctacctgtggcatattccactatcctatgtcact
gaaggaagaaattattcaaaatatcaatcggtatcattactggataagaaatcaggtgtc
atcaatcttacagaagaagtgctgtgggtcaaagtgaatataaacatgaatggttattat
attgtacactatgcagatgatgattgggaagcactaatccatcagttgaaaataaatcct
tatgttctgagtgacaaagaccgagccaaccttatcaacaacatctttgaacttgcaggc
ctaggcaaggtacctctcaagagggcctttgatttgattaattatcttggaaatgagaac
catactgcacccatcaccgaagccctgtttcagacagacctcatctataacctccttgaa
aaactgggatacatggatctggcctcaagactggtgactagggtatttaaattacttcaa
aaccaaattcaacaacaaacttggactgatgagggcactccatctatgcgagagcttcgg
tcagccctgctagagtttgcttgcacccacaacctggggaactgctctactactgccatg
aaactgtttgatgactggatggcatccaatggaactcaaagcctacctactgatgtcatg
acaactgtgttcaaagttggagcaaaaactgacaaaggctggtcattccttttgggcaaa
tacatttctataggctctgaagcagagaagaacaaaatactagaagcacttgccagctca
gaggatgtgcggaagctttactggttaatgaaaagtagcctgaatggagataacttccga
acacagaagctgtcttttatcattagaacagtgggtcgacattttcctggacacttactg
gcatgggattttgtcaaagagaactggaataagcttgtacagaagttccctctggggtcc
tataccatacaaaatattgttgctggatcaacttacctgttttcaacaaagacacattta
tctgaggttcaggcattctttgaaaatcagtcagaggcaaccttccggcttcgttgtgtc
caggaggctttggaagtcattcagttgaatatccagtggatggagaagaacctcaaaagt
ctcacatggtggctgtag
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