Homo sapiens (human): 438
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Entry
438 CDS
T01001
Symbol
ASMT, ASMTY, HIOMT, HIOMTY
Name
(RefSeq) acetylserotonin O-methyltransferase
KO
K00543
acetylserotonin O-methyltransferase [EC:
2.1.1.4
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00380
Tryptophan metabolism
hsa01100
Metabolic pathways
Module
hsa_M00037
Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00380 Tryptophan metabolism
438 (ASMT)
Enzymes [BR:
hsa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.4 acetylserotonin O-methyltransferase
438 (ASMT)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Methyltransf_2
Dimerisation
Methyltransf_12
Methyltransf_25
Methyltransf_31
Motif
Other DBs
NCBI-GeneID:
438
NCBI-ProteinID:
NP_001164509
OMIM:
300015
402500
HGNC:
750
Ensembl:
ENSG00000196433
ENSG00000292336
UniProt:
P46597
Structure
PDB
PDBj
LinkDB
All DBs
Position
X:1615059..1643081, Y:1615059..1643081
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AA seq
373 aa
AA seq
DB search
MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT
ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL
ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF
PLMCDLGGTWIKLETIILSKLSQGQKTKHRVFSLIGGAGALAKECMSLYPGCKITVFDIP
EVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHT
CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFK
KTGAIYDAILARK
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atgggatcctcagaggaccaggcctatcgcctccttaatgactacgccaacggcttcatg
gtgtcccaggttctcttcgccgcctgcgagctgggcgtgtttgaccttctcgccgaggcc
ccagggcccctggacgtggcggcagtggctgcaggtgtgagggccagcgcccatgggaca
gagctcctgctggacatctgtgtgtccctgaagctgctgaaagtggagacgaggggagga
aaagctttctatcgaaacacagagctgtccagcgactacctgaccacggtcagcccgacg
tcacaatgcagcatgctgaagtacatgggcaggaccagctaccggtgctggggccacctg
gcagacgccgtgagagaaggaaggaaccagtacctggagacgtttggcgttcccgctgaa
gagctttttacggccatctacaggtccgagggcgagcggctacagttcatgcaagctctg
caggaggtctggagcgtcaacgggagaagcgtgctgaccgcctttgacctgtcagtgttc
ccacttatgtgtgaccttggtgggacatggataaagctggaaaccatcattctcagcaaa
ctatcgcaaggacagaaaaccaaacaccgcgtgttctcactcataggtggggctggagct
ctggctaaggaatgcatgtctctgtaccctggatgtaagatcaccgtttttgacatccca
gaagtggtgtggacggcaaagcagcacttctcattccaggaggaagaacagattgacttc
caggaaggggatttcttcaaagaccctcttccggaagctgatctgtacatcctggccagg
gtcctccatgactgggcagacggaaagtgctcacacctgctggagaggatctaccacact
tgcaagccaggtggtggcattctggtaattgaaagcctcctggatgaagacaggcgaggt
cctctgctcacgcagctctactctctgaacatgcttgtgcagacggaagggcaggagagg
acccccacccactaccacatgctcctctcttctgctggcttcagagacttccagtttaag
aaaacaggagccatttatgatgccattttagccaggaaataa
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