Homo sapiens (human): 4544 Help Entry 4544              CDS       T01001                                  Symbol MTNR1B, FGQTL2, MEL-1B-R, MT2 Name (RefSeq) melatonin receptor 1B   KO K04286   melatonin receptor type 1B Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04713   Circadian entrainment Disease H00409   Type 2 diabetes mellitus Drug target Agomelatine:  D02578 Melatonin:  D08170<JP> Ramelteon:  D02689<JP/US> Tasimelteon:  D09388<US> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     4544 (MTNR1B)  09150 Organismal Systems   09159 Environmental adaptation    04713 Circadian entrainment     4544 (MTNR1B)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     4544 (MTNR1B) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Others    Melatonin     4544 (MTNR1B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv 7tm_4 Motif Other DBs NCBI-GeneID:  4544 NCBI-ProteinID:  NP_005950 OMIM:  600804 HGNC:  7464 Ensembl:  ENSG00000134640 UniProt:  P49286 Structure PDBPDBj LinkDB All DBs Position 11:92969651..92984960 Genome browser AA seq 362 aa AA seqDB search MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD AL NT seq 1089 nt NT seq  +upstreamnt  +downstreamnt atgtcagagaacggctccttcgccaactgctgcgaggcgggcgggtgggcagtgcgcccg ggctggtcgggggctggcagcgcgcggccctccaggacccctcgacctccctgggtggct ccagcgctgtccgcggtgctcatcgtcaccaccgccgtggacgtcgtgggcaacctcctg gtgatcctctccgtgctcaggaaccgcaagctccggaacgcaggtaatttgttcttggtg agtctggcattggctgacctggtggtggccttctacccctacccgctaatcctcgtggcc atcttctatgacggctgggccctgggggaggagcactgcaaggccagcgcctttgtgatg ggcctgagcgtcatcggctctgtcttcaatatcactgccatcgccattaaccgctactgc tacatctgccacagcatggcctaccaccgaatctaccggcgctggcacacccctctgcac atctgcctcatctggctcctcaccgtggtggccttgctgcccaacttctttgtggggtcc ctggagtacgacccacgcatctattcctgcaccttcatccagaccgccagcacccagtac acggcggcagtggtggtcatccacttcctcctccctatcgctgtcgtgtccttctgctac ctgcgcatctgggtgctggtgcttcaggcccgcaggaaagccaagccagagagcaggctg tgcctgaagcccagcgacttgcggagctttctaaccatgtttgtggtgtttgtgatcttt gccatctgctgggctccacttaactgcatcggcctcgctgtggccatcaacccccaagaa atggctccccagatccctgaggggctatttgtcactagctacttactggcttatttcaac agctgcctgaatgccattgtctatgggctcttgaaccaaaacttccgcagggaatacaag aggatcctcttggccctttggaacccacggcactgcattcaagatgcttccaagggcagc cacgcggaggggctgcagagcccagctccacccatcattggtgtgcagcaccaggcagat gctctctag

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