KEGG   Homo sapiens (human): 4583
Entry
4583              CDS       T01001                                 
Symbol
MUC2, MLP, MUC-2, SMUC
Name
(RefSeq) mucin 2, oligomeric mucus/gel-forming
  KO
K10955  mucin-2
Organism
hsa  Homo sapiens (human)
Pathway
hsa05146  Amoebiasis
hsa05226  Gastric cancer
Network
nt06240  Transcription (cancer)
nt06261  Gastric cancer
  Element
N00250  CDX2-overexpression to transcriptional activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09162 Cancer: specific types
   05226 Gastric cancer
    4583 (MUC2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    4583 (MUC2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    4583 (MUC2)
Membrane trafficking [BR:hsa04131]
 Others
  Mucins
   Secretory mucins
    4583 (MUC2)
SSDB
Motif
Pfam: VWD C8 Mucin2_WxxW VWF TIL_OTOGL_Mucin TIL VWC Pacifastin_I
Other DBs
NCBI-GeneID: 4583
NCBI-ProteinID: NP_002448
OMIM: 158370
HGNC: 7512
Ensembl: ENSG00000198788
UniProt: Q02817 A0A3S8TMF2
Structure
LinkDB
Position
11:1074874..1110508
AA seq 5130 aa
MGLPLARLAAVCLALSLAGGSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCD
YNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTP
HYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSE
FLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDL
VPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLV
YLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLY
TPGQEITNDCEQCVCNAGRWVCKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKG
DHNDSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTA
SFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFK
TASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGR
CHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGS
CPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSC
YHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPR
ALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCN
TCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSF
SIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVV
ESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNS
WKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSC
SCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNR
SFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGA
SVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITT
RPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDD
GDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQCDVSVGFICKNEDQFGNGPFGLCY
DYKIRVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSP
PITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP
SPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT
TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP
PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTT
PSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPP
TTTTTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFH
KPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV
IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTP
ITTTNTVTPTPTPTGTQTPTPTPITTTTTMVTPTPTITSTQTPTPTPITTTTVTPTPTPT
STQRTTPTSITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPISTTT
TVTPTPTPTGTQTLTPTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTP
TLTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTKSTTPTSITTTTMVTPT
PPPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTPITTTTTVTPTPTPTGTQTPTSTPI
TTNTTVTPTPTPTGTPSTTLTPITTTTTVTPTPTPTGTQTPTSTPISTTTMVTPTPTPTG
TQTPTPTPISTTTTVTPTPTPTGTQTPTPTPITTTTTVTPTPTPTGTQTPTSTPITTTTT
VTPTPTPTGTQTPTTTPITTNTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTT
VTPITTTTTVTPTPTPTGTQSTTLTPITTTTTVTPTPTPTGIQTPTTTPISTTTTVTPTP
TPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTSTPISTTTTVTPTATPTGTQTPTLTPIT
TTTTVTPTPTPTGTKSTTPTSITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT
QTPTPTPITTTTTVTPTPTPTSTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV
TPTPTPTGTQAPTPTAITTTTTGTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQSPTP
TAITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQSTTLTPITTTTTVTPTPT
PTGTQTPTSTPITTTITVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTSTPITT
TTTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQ
TPTTTPISTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPITTTTTVT
PTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPITTTTTVTPTPTPTGTQTPTPT
PITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP
TGTQSTTLTPITTTTTVTPTPTPTGTQTPTSTPITTITTVTPTPTPTGTQTPTPTPISTT
TTVTPTPTPTGTQTPTMTPITTTTTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQT
PTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQSTTLTPITTTTTVTP
TPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTMTPITTTTTVTPTPTPTGTQTPTTTP
ISTTTTVTPTPTPTGTQTPRSTPITTTTKVTPTPTPTGTQTPTPTPITTTTTVTPTPTPT
GTQAPTPAAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQSTTLTPITTTT
TVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTSTVTPTPTPTGTQTP
TMTPITTTTTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQNPTSTPITTTTTVTPT
PTPTGTQTPTMTPITTTTTVTPTPTPTGTQAPTPTAITTTTTVTPTPTPTGTQTPTTTPI
TTTTTVTPTPIPTGTQSTTLTPITTTTTVTPTPTPTGTQTPTPIPISTTTTVTPTPTPTG
TQTPTMTPITTTTTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQTPTSTPITTTTT
VTPTPIPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTTTVTPTPTPTGTQTPT
TTPITTTTTVTPTPIPTGTQSTTLTPITTTTTVTPTPTPTSTQTPTPTPISTTTTVTPTP
TPTGTQTPTMTPITTTTTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQTPTSTPIT
TTTTVTPTPTSTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT
QTPTTTPITTTTTVTPTPTPTGTQSPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV
TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT
PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS
TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTP
TPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTL
EFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCD
CFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHY
VTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVL
IKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRL
PYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTK
RPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGSSL
ECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNT
VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC
QPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKM
VPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPC
NTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKIH
NQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGC
TKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEEKTSQREVVLSCPNGGSLTHTYTHI
ESCQCQDTVCGLPTGTSRRARRSPRHLGSG
NT seq 15393 nt   +upstreamnt  +downstreamnt
atggggctgccactagcccgcctggcggctgtgtgcctggccctgtctttggcagggggc
tcggagctccagacagagggcagaacccgaaaccacggccacaacgtctgcagcacctgg
ggcaacttccactacaagaccttcgacggggacgtcttccgcttccccggcctctgcgac
tacaacttcgcctccgactgccgaggctcctacaaggaatttgctgtgcacctgaagcgg
ggtccgggccaggctgaggcccccgccggggtggagtccatcctgctgaccatcaaggat
gacaccatctacctcacccgccacctggctgtgcttaacggggccgtggtcagcaccccg
cactacagccccgggctgctcattgagaagagcgatgcctacaccaaagtctactcccgc
gccggcctcaccctcatgtggaaccgggaggatgcactcatgctggagctggacactaag
ttccggaaccacacctgtggcctctgcggggactacaacggcctgcagagctattcagaa
ttcctctctgacggcgtgctcttcagtcccctggagtttgggaacatgcagaagatcaac
cagcccgatgtggtgtgtgaggatcccgaggaggaggtggcccccgcatcctgctccgag
caccgcgccgagtgtgagaggctgctgaccgccgaggccttcgcggactgtcaggacctg
gtgccgctggagccgtatctgcgcgcctgccagcaggaccgctgccggtgcccgggcggt
gacacctgcgtctgcagcaccgtggccgagttctcccgccagtgctcccacgccggcggc
cggcccgggaactggaggaccgccacgctctgccccaagacctgccccgggaacctggtg
tacctggagagcggctcgccctgcatggacacctgctcacacctggaggtgagcagcctg
tgcgaggagcaccgcatggacggctgtttctgcccagaaggcaccgtatatgacgacatc
ggggacagtggctgcgttcctgtgagccagtgccactgcaggctgcacggacacctgtac
acaccgggccaggagatcaccaatgactgcgagcagtgtgtctgtaacgctggccgctgg
gtgtgcaaagacctgccctgccccggcacctgtgccctggaaggcggctcccacatcacc
accttcgatgggaagacgtacaccttccacggggactgctactatgtcctggccaagggt
gaccacaacgattcctacgctctcctgggcgagctggccccctgtggctccacagacaag
cagacctgcctgaagacggtggtgctgctggctgacaagaagaagaatgtggtggtcttc
aagtccgatggcagtgtactgctcaacgagctgcaggtgaacctgccccacgtgaccgcg
agcttctctgtcttccgcccgtcttcctaccacatcatggtgagcatggccattggcgtc
cggctgcaggtgcagctggccccagtcatgcaactctttgtgacactggaccaggcctcc
caggggcaggtgcagggcctctgcgggaacttcaacggcctggaaggtgacgacttcaag
acggccagcgggctggtggaggccacgggggccggctttgccaacacctggaaggcacag
tcaagctgccatgacaagctggactggttggacgatccctgctccctgaacatcgagagc
gccaactacgccgagcactggtgctccctcctgaagaagacagagaccccctttggcagg
tgccactcggctgtggaccctgctgagtattacaagaggtgcaaatatgacacgtgtaac
tgtcagaacaatgaggactgcctgtgcgccgccctgtcctcctacgcgcgcgcctgcacc
gccaagggcgtcatgctgtggggctggcgggagcatgtctgcaacaaggatgtgggctcc
tgccccaactcgcaggtcttcctgtacaacctgaccacctgccagcagacctgccgctcc
ctctccgaggccgacagccactgtctcgagggctttgcgcctgtggacggctgcggctgc
cctgaccacaccttcctggacgagaagggccgctgcgtacccctggccaagtgctcctgt
taccaccgcggtctctacctggaggcgggggatgtggtcgtcaggcaggaagaacgatgt
gtgtgccgggatgggcggctgcactgtaggcagatccggctgatcggccagagctgcacg
gccccaaagatccacatggactgcagcaacctgactgcactggccacctcgaagccccga
gccctcagctgccagacgctggccgccggctattaccacacagagtgtgtcagtggctgt
gtgtgccccgacgggctgatggatgacggccggggtggctgcgtggtggagaaggaatgc
ccttgcgtccataacaacgacctgtattcttccggcgccaagatcaaggtggactgcaat
acctgcacctgcaagagaggacgctgggtgtgcacccaggctgtgtgccatggcacctgc
tccatttacgggagtggccactacatcacctttgatgggaagtactacgactttgacgga
cactgctcctacgtggctgttcaggactactgcggccagaactcctcactgggctcattc
agcatcatcaccgagaacgtcccctgtggcactacgggcgtcacctgctccaaggccatc
aagatcttcatggggaggacggagctgaagttggaagacaagcaccgtgtggtgatccag
cgtgatgagggtcaccacgtggcctacaccacgcgggaggtgggccagtacctggtggtg
gagtccagcacgggcatcatcgtcatctgggacaagaggaccaccgtgttcatcaagctg
gctccctcctacaagggcaccgtgtgtggcctgtgtgggaactttgaccaccgctccaac
aacgacttcaccacgcgggaccacatggtggtgagcagcgagctggacttcgggaacagc
tggaaggaggcccccacctgcccagatgtgagcaccaaccccgagccctgcagcctgaac
ccgcaccgccgctcctgggccgagaagcagtgcagcatcctcaaaagcagcgtgttcagc
atctgccacagcaaggtggaccccaagcccttctacgaggcctgtgtgcacgactcgtgc
tcctgtgacacgggtggggactgtgagtgcttctgctctgccgtggcctcctacgcccag
gagtgtaccaaagagggggcctgcgtgttctggaggacgccggacctgtgccccatattc
tgcgactactacaaccctccgcatgagtgtgagtggcactatgagccatgtgggaaccgg
agcttcgagacctgcaggaccatcaacggcatccactccaacatctccgtgtcctacctg
gagggctgctacccccggtgccccaaggacaggcccatctatgaggaggatctgaagaag
tgtgtcactgcagacaagtgtggctgctatgtcgaggacacccactacccacctggagca
tcggttcccaccgaggagacctgcaagtcctgcgtgtgtaccaactcctcccaagtcgtc
tgcaggccggaggaaggaaagattcttaaccagacccaggatggcgccttctgctactgg
gagatctgtggccccaacgggacggtggagaagcacttcaacatctgttccattacgaca
cgcccgtccaccctgaccaccttcaccaccatcaccctccccaccacccccaccaccttc
accactaccaccaccaccaccaccccgacctccagcacagttttatcaacaactccgaag
ctgtgctgcctctggtctgactggatcaatgaggaccaccccagcagtggcagcgacgac
ggtgaccgagaaacatttgatggggtctgcggggcccctgaggacatcgagtgcaggtcg
gtcaaggatccccacctcagcttggagcagctaggccagaaggtgcagtgtgatgtctct
gttgggttcatttgcaagaatgaagaccagtttggaaatggaccatttggactgtgttac
gactacaagatacgtgtcaattgttgctggcccatggataagtgtatcaccactcccagc
cctccaactaccactcccagccctccaccaaccagcacgaccacccttccaccaaccacc
acccccagccctccaaccaccaccacaaccacccctccaccaaccaccacccccagccct
ccaataaccaccacgaccacccctccaccaaccaccactcccagccctccaataagcacc
acaaccacccctccaccaaccaccactcccagccctccaaccaccactcccagccctcca
accaccactcccagccctccaacaaccaccacaaccacccctccaccaaccaccactccc
agccctccaacgactacgcccatcactccaccagccagcactaccacccttccaccaacc
accactcccagccctccaacaaccaccacaaccacccctccaccaaccaccactcccagt
cctccaacgactacgcccatcactccaccaaccagcactactacccttccaccaaccacc
actcccagccctccaccaaccaccacaaccacccctccaccaaccaccactcccagccct
ccaacaaccaccactcccagtcctccaacaatcaccacaaccacccctccaccaaccacc
actcccagccctccaacaacgaccacaaccacccctccaccaaccaccactcccagccct
ccaacgactacacccatcactccaccaaccagcactaccacccttccaccaaccaccact
cccagccctccaccaaccaccacaaccacccctccaccaaccaccactcccagccctcca
acaaccaccactcccagccctccaataaccaccacaaccacccctccaccaaccaccact
cccagctctccaataaccaccactcccagccctccaacaaccaccatgaccaccccttca
ccaaccaccacccccagctctccaataaccaccacaaccaccccttcctcaactaccact
cccagccctccaccaaccaccatgaccaccccttcaccaaccaccactcccagccctcca
acaaccaccacgaccacccttccaccaaccaccacttccagccctctaacaactactcct
ctacctccatcaataactcctcctacattttcaccattctcaacgacaacccctactacc
ccatgcgtgcctctctgcaattggactggctggctggattctggaaaacccaactttcac
aaaccaggtggagacacagaattgattggagacgtctgtggaccaggctgggcagctaac
atctcttgcagagccaccatgtatcctgatgttcccattggacagcttggacaaacagtg
gtgtgtgatgtctctgtggggctgatatgcaaaaatgaagaccaaaagccaggtggggtc
atccctatggccttctgcctcaactacgagatcaacgttcagtgctgtgagtgtgtcacc
caacccaccaccatgacaaccaccaccacagagaacccaactccgacaccaatcaccacc
accactacggtgaccccaaccccaacacccaccagcacacagagtacaacaccaacaccc
atcaccaccaccaatacggtaaccccaaccccaacccccactggcacacagaccccaacc
ccgacacccatcaccaccaccaccactatggtgaccccaaccccaacaatcaccagcaca
cagaccccaaccccgacacccatcaccaccactacggtgaccccaaccccaacacccacc
agcacacagagaacaacaccgacatccatcaccaccaccaccacggtgaccccaacccca
acacccaccggcacacagaccccaaccacgacacccatcaccaccaccaccacggtgacc
ccaaccccaacacccaccggcacacagaccccaacaacgacacccatcagcaccaccacc
acggtgaccccaaccccaacacccactggaacacagaccctaaccccaacacccatcacc
accaccactacggtgaccccaacccctacacccaccggcacacagaccccaacatcgaca
cccatcaccaccaccactacggtgaccccaacaccaacacccactggcacacagacccca
accctgacacccatcaccaccaccactacggtgaccccaaccccaacacccaccggcaca
cagaccccaaccacgacacccatcaccaccaccactacggtgaccccaaccccaacaccc
accggcacaaagagtacaaccccgacatccatcaccaccaccactatggtgaccccaacc
ccaccacccactggcacacagaccccaaccacgacacccatcaccaccaccactacggtg
accccaaccccaacacccaccggcacacagaccccaaccccgacacccatcaccaccacc
accacggtgaccccaaccccaacacccaccggcacacagaccccaacatcgacacccatc
accaccaacactacggtgaccccaaccccaacaccaaccggcacaccgagtacaaccctg
acacccatcaccaccaccactacggtgaccccaaccccaacacccaccggcacacagacc
ccaacatcgacacccatcagcaccaccactatggtgaccccaaccccaacacccaccggc
acacagaccccaacccctacacccatctccaccaccactacggtgaccccaaccccaaca
cccaccggcacacagaccccaaccccgacacccatcaccaccaccaccacggtgacccca
accccaacacccaccggcacacagaccccaacatcgacacccatcaccaccaccactacg
gtgaccccaaccccaacacccaccggcacacagaccccaaccacgacacccatcaccacc
aacaccacggtgaccccaaccccgacacccaccggcacacagaccccaaccacggtactc
atcaccaccaccactacgatgacaccaaccccaacacccaccagcacaaagagtacaacc
gtgacacccatcaccaccaccactactgtgaccccaaccccaacacccaccggcacacag
agtacaaccctgacacccatcaccaccaccactacggtgaccccaaccccaacacccacc
ggcatacagaccccaacaacgacacccatcagcaccaccaccaccgtgaccccaacccca
acacccaccggcacacagaccccaacatcgacacccatcaccaccaccactacggtgacc
ccaacccctacacccactggcacacagaccccaacatcgacacccatcagcaccaccact
acggtgaccccaacagcaacacccaccggcacacagaccccaaccctgacacccatcacc
accaccactacggtgaccccaaccccaacacccaccggcacaaagagtacaaccccgaca
tccatcaccaccaccactacggtgaccccaaccccaacacccactggcacacagacccca
accacgacacccatcaccaccaccaccacggtgaccccaaccccaacacccaccggcaca
cagaccccaaccccgacacccatcaccaccaccaccacggtgaccccaaccccaacaccc
accagcacacagaccccaacatcgacacccatcaccaccaccactacggtgaccccaacc
ccaacacccactggcacacagaccccaaccacgacacccattaccacgaccaccacggtg
accccaaccccaacacccaccggcacacaggccccaaccccaacagccatcaccaccacc
actacggggaccccaaccccaacacccaccggcacacagaccccaaccacgacacccatc
accaccaccactacggtgacaccaaccccaacacccaccggcacacagtccccaacccca
acagccatcaccaccaccactacggtgaccccaaccccaacacccaccggcacacagacc
ccaaccacgacacccatcaccaccaccaccacggtgaccccaaccccgacacccaccggc
acacagagtacaaccctgacacccatcaccaccaccaccacggtgacaccaaccccaaca
cccactggcacacagaccccaacatcgacacccatcaccaccaccattacggtgacccca
accccaacacccaccggcacacagaccccaaccccgacacccatctccaccaccactacg
gtgaccccaaccccaacacccaccggcacacagaccccaacatcgacacccatcaccacc
accaccacggtgaccccaaccccaacacccaccggcacacagaccccaacaacgacaccc
atcagcaccaccaccacggtgaccccaaccccaacacccaccggcacacagaccccaaca
tcgacacccatcaccaccaccaccacggtgaccccaaccccaacacccaccggcacacag
accccaaccacgacacccatcagcaccaccaccacggtgaccccaaccccaacacccacc
ggcacacagaccccaacatcgacacccatcaccaccaccaccacggtgaccccaacccca
acacccaccggcacacagaccccaaccccgacacccatcaccaccaccaccacggtgacc
ccaaccccaacacccaccggcacacagaccccaacatcgacacccatcaccaccaccacc
acggtgaccccaaccccaacacccaccggcacacagaccccaaccccgacacccatcacc
accaccaccacggtgaccccaaccccaacacccaccggcacacagaccccaaccccgaca
cccatcaccaccaccaccacggtgaccccaaccccaacacccaccggcacacagacccca
acatcgacacccatcaccaccaccactacggtgaccccaaccccaacacccaccggcaca
cagaccccaaccacgacacccatcaccaccaccaccacggtgaccccaaccccaacaccc
actggcacacagagtacaaccctgacacccatcaccaccaccaccacggtgacaccaacc
ccaacacccaccggcacacagaccccaacatcgacacccatcaccaccatcactacggtg
accccaaccccaacacccaccggcacacagaccccaaccccgacacccatctccaccacc
actacagtgaccccaaccccaacacccaccggcacacagaccccaaccatgacacccatc
accaccaccaccacggtgaccccaaccccaacacccaccggcacacagaccccaacaacg
acacccatcagcaccaccaccacggtgaccccaaccccaacacccaccggcacacagacc
ccaacatcgacacccatcaccaccaccactacggtgaccccaaccccaacacccaccggc
acacagaccccaaccacgacacccatcaccaccaccaccacggtgaccccaaccccaaca
cccaccggcacacagagtacaaccctgacacccatcaccaccaccaccacggtgacacca
accccaacacccaccggcacacagaccccaaccccgacacccatctccaccaccactacg
gtgaccccaaccccaacacccaccggcacacagaccccaaccatgacacccatcaccacc
accaccacggtgaccccaaccccaacacccaccggcacacagaccccaacaacgacaccc
atcagcaccaccaccacggtgaccccaaccccaacacccaccggcacacagaccccaaga
tcgacacccatcaccaccaccactaaggtgaccccaaccccaacacccaccggcacacag
accccaaccccgacacccatcaccaccaccaccacggtgaccccaaccccaacacccact
ggcacacaggccccaaccccagcagccatcaccaccaccagtacggtgaccccaacccca
acacccaccggcacacagaccccaaccacgacacccatcaccaccaccaccacggtgacc
ccaaccccaacacccaccggcacacagagtacaaccctgacacccatcaccaccaccacc
acggtgacaccaaccccaacacccaccggcacacagaccccaacatcgacacccatcacc
accaccactacggtgaccccaaccccaacacccaccggcacacagaccccaaccccgaca
cccatctccaccaccagtacggtgaccccaaccccaacacccaccggcacacagacccca
accatgacacccatcaccaccaccaccacggtgaccccaaccccaacacccaccggcaca
cagaccccaacaacgacacccatcagcaccaccaccacggtgaccccaaccccaacaccc
accggcacacagaacccaacatcgacacccatcaccaccaccactacggtgaccccaacc
ccaacacccaccggcacacagaccccaaccatgacacccatcaccaccaccaccacggtg
accccaaccccaacacccactggcacacaggccccaaccccaacagccatcaccaccacc
actacggtgaccccaaccccaacacccaccggcacacagaccccaaccacgacacccatc
accaccaccaccacggtgaccccaaccccaatacccaccggcacacagagtacaaccctg
acacccatcaccaccaccaccacggtgacaccaaccccaacacccaccggcacacagacc
ccaaccccgatacccatctccaccaccactacggtgaccccaaccccaacacccaccggc
acacagaccccaaccatgacacccatcaccaccaccaccacggtgaccccaaccccaaca
cccaccggcacacagaccccaacaacgacacccatcagcaccaccaccacggtgacccca
accccaacacccaccggcacacagaccccaacatcgacacccatcaccaccaccactacg
gtgaccccaaccccaatacccaccggcacacagaccccaaccacgacacccatcaccacc
accaccacggtgaccccaaccccaacacccactggcacacaggccccaaccccaacagcc
atcaccaccaccactacggtgaccccaaccccaacacccaccggcacacagaccccaacc
acgacacccatcaccaccaccaccacggtgaccccaaccccaatacccaccggcacacag
agtacaaccctgacacccatcaccaccaccaccacggtgacaccaaccccaacacccacc
agcacacagaccccaaccccgacacccatctccaccaccactacggtgaccccaacccca
acacccaccggcacacagaccccaaccatgacacccatcaccaccaccaccacggtgacc
ccaaccccaacacccaccggcacacagaccccaacaacgacacccatcagcaccaccacc
acggtgaccccaaccccaacacccaccggcacacagaccccaacatcgacacccatcacc
accaccactacagtgaccccaaccccaacatccaccggcacacagaccccaaccacgaca
cccatcaccaccaccaccacggtgaccccaaccccaacacccactggcacacaggcccca
accccaacagccatcaccaccaccagtacggtgaccccaaccccaacacccaccggcaca
cagaccccaaccacgacacccatcaccaccaccactacggtgacaccaaccccaacaccc
accggcacacagtccccaaccccaacagccatcaccaccaccactacggtgaccccaacc
ccaacacccaccggcacacagaccccaacatcgacacccatcaccaccaccactacggtg
accccaaccccaacacccaccggcacacagaccccaaccccgacacccatctccaccacc
actacggtgaccccaaccccaacacccaccggcacacagaccccaaccacgacacccatc
accaccaccaccacggtgaccccaaccccgacacccaccggcacacagaccccaaccacg
gtactcatcaccaccaccactacgatgaccccaaccccaacacccaccagcacaaagagt
acaaccgtgacacccatcaccaccacaactacggtgaccgcaaccccaacacccaccggc
acacagaccccaaccatgatacccatcagcaccaccactacggtgaccccaaccccaaca
cccaccactggaagcacggggccccccacccacacaagcacagcacccattgctgagttg
accacatccaatcctccgcctgagtcctcaacccctcagacctctcggtccacctcttcc
cctctcacggagtcaaccacccttctgagtaccctaccacctgccattgagatgaccagc
acggccccaccctccacacccacggcacccacgaccacgagcggaggccacacactgtct
ccaccgcccagcaccaccacgtcccctccaggcacccccactcgcggtaccacgaccggg
tcatcttcagcccccacccccagcactgtgcagacgaccaccaccagtgcctggacccca
acgccgaccccactctccacacccagcatcatcaggaccacaggcctgaggccctaccct
tcctctgtgcttatctgctgtgtcctgaacgacacctactacgcaccaggtgaggaggtg
tacaacggcacatacggagacacctgttatttcgtcaactgctcactgagctgtacgttg
gagttctataactggtcctgcccatccacgccctccccaacacccacgccctccaagtcg
acgcccacgccttccaagccatcgtccacgccctccaagccgacgcccggcaccaagccc
cccgagtgcccagactttgatcctcccagacaggagaacgagacttggtggctgtgcgac
tgcttcatggccacgtgcaagtacaacaacacggtggagatcgtgaaggtggagtgtgag
ccgccgcccatgcccacctgctccaacggcctccaacccgtgcgcgtcgaggaccccgac
ggctgctgctggcactgggagtgcgactgctactgcacgggctggggcgacccgcactat
gtcaccttcgacggactctactacagctaccagggcaactgcacctacgtgctggtggag
gagatcagcccctccgtggacaacttcggagtttacatcgacaactaccactgcgatccc
aacgacaaggtgtcctgtccccgcaccctcatcgtgcgccacgagacccaggaggtgctg
atcaagaccgtgcatatgatgcccatgcaggtgcaggtgcaggtgaacaggcaggcggtg
gcactgccctacaagaagtacgggctggaggtgtaccagtctggcatcaactacgtggtg
gacatccccgagctgggtgtcctcgtctcctacaatggcctgtccttctccgtcaggctg
ccctaccaccggtttggcaacaacaccaagggccagtgtggcacctgcaccaacaccacc
tccgacgactgcattctgcccagcggggagatcgtctccaactgtgaggctgcggctgac
cagtggctggtgaacgacccctccaagccacactgcccccacagcagctccacgaccaag
cgcccggccgtcactgtgcccgggggcggtaaaacgaccccacacaaggactgcacccca
tctcccctctgccagctcatcaaggacagcctgtttgcccagtgccacgcactggtgccc
ccgcagcactactacgatgcctgcgtgttcgacagctgcttcatgccgggctcgagcctg
gagtgcgccagtctgcaggcctacgcagccctctgtgcccagcagaacatctgcctcgac
tggcggaaccacacgcatggggcctgcttggtggagtgcccatctcacagggagtaccag
gcctgtggccctgcagaagagcccacgtgcaaatccagctcctcccagcagaacaacaca
gtcctggtggaaggctgcttctgtcctgagggcaccatgaactacgctcctggctttgat
gtctgcgtgaagacctgcggctgtgtgggacctgacaatgtgcccagagagtttggggag
cacttcgagttcgactgcaagaactgtgtctgcctggagggtggaagtggcatcatctgc
caacccaagaggtgcagccagaagcccgttacccactgcgtggaagacggcacctacctc
gccacggaggtcaaccctgccgacacctgctgcaacattaccgtctgcaagtgcaacacc
agcctgtgcaaagagaagccctccgtgtgcccgctgggattcgaagtgaagagcaagatg
gtgcctggaaggtgctgtcctttctactggtgtgagtccaagggggtgtgtgttcacggg
aatgctgagtaccagcccggttctccagtttattcctccaagtgccaggactgcgtgtgc
acggacaaggtggacaacaacaccctgctcaacgtcatcgcctgcacccacgtgccctgc
aacacctcctgcagccctggcttcgaactcatggaggcccccggggagtgctgtaagaag
tgtgaacagacgcactgtatcatcaaacggcccgacaaccagcacgtcatcctgaagccc
ggggacttcaagagcgacccgaagaacaactgcacattcttcagctgcgtgaagatccac
aaccagctcatctcgtccgtctccaacatcacctgccccaactttgatgccagcatttgc
atcccgggctccatcacattcatgcccaatggatgctgcaagacctgcacccctcgcaat
gagaccagggtgccctgctccaccgtccccgtcaccacggaggtttcgtacgccggctgc
accaagaccgtcctcatgaatcattgctccgggtcctgcgggacatttgtcatgtactcg
gccaaggcccaggccctggaccacagctgctcctgctgcaaagaggagaaaaccagccag
cgtgaggtggtcctgagctgccccaatggcggctcgctgacacacacctacacccacatc
gagagctgccagtgccaggacaccgtctgcgggctccccaccggcacctcccgccgggcc
cggcgctcccctaggcatctggggagcgggtga

KEGG   Homo sapiens (human): 1015
Entry
1015              CDS       T01001                                 
Symbol
CDH17, CDH16, HPT-1, HPT1
Name
(RefSeq) cadherin 17
  KO
K06811  cadherin 17, LI cadherin
Organism
hsa  Homo sapiens (human)
Pathway
hsa05226  Gastric cancer
Network
nt06240  Transcription (cancer)
nt06261  Gastric cancer
  Element
N00250  CDX2-overexpression to transcriptional activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09162 Cancer: specific types
   05226 Gastric cancer
    1015 (CDH17)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    1015 (CDH17)
Cell adhesion molecules [BR:hsa04515]
 Cadherins
  Major cadherins
   1015 (CDH17)
SSDB
Motif
Pfam: Cadherin Cadherin_FAT4_N Cadherin_4 RET_CLD1 Cadherin_CELSR2_9th RibLong SKG6
Other DBs
NCBI-GeneID: 1015
NCBI-ProteinID: NP_001138135
OMIM: 603017
HGNC: 1756
Ensembl: ENSG00000079112
UniProt: Q12864
Structure
LinkDB
Position
8:complement(94127162..94217278)
AA seq 832 aa
MILQAHLHSLCLLMLYLATGYGQEGKFSGPLKPMTFSIYEGQEPSQIIFQFKANPPAVTF
ELTGETDNIFVIEREGLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDIN
DNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYF
QINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWK
APKPVEMVENSTDPHPIKITQVRWNDPGAQYSLVDKEKLPRFPFSIDQEGDIYVTQPLDR
EEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSPVTVFEVQENERLGNSIG
TLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLKKQDTPQYNL
TIEVSDKDFKTLCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNIGSTILTIQATDADEP
FTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAVSNIVFKAENPEPLV
FGVKYNASSFAKFTLIVTDVNEAPQFSQHVFQAKVSEDVAIGTKVGNVTAKDPEGLDISY
SLRGDTRGWLKIDHVTGEIFSVAPLDREAGSPYRVQVVATEVGGSSLSSVSEFHLILMDV
NDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQHLFRGPHFTFSLGSGSLQNDWEVSK
INGTHARLSTRHTEFEEREYVVLIRINDGGRPPLEGIVSLPVTFCSCVEGSCFRPAGHQT
GIPTVGMAVGILLTTLLVIGIILAVVFIRIKKDKGKDNVESAQASEVKPLRS
NT seq 2499 nt   +upstreamnt  +downstreamnt
atgatacttcaggcccatcttcactccctgtgtcttcttatgctttatttggcaactgga
tatggccaagaggggaagtttagtggacccctgaaacccatgacattttctatttatgaa
ggccaagaaccgagtcaaattatattccagtttaaggccaatcctcctgctgtgactttt
gaactaactggggagacagacaacatatttgtgatagaacgggagggacttctgtattac
aacagagccttggacagggaaacaagatctactcacaatctccaggttgcagccctggac
gctaatggaattatagtggagggtccagtccctatcaccataaaagtgaaggacatcaac
gacaatcgacccacgtttctccagtcaaagtacgaaggctcagtaaggcagaactctcgc
ccaggaaagcccttcttgtatgtcaatgccacagacctggatgatccggccactcccaat
ggccagctttattaccagattgtcatccagcttcccatgatcaacaatgtcatgtacttt
cagatcaacaacaaaacgggagccatctctcttacccgagagggatctcaggaattgaat
cctgctaagaatccttcctataatctggtgatctcagtgaaggacatgggaggccagagt
gagaattccttcagtgataccacatctgtggatatcatagtgacagagaatatttggaaa
gcaccaaaacctgtggagatggtggaaaactcaactgatcctcaccccatcaaaatcact
caggtgcggtggaatgatcccggtgcacaatattccttagttgacaaagagaagctgcca
agattcccattttcaattgaccaggaaggagatatttacgtgactcagcccttggaccga
gaagaaaaggatgcatatgttttttatgcagttgcaaaggatgagtacggaaaaccactt
tcatatccgctggaaattcatgtaaaagttaaagatattaatgataatccacctacatgt
ccgtcaccagtaaccgtatttgaggtccaggagaatgaacgactgggtaacagtatcggg
acccttactgcacatgacagggatgaagaaaatactgccaacagttttctaaactacagg
attgtggagcaaactcccaaacttcccatggatggactcttcctaatccaaacctatgct
ggaatgttacagttagctaaacagtccttgaagaagcaagatactcctcagtacaactta
acgatagaggtgtctgacaaagatttcaagaccctttgttttgtgcaaatcaacgttatt
gatatcaatgatcagatccccatctttgaaaaatcagattatggaaacctgactcttgct
gaagacacaaacattgggtccaccatcttaaccatccaggccactgatgctgatgagcca
tttactgggagttctaaaattctgtatcatatcataaagggagacagtgagggacgcctg
ggggttgacacagatccccataccaacaccggatatgtcataattaaaaagcctcttgat
tttgaaacagcagctgtttccaacattgtgttcaaagcagaaaatcctgagcctctagtg
tttggtgtgaagtacaatgcaagttcttttgccaagttcacgcttattgtgacagatgtg
aatgaagcacctcaattttcccaacacgtattccaagcgaaagtcagtgaggatgtagct
ataggcactaaagtgggcaatgtgactgccaaggatccagaaggtctggacataagctat
tcactgaggggagacacaagaggttggcttaaaattgaccacgtgactggtgagatcttt
agtgtggctccattggacagagaagccggaagtccatatcgggtacaagtggtggccaca
gaagtaggggggtcttccttgagctctgtgtcagagttccacctgatccttatggatgtg
aatgacaaccctcccaggctagccaaggactacacgggcttgttcttctgccatcccctc
agtgcacctggaagtctcattttcgaggctactgatgatgatcagcacttatttcggggt
ccccattttacattttccctcggcagtggaagcttacaaaacgactgggaagtttccaaa
atcaatggtactcatgcccgactgtctaccaggcacacagagtttgaggagagggagtat
gtcgtcttgatccgcatcaatgatgggggtcggccacccttggaaggcattgtttcttta
ccagttacattctgcagttgtgtggaaggaagttgtttccggccagcaggtcaccagact
gggatacccactgtgggcatggcagttggtatactgctgaccacccttctggtgattggt
ataattttagcagttgtgtttatccgcataaagaaggataaaggcaaagataatgttgaa
agtgctcaagcatctgaagtcaaacctctgagaagctga

KEGG   Homo sapiens (human): 83998
Entry
83998             CDS       T01001                                 
Symbol
REG4, GISP, REG-IV, RELP
Name
(RefSeq) regenerating family member 4
  KO
K22244  regenerating islet-derived protein 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa05226  Gastric cancer
Network
nt06240  Transcription (cancer)
nt06261  Gastric cancer
  Element
N00250  CDX2-overexpression to transcriptional activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09162 Cancer: specific types
   05226 Gastric cancer
    83998 (REG4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    83998 (REG4)
  09183 Protein families: signaling and cellular processes
   04091 Lectins [BR:hsa04091]
    83998 (REG4)
Peptidases and inhibitors [BR:hsa01002]
 Peptidase inhibitors
  Family I63
   83998 (REG4)
Lectins [BR:hsa04091]
 C-Type lectins
  Others
   83998 (REG4)
SSDB
Motif
Pfam: Lectin_C
Other DBs
NCBI-GeneID: 83998
NCBI-ProteinID: NP_001152824
OMIM: 609846
HGNC: 22977
Ensembl: ENSG00000134193
UniProt: Q9BYZ8
Structure
LinkDB
Position
1:complement(119794017..119811460)
AA seq 158 aa
MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAELECQS
YGNGAHLASILSLKEASTIAEYISGYQRSQPIWIGLHDPQKRQQWQWIDGAMYLYRSWSG
KSMGGNKHCAEMSSNNNFLTWSSNECNKRQHFLCKYRP
NT seq 477 nt   +upstreamnt  +downstreamnt
atggcttccagaagcatgcggctgctcctattgctgagctgcctggccaaaacaggagtc
ctgggtgatatcatcatgagacccagctgtgctcctggatggttttaccacaagtccaat
tgctatggttacttcaggaagctgaggaactggtctgatgccgagctcgagtgtcagtct
tacggaaacggagcccacctggcatctatcctgagtttaaaggaagccagcaccatagca
gagtacataagtggctatcagagaagccagccgatatggattggcctgcacgacccacag
aagaggcagcagtggcagtggattgatggggccatgtatctgtacagatcctggtctggc
aagtccatgggtgggaacaagcactgtgctgagatgagctccaataacaactttttaact
tggagcagcaacgaatgcaacaagcgccaacacttcctgtgcaagtaccgaccatag

KEGG   Homo sapiens (human): 5243
Entry
5243              CDS       T01001                                 
Symbol
ABCB1, ABC20, CD243, CLCS, ENPAT, GP170, MDR1, P-GP, PGY1, p-170
Name
(RefSeq) ATP binding cassette subfamily B member 1
  KO
K05658  ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa02010  ABC transporters
hsa04976  Bile secretion
hsa05206  MicroRNAs in cancer
hsa05226  Gastric cancer
Network
nt06240  Transcription (cancer)
nt06261  Gastric cancer
  Element
N00250  CDX2-overexpression to transcriptional activation
Disease
H01227  Inflammatory bowel disease (IBD)
H01529  Avascular necrosis of femoral head
H02831  Acute transient encephalopathy
Drug target
Biricodar dicitrate: D03128
Elacridar hydrochloride: D03968
Encequidar (DG03103): D11782 D11783
Tariquidar: D06008
Tesmilifene hydrochloride: D06084
Valspodar: D06277
Zosuquidar trihydrochloride: D06387
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    5243 (ABCB1)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    5243 (ABCB1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    5243 (ABCB1)
  09162 Cancer: specific types
   05226 Gastric cancer
    5243 (ABCB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    5243 (ABCB1)
   04147 Exosome [BR:hsa04147]
    5243 (ABCB1)
   04090 CD molecules [BR:hsa04090]
    5243 (ABCB1)
Enzymes [BR:hsa01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.2  ABC-type xenobiotic transporter
     5243 (ABCB1)
Transporters [BR:hsa02000]
 ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB1, 4, 5 subgroups
    5243 (ABCB1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   5243 (ABCB1)
CD molecules [BR:hsa04090]
 Proteins
  5243 (ABCB1)
SSDB
Motif
Pfam: ABC_membrane ABC_tran SMC_N ABC_ATPase AAA_22 Rad17 RsgA_GTPase AAA_16 AAA_5 Zeta_toxin AAA_29 AAA_14 G-alpha AAA_7 AAA_15 DUF815 DUF2207_C NTPase_1
Other DBs
NCBI-GeneID: 5243
NCBI-ProteinID: NP_000918
OMIM: 171050
HGNC: 40
Ensembl: ENSG00000085563
UniProt: P08183 A4D1D2
Structure
LinkDB
Position
7:complement(87503017..87713295)
AA seq 1280 aa
MDLEGDRNGGAKKKNFFKLNNKSEKDKKEKKPTVSVFSMFRYSNWLDKLYMVVGTLAAII
HGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRSDINDTGFFMNLEEDMTRYAYYYSG
IGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVS
KINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFT
DKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIG
AAFLLIYASYALAFWYGTTLVLSGEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARG
AAYEIFKIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSG
QTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLF
ATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIA
IARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAG
FDDGVIVEKGNHDELMKEKGIYFKLVTMQTAGNEVELENAADESKSEIDALEMSSNDSRS
SLIRKRSTRRSVRGSQAQDRKLSTKEALDESIPPVSFWRIMKLNLTEWPYFVVGVFCAII
NGGLQPAFAIIFSKIIGVFTRIDDPETKRQNSNLFSLLFLALGIISFITFFLQGFTFGKA
GEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNI
ANLGTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEA
IENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKAHIFGITFSFTQAMMYFSYAGCFRFG
AYLVAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTPLIDS
YSTEGLMPNTLEGNVTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVV
QLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVV
SQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLD
EATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQL
LAQKGIYFSMVSVQAGTKRQ
NT seq 3843 nt   +upstreamnt  +downstreamnt
atggatcttgaaggggaccgcaatggaggagcaaagaagaagaacttttttaaactgaac
aataaaagtgaaaaagataagaaggaaaagaaaccaactgtcagtgtattttcaatgttt
cgctattcaaattggcttgacaagttgtatatggtggtgggaactttggctgccatcatc
catggggctggacttcctctcatgatgctggtgtttggagaaatgacagatatctttgca
aatgcaggaaatttagaagatctgatgtcaaacatcactaatagaagtgatatcaatgat
acagggttcttcatgaatctggaggaagacatgaccaggtatgcctattattacagtgga
attggtgctggggtgctggttgctgcttacattcaggtttcattttggtgcctggcagct
ggaagacaaatacacaaaattagaaaacagttttttcatgctataatgcgacaggagata
ggctggtttgatgtgcacgatgttggggagcttaacacccgacttacagatgatgtctcc
aagattaatgaaggaattggtgacaaaattggaatgttctttcagtcaatggcaacattt
ttcactgggtttatagtaggatttacacgtggttggaagctaacccttgtgattttggcc
atcagtcctgttcttggactgtcagctgctgtctgggcaaagatactatcttcatttact
gataaagaactcttagcgtatgcaaaagctggagcagtagctgaagaggtcttggcagca
attagaactgtgattgcatttggaggacaaaagaaagaacttgaaaggtacaacaaaaat
ttagaagaagctaaaagaattgggataaagaaagctattacagccaatatttctataggt
gctgctttcctgctgatctatgcatcttatgctctggccttctggtatgggaccaccttg
gtcctctcaggggaatattctattggacaagtactcactgtattcttttctgtattaatt
ggggcttttagtgttggacaggcatctccaagcattgaagcatttgcaaatgcaagagga
gcagcttatgaaatcttcaagataattgataataagccaagtattgacagctattcgaag
agtgggcacaaaccagataatattaagggaaatttggaattcagaaatgttcacttcagt
tacccatctcgaaaagaagttaagatcttgaagggtctgaacctgaaggtgcagagtggg
cagacggtggccctggttggaaacagtggctgtgggaagagcacaacagtccagctgatg
cagaggctctatgaccccacagaggggatggtcagtgttgatggacaggatattaggacc
ataaatgtaaggtttctacgggaaatcattggtgtggtgagtcaggaacctgtattgttt
gccaccacgatagctgaaaacattcgctatggccgtgaaaatgtcaccatggatgagatt
gagaaagctgtcaaggaagccaatgcctatgactttatcatgaaactgcctcataaattt
gacaccctggttggagagagaggggcccagttgagtggtgggcagaagcagaggatcgcc
attgcacgtgccctggttcgcaaccccaagatcctcctgctggatgaggccacgtcagcc
ttggacacagaaagcgaagcagtggttcaggtggctctggataaggccagaaaaggtcgg
accaccattgtgatagctcatcgtttgtctacagttcgtaatgctgacgtcatcgctggt
ttcgatgatggagtcattgtggagaaaggaaatcatgatgaactcatgaaagagaaaggc
atttacttcaaacttgtcacaatgcagacagcaggaaatgaagttgaattagaaaatgca
gctgatgaatccaaaagtgaaattgatgccttggaaatgtcttcaaatgattcaagatcc
agtctaataagaaaaagatcaactcgtaggagtgtccgtggatcacaagcccaagacaga
aagcttagtaccaaagaggctctggatgaaagtatacctccagtttccttttggaggatt
atgaagctaaatttaactgaatggccttattttgttgttggtgtattttgtgccattata
aatggaggcctgcaaccagcatttgcaataatattttcaaagattataggggtttttaca
agaattgatgatcctgaaacaaaacgacagaatagtaacttgttttcactattgtttcta
gcccttggaattatttcttttattacatttttccttcagggtttcacatttggcaaagct
ggagagatcctcaccaagcggctccgatacatggttttccgatccatgctcagacaggat
gtgagttggtttgatgaccctaaaaacaccactggagcattgactaccaggctcgccaat
gatgctgctcaagttaaaggggctataggttccaggcttgctgtaattacccagaatata
gcaaatcttgggacaggaataattatatccttcatctatggttggcaactaacactgtta
ctcttagcaattgtacccatcattgcaatagcaggagttgttgaaatgaaaatgttgtct
ggacaagcactgaaagataagaaagaactagaaggttctgggaagatcgctactgaagca
atagaaaacttccgaaccgttgtttctttgactcaggagcagaagtttgaacatatgtat
gctcagagtttgcaggtaccatacagaaactctttgaggaaagcacacatctttggaatt
acattttccttcacccaggcaatgatgtatttttcctatgctggatgtttccggtttgga
gcctacttggtggcacataaactcatgagctttgaggatgttctgttagtattttcagct
gttgtctttggtgccatggccgtggggcaagtcagttcatttgctcctgactatgccaaa
gccaaaatatcagcagcccacatcatcatgatcattgaaaaaacccctttgattgacagc
tacagcacggaaggcctaatgccgaacacattggaaggaaatgtcacatttggtgaagtt
gtattcaactatcccacccgaccggacatcccagtgcttcagggactgagcctggaggtg
aagaagggccagacgctggctctggtgggcagcagtggctgtgggaagagcacagtggtc
cagctcctggagcggttctacgaccccttggcagggaaagtgctgcttgatggcaaagaa
ataaagcgactgaatgttcagtggctccgagcacacctgggcatcgtgtcccaggagccc
atcctgtttgactgcagcattgctgagaacattgcctatggagacaacagccgggtggtg
tcacaggaagagattgtgagggcagcaaaggaggccaacatacatgccttcatcgagtca
ctgcctaataaatatagcactaaagtaggagacaaaggaactcagctctctggtggccag
aaacaacgcattgccatagctcgtgcccttgttagacagcctcatattttgcttttggat
gaagccacgtcagctctggatacagaaagtgaaaaggttgtccaagaagccctggacaaa
gccagagaaggccgcacctgcattgtgattgctcaccgcctgtccaccatccagaatgca
gacttaatagtggtgtttcagaatggcagagtcaaggagcatggcacgcatcagcagctg
ctggcacagaaaggcatctatttttcaatggtcagtgtccaggctggaacaaagcgccag
tga

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