KEGG   NETWORK: N02000
Entry
N02000                      Network                                
Name
Clasical cadherin to Hippo signaling pathway
Definition
CDH == CDH -> CTNNB -> CTNNA -> (WWC1+NF2) -> ((MST1/2+SAV1)+(LATS1/2+MOB)) -| (YAP/TAZ+TEAD)
  Expanded
(999,1000,1001,1002,1003,1004,1005,1006,1007,1008,1009,1010,1012,1013,1014,1015,1016,28513,28316,64405,64072,64403,60437) == (999,1000,1001,1002,1003,1004,1005,1006,1007,1008,1009,1010,1012,1013,1014,1015,1016,28513,28316,64405,64072,64403,60437) -> 1499 -> (1495,1496,29119) -> (23286+4771) -> ((6789,6788)+60485+(9113,26524)+(55233,92597)) -| ((10413,25937)+(7003,8463,7005,7004))
Class
nt06549 Cadherin signaling
Type
Reference
Pathway
hsa04390 Hippo signaling pathway   
hsa04519 Cadherin signaling   
Gene
999  CDH1; cadherin 1
1000  CDH2; cadherin 2
1001  CDH3; cadherin 3
1002  CDH4; cadherin 4
1003  CDH5; cadherin 5
1004  CDH6; cadherin 6
1005  CDH7; cadherin 7
1006  CDH8; cadherin 8
1007  CDH9; cadherin 9
1008  CDH10; cadherin 10
1009  CDH11; cadherin 11
1010  CDH12; cadherin 12
1012  CDH13; cadherin 13
1013  CDH15; cadherin 15
1014  CDH16; cadherin 16
1015  CDH17; cadherin 17
1016  CDH18; cadherin 18
28513  CDH19; cadherin 19
28316  CDH20; cadherin 20
64405  CDH22; cadherin 22
64072  CDH23; cadherin related 23
64403  CDH24; cadherin 24
60437  CDH26; cadherin 26
1499  CTNNB1; catenin beta 1
1495  CTNNA1; catenin alpha 1
1496  CTNNA2; catenin alpha 2
29119  CTNNA3; catenin alpha 3
23286  WWC1; WW and C2 domain containing 1
4771  NF2; NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor
6789  STK4; serine/threonine kinase 4
6788  STK3; serine/threonine kinase 3
60485  SAV1; salvador family WW domain containing protein 1
9113  LATS1; large tumor suppressor kinase 1
26524  LATS2; large tumor suppressor kinase 2
55233  MOB1A; MOB kinase activator 1A
92597  MOB1B; MOB kinase activator 1B
10413  YAP1; Yes1 associated transcriptional regulator
25937  WWTR1; WW domain containing transcription regulator 1
7003  TEAD1; TEA domain transcription factor 1
8463  TEAD2; TEA domain transcription factor 2
7005  TEAD3; TEA domain transcription factor 3
7004  TEAD4; TEA domain transcription factor 4
Reference
PMID:37255594
  Authors
Lin WH, Cooper LM, Anastasiadis PZ
  Title
Cadherins and catenins in cancer: connecting cancer pathways and tumor microenvironment.
  Journal
Front Cell Dev Biol 11:1137013 (2023)
DOI:10.3389/fcell.2023.1137013
LinkDB

DBGET integrated database retrieval system