Homo sapiens (human): 4686
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Entry
4686 CDS
T01001
Symbol
NCBP1, CBP80, NCBP, Sto1
Name
(RefSeq) nuclear cap binding protein subunit 1
KO
K12882
nuclear cap-binding protein subunit 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa03013
Nucleocytoplasmic transport
hsa03015
mRNA surveillance pathway
hsa03040
Spliceosome
hsa05014
Amyotrophic lateral sclerosis
Network
nt06464
Amyotrophic lateral sclerosis
Element
N01152
Nuclear export of mRNA
N01153
Mutation-caused aberrant GLE1 to nuclear export of mRNA
Drug target
Obefazimod:
D12345
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09121 Transcription
03040 Spliceosome
4686 (NCBP1)
09122 Translation
03013 Nucleocytoplasmic transport
4686 (NCBP1)
03015 mRNA surveillance pathway
4686 (NCBP1)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
4686 (NCBP1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
4686 (NCBP1)
03041 Spliceosome [BR:
hsa03041
]
4686 (NCBP1)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA processing factors
5' end processing
Cap binding complex
4686 (NCBP1)
Spliceosome [BR:
hsa03041
]
Common components
Common spliceosomal components
Cap binding complex
4686 (NCBP1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MIF4G_like_2
MIF4G
MIF4G_like
Cob_adeno_trans
DUF2524
Motif
Other DBs
NCBI-GeneID:
4686
NCBI-ProteinID:
NP_002477
OMIM:
600469
HGNC:
7658
Ensembl:
ENSG00000136937
Pharos:
Q09161
(Tbio)
UniProt:
Q09161
Structure
PDB
PDBj
LinkDB
All DBs
Position
9:97633821..97673748
Genome browser
AA seq
790 aa
AA seq
DB search
MSRRRHSDENDGGQPHKRRKTSDANETEDHLESLICKVGEKSACSLESNLEGLAGVLEAD
LPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN
YNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWV
GKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLK
KDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEG
PVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELF
QLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHH
LSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPAN
PTCIYKYGDESSNSLPGHSVALCLAVAFKSKATNDEIFSILKDVPNPNQDDDDDEGFSFN
PLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQM
IAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELE
EAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMI
LTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILA
VFQQFCALQA
NT seq
2373 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcggcggcggcacagcgacgagaacgacggtgggcagcctcacaaaaggagaaag
acctctgatgcaaatgaaactgaagatcatttggaatctttaatatgtaaagtaggagaa
aagagtgcctgctctttggagagcaacctagaaggcttggctggtgttttggaagctgat
cttcctaactacaagagcaagatcttaaggcttctttgtacagttgcacgcctattacct
gagaagctgacaatttatacaacattagttggactactgaatgccaggaattacaatttt
ggtggagaatttgtagaagccatgattcgtcaacttaaagaatcattgaaagcaaacaat
tataatgaagccgtgtatttggtccgttttttatctgatcttgtgaattgtcatgtgatt
gccgccccatcaatggttgctatgtttgaaaattttgtaagcgtaactcaggaagaagat
gtacctcaggtgcgacgagattggtatgtgtatgcatttctgtcatctttgccctgggtt
ggaaaggagttgtacgaaaagaaagatgcagagatggaccgcatctttgccaacactgaa
agctatcttaaaagacgccaaaagactcatgtacccatgttacaggtatggactgctgat
aaaccacatccacaagaagagtatttagattgcctgtgggcccagattcagaaattgaaa
aaggatcgctggcaggaacggcacatcctaagaccttatcttgcctttgacagcatcctg
tgtgaagcactgcagcacaatctgcctccttttacaccacctcctcacactgaagattca
gtgtacccaatgccaagggtcatcttcagaatgtttgattacacagatgatcccgagggt
cctgtcatgccagggagtcattcagtggaaagatttgtaatagaagagaatcttcactgc
atcattaagtcccactggaaggaaaggaagacttgtgctgcacagttagtgagctatcca
gggaagaacaagatccccttgaactaccacatagttgaggtgatctttgcagagctgttt
caacttccagcaccccctcacattgatgtgatgtacacaacactcctcattgaactgtgc
aaacttcaacctggctctctaccccaagttcttgcacaggcaactgaaatgctatacatg
cgtttggacacaatgaacactacctgtgtagacaggtttattaattggttttctcatcat
ctaagtaacttccagttccgttggagctgggaagattggtcagattgtcttagtcaagat
cctgaaagtcccaaaccgaagtttgtaagagaagttctagaaaaatgtatgaggttgtct
taccatcagcgtatattagatattgttcctcctaccttctcagctctgtgtcctgcaaac
ccaacctgcatttacaagtatggagatgaaagtagcaattctcttcctggacattctgtt
gccctctgtttagctgttgcctttaaaagtaaggcaaccaatgatgaaatcttcagcatt
ctgaaagatgtaccaaatcctaaccaggatgatgacgacgatgaaggattcagttttaac
ccattgaaaatagaagtctttgtacagactctgctacacttggcagccaaatcattcagc
cactccttcagtgctcttgcaaagtttcatgaagtcttcaaaaccctagctgaaagtgat
gaaggaaagttacatgtgctaagagttatgtttgaggtctggaggaaccatccacagatg
attgctgtactagtggataagatgattcgtacacaaatagttgattgtgctgccgtagca
aattggatcttctcttcagaactatctcgtgactttaccagattgtttgtttgggaaatt
ttgcactctacaattcgtaagatgaacaaacatgtcctgaagatccagaaagagctggaa
gaagctaaagagaaacttgctaggcaacacaaacggcgaagtgatgatgacgacagaagc
agtgacaggaaagacggggttcttgaggaacaaatagaacgacttcaggaaaaagtggaa
tctgctcagagtgaacaaaagaatcttttcctcgttatatttcagcggtttatcatgatc
ttgaccgagcacctagtacgatgcgaaactgatgggaccagtgtattaacaccatggtat
aagaactgtatagagaggctgcagcagatcttcctacagcatcaccaaataatccagcag
tacatggtgaccctggagaaccttctcttcactgctgaattagaccctcatatcttggcc
gtgttccagcagttctgtgccctgcaggcctaa
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