Homo sapiens (human): 4791
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Entry
4791 CDS
T01001
Symbol
NFKB2, CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p100, p49/p100, p52
Name
(RefSeq) nuclear factor kappa B subunit 2
KO
K04469
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
hsa04064
NF-kappa B signaling pathway
hsa04380
Osteoclast differentiation
hsa04625
C-type lectin receptor signaling pathway
hsa05134
Legionellosis
hsa05166
Human T-cell leukemia virus 1 infection
hsa05169
Epstein-Barr virus infection
hsa05200
Pathways in cancer
hsa05203
Viral carcinogenesis
hsa05224
Breast cancer
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06223
TNF signaling
nt06516
TNF signaling
Element
N00505
CD40-NFKB signaling pathway
N00506
HTLV-1 Tax to CD40-NFKB signaling pathway
Disease
H00088
Common variable immunodeficiency
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
4791 (NFKB2)
04064 NF-kappa B signaling pathway
4791 (NFKB2)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
4791 (NFKB2)
09158 Development and regeneration
04380 Osteoclast differentiation
4791 (NFKB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
4791 (NFKB2)
05203 Viral carcinogenesis
4791 (NFKB2)
09162 Cancer: specific types
05224 Breast cancer
4791 (NFKB2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
4791 (NFKB2)
05169 Epstein-Barr virus infection
4791 (NFKB2)
09171 Infectious disease: bacterial
05134 Legionellosis
4791 (NFKB2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
4791 (NFKB2)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
beta-Scaffold factors with minor groove contacts
RHR (Rel homology region) Rel/Ankyrin
4791 (NFKB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RHD_DNA_bind
RHD_dimer
Ank_2
Ank
Ank_3
Ank_5
Ank_4
Death
Motif
Other DBs
NCBI-GeneID:
4791
NCBI-ProteinID:
NP_001070962
OMIM:
164012
HGNC:
7795
Ensembl:
ENSG00000077150
Pharos:
Q00653
(Tchem)
UniProt:
Q00653
Structure
PDB
LinkDB
All DBs
Position
10:102394110..102402529
Genome browser
AA seq
900 aa
AA seq
DB search
MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
EEGVRLLRGPETRDKLPSTAEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atggagagttgctacaacccaggtctggatggtattattgaatatgatgatttcaaattg
aactcctccattgtggaacccaaggagccagccccagaaacagctgatggcccctacctg
gtgatcgtggaacagcctaagcagagaggcttccgatttcgatatggctgtgaaggcccc
tcccatggaggactgcccggtgcctccagtgagaagggccgaaagacctatcccactgtc
aagatctgtaactacgagggaccagccaagatcgaggtggacctggtaacacacagtgac
ccacctcgtgctcatgcccacagtctggtgggcaagcaatgctcggagctggggatctgc
gccgtttctgtggggcccaaggacatgactgcccaatttaacaacctgggtgtcctgcat
gtgactaagaagaacatgatggggactatgatacaaaaacttcagaggcagcggctccgc
tctaggccccagggccttacggaggccgagcagcgggagctggagcaagaggccaaagaa
ctgaagaaggtgatggatctgagtatagtgcggctgcgcttctctgccttccttagagcc
agtgatggctccttctccctgcccctgaagccagtcatctcccagcccatccatgacagc
aaatctccgggggcatcaaacctgaagatttctcgaatggacaagacagcaggctctgtg
cggggtggagatgaagtttatctgctttgtgacaaggtgcagaaagatgacattgaggtt
cggttctatgaggatgatgagaatggatggcaggcctttggggacttctctcccacagat
gtgcataaacagtatgccattgtgttccggacacccccctatcacaagatgaagattgag
cggcctgtaacagtgtttctgcaactgaaacgcaagcgaggaggggacgtgtctgattcc
aaacagttcacctattaccctctggtggaagacaaggaagaggtgcagcggaagcggagg
aaggccttgcccaccttctcccagcccttcgggggtggctcccacatgggtggaggctct
gggggtgcagccgggggctacggaggagctggaggaggtggcagcctcggtttcttcccc
tcctccctggcctacagcccctaccagtccggcgcgggccccatgggctgctacccggga
ggcgggggcggggcgcagatggccgccacggtgcccagcagggactccggggaggaagcc
gcggagccgagcgccccctccaggaccccccagtgcgagccgcaggccccggagatgctg
cagcgagctcgagagtacaacgcgcgcctgttcggcctggcgcagcgcagcgcccgagcc
ctactcgactacggcgtcaccgcggacgcgcgcgcgctgctggcgggacagcgccacctg
ctgacggcgcaggacgagaacggagacacaccactgcacctagccatcatccacgggcag
accagtgtcattgagcagatagtctatgtcatccaccacgcccaggacctcggcgttgtc
aacctcaccaaccacctgcaccagacgcccctgcacctggcggtgatcacggggcagacg
agtgtggtgagctttctgctgcgggtaggtgcagacccagctctgctggatcggcatgga
gactcagccatgcatctggcgctgcgggcaggcgctggtgctcctgagctgctgcgtgca
ctgcttcagagtggagctcctgctgtgccccagctgttgcatatgcctgactttgaggga
ctgtatccagtacacctggcggtccgagcccgaagccctgagtgcctggatctgctggtg
gacagtggggctgaagtggaggccacagagcggcaggggggacgaacagccttgcatcta
gccacagagatggaggagctggggttggtcacccatctggtcaccaagctccgggccaac
gtgaacgctcgcacctttgcgggaaacacacccctgcacctggcagctggactggggtac
ccgaccctcacccgcctccttctgaaggctggtgctgacatccatgctgaaaacgaggag
cccctgtgcccactgccttcaccccctacctctgatagcgactcggactctgaagggcct
gagaaggacacccgaagcagcttccggggccacacgcctcttgacctcacttgcagcacc
aaggtgaagaccttgctgctaaatgctgctcagaacaccatggagccacccctgaccccg
cccagcccagcagggccgggactgtcacttggtgatacagctctgcagaacctggagcag
ctgctagacgggccagaagcccagggcagctgggcagagctggcagagcgtctggggctg
cgcagcctggtagacacgtaccgacagacaacctcacccagtggcagcctcctgcgcagc
tacgagctggctggcggggacctggcaggtctactggaggccctgtctgacatgggccta
gaggagggagtgaggctgctgaggggtccagaaacccgagacaagctgcccagcacagca
gaggtgaaggaagacagtgcgtacgggagccagtcagtggagcaggaggcagagaagctg
ggcccaccccctgagccaccaggagggctctgccacgggcacccccagcctcaggtgcac
tga
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