| Entry |
|
|---|
| Symbol |
NT5E, CALJA, CD73, E5NT, NT, NT5, NTE, eN, eNT
|
|---|
| Name |
(RefSeq) 5'-nucleotidase ecto
|
|---|
| KO |
|
|---|
| Organism |
|
|---|
| Pathway |
| hsa00760 | Nicotinate and nicotinamide metabolism |
|
|---|
| Module |
| hsa_M00958 | Adenine ribonucleotide degradation, AMP => Urate |
| hsa_M00959 | Guanine ribonucleotide degradation, GMP => Urate |
|
|---|
| Network |
|
|---|
| Element |
| N01418 | Purine salvage pathway, adenine to AMP |
| N01421 | Purine salvage pathway, hypoxanthine/guanine to IMP/GMP |
| N01910 | Adenine nucleotide conversion |
|
|---|
| Disease |
| H00824 | Calcification of joints and arteries |
|
|---|
| Drug target |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
4907 (NT5E)
00240 Pyrimidine metabolism
4907 (NT5E)
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
4907 (NT5E)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:hsa04090]
4907 (NT5E)
00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
4907 (NT5E)
Enzymes [BR:hsa01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.5 5'-nucleotidase
4907 (NT5E)
CD molecules [BR:hsa04090]
Proteins
4907 (NT5E)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
Enzymes
4907 (NT5E)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| Structure |
|
|---|
| LinkDB |
|
|---|
| Position |
6:85450083..85495784
|
|---|
| AA seq |
574 aa
MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGG
VARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEF
DNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKE
TPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVV
GGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNV
ISSHGNPILLNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNM
GNLICDAMINNNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGT
FDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCR
VPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYP
AVEGRIKFSTGSHCHGSFSLIFLSLWAVIFVLYQ |
|---|
| NT seq |
1725 nt +upstreamnt +downstreamnt
atgtgtccccgagccgcgcgggcgcccgcgacgctactcctcgccctgggcgcggtgctg
tggcctgcggctggcgcctgggagcttacgattttgcacaccaacgacgtgcacagccgg
ctggagcagaccagcgaggactccagcaagtgcgtcaacgccagccgctgcatgggtggc
gtggctcggctcttcaccaaggttcagcagatccgccgcgccgaacccaacgtgctgctg
ctggacgccggcgaccagtaccagggcactatctggttcaccgtgtacaagggcgccgag
gtggcgcacttcatgaacgccctgcgctacgatgccatggcactgggaaatcatgaattt
gataatggtgtggaaggactgatcgagccactcctcaaagaggccaaatttccaattctg
agtgcaaacattaaagcaaaggggccactagcatctcaaatatcaggactttatttgcca
tataaagttcttcctgttggtgatgaagttgtgggaatcgttggatacacttccaaagaa
accccttttctctcaaatccagggacaaatttagtgtttgaagatgaaatcactgcatta
caacctgaagtagataagttaaaaactctaaatgtgaacaaaattattgcactgggacat
tcgggttttgaaatggataaactcatcgctcagaaagtgaggggtgtggacgtcgtggtg
ggaggacactccaacacatttctttacacaggcaatccaccttccaaagaggtgcctgct
gggaagtacccattcatagtcacttctgatgatgggcggaaggttcctgtagtccaggcc
tatgcttttggcaaatacctaggctatctgaagatcgagtttgatgaaagaggaaacgtc
atctcttcccatggaaatcccattcttctaaacagcagcattcctgaagatccaagcata
aaagcagacattaacaaatggaggataaaattggataattattctacccaggaattaggg
aaaacaattgtctatctggatggctcctctcaatcatgccgctttagagaatgcaacatg
ggcaacctgatttgtgatgcaatgattaacaacaacctgagacacacggatgaaatgttc
tggaaccacgtatccatgtgcattttaaatggaggtggtatccggtcgcccattgatgaa
cgcaacaatggcacaattacctgggagaacctggctgctgtattgccctttggaggcaca
tttgacctagtccagttaaaaggttccaccctgaagaaggcctttgagcatagcgtgcac
cgctacggccagtccactggagagttcctgcaggtgggcggaatccatgtggtgtatgat
ctttcccgaaaacctggagacagagtagtcaaattagatgttctttgcaccaagtgtcga
gtgcccagttatgaccctctcaaaatggacgaggtatataaggtgatcctcccaaacttc
ctggccaatggtggagatgggttccagatgataaaagatgaattattaagacatgactct
ggtgaccaagatatcaacgtggtttctacatatatctccaaaatgaaagtaatttatcca
gcagttgaaggtcggatcaagttttccacaggaagtcactgccatggaagcttttcttta
atatttctttcactttgggcagtgatctttgttttataccaatag |
|---|
