Homo sapiens (human): 4919
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Entry
4919 CDS
T01001
Symbol
ROR1, NTRKR1, dJ537F10.1
Name
(RefSeq) receptor tyrosine kinase like orphan receptor 1
KO
K05122
receptor tyrosine kinase-like orphan receptor 1 [EC:
2.7.10.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04310
Wnt signaling pathway
Network
nt06505
WNT signaling
Element
N01427
WNT5A-ROR signaling pathway
Disease
H00605
Deafness, autosomal recessive
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
4919 (ROR1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
4919 (ROR1)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
4919 (ROR1)
Protein kinases [BR:
hsa01001
]
Receptor tyrosine kinases (RTK)
ROR family
4919 (ROR1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Kringle
I-set
Ig_3
Fz
Ig_2
ig
V-set
TMEM154
Haspin_kinase
FlaX
Motif
Other DBs
NCBI-GeneID:
4919
NCBI-ProteinID:
NP_005003
OMIM:
602336
HGNC:
10256
Ensembl:
ENSG00000185483
UniProt:
Q01973
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:63774017..64181498
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AA seq
937 aa
AA seq
DB search
MHRPRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTL
DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN
LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACAR
FIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSS
VPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIG
IPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHS
YCRNPGNQKEAPWCFTLDENFKSDLCDIPACDSKDSKEKNKMEILYILVPSVAIPLAIAL
LFFFICVCRNNQKSSSAPVQRQPKHVRGQNVEMSMLNAYKPKSKAKELPLSAVRFMEELG
ECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLG
AVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIA
AGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSLLPIRWMP
PEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPR
MYSLMTECWNEIPSRRPRFKDIHVRLRSWEGLSSHTSSTTPSGGNATTQTTSLSASPVSN
LSNPRYPNYMFPSQGITPQGQIAGFIGPPIPQNQRFIPINGYPIPPGYAAFPAAHYQPTG
PPRVIQHCPPPKSRSPSSASGSTSTGHVTSLPSSGSNQEANIPLLPHMSIPNHPGGMGIT
VFGNKSQKPYKIDSKQASLLGDANIHGHTESMISAEL
NT seq
2814 nt
NT seq
+upstream
nt +downstream
nt
atgcaccggccgcgccgccgcgggacgcgcccgccgctcctggcgctgctggccgcgctg
ctgctggccgcacgcggggctgctgcccaagaaacagagctgtcagtcagtgctgaatta
gtgcctacctcatcatggaacatctcaagtgaactcaacaaagattcttacctgaccctc
gatgaaccaatgaataacatcaccacgtctctgggccagacagcagaactgcactgcaaa
gtctctgggaatccacctcccaccatccgctggttcaaaaatgatgctcctgtggtccag
gagccccggaggctctcctttcggtccaccatctatggctctcggctgcggattagaaac
ctcgacaccacagacacaggctacttccagtgcgtggcaacaaacggcaaggaggtggtt
tcttccactggagtcttgtttgtcaagtttggcccccctcccactgcaagtccaggatac
tcagatgagtatgaagaagatggattctgtcagccatacagagggattgcatgtgcaaga
tttattggcaaccgcaccgtctatatggagtctttgcacatgcaaggggaaatagaaaat
cagatcacagctgccttcactatgattggcacttccagtcacttatctgataagtgttct
cagttcgccattccttccctgtgccactatgccttcccgtactgcgatgaaacttcatcc
gtcccaaagccccgtgacttgtgtcgcgatgaatgtgaaatcctggagaatgtcctgtgt
caaacagagtacatttttgcaagatcaaatcccatgattctgatgaggctgaaactgcca
aactgtgaagatctcccccagccagagagcccagaagctgcgaactgtatccggattgga
attcccatggcagatcctataaataaaaatcacaagtgttataacagcacaggtgtggac
taccgggggaccgtcagtgtgaccaaatcagggcgccagtgccagccatggaattcccag
tatccccacacacacactttcaccgcccttcgtttcccagagctgaatggaggccattcc
tactgccgcaacccagggaatcaaaaggaagctccctggtgcttcaccttggatgaaaac
tttaagtctgatctgtgtgacatcccagcgtgcgattcaaaggattccaaggagaagaat
aaaatggaaatcctgtacatactagtgccaagtgtggccattcccctggccattgcttta
ctcttcttcttcatttgcgtctgtcggaataaccagaagtcatcgtcggcaccagtccag
aggcaaccaaaacacgtcagaggtcaaaatgtagagatgtcaatgctgaatgcatataaa
cccaagagcaaggctaaagagctacctctttctgctgtacgctttatggaagaattgggt
gagtgtgcctttggaaaaatctataaaggccatctctatctcccaggcatggaccatgct
cagctggttgctatcaagaccttgaaagactataacaacccccagcaatggacggaattt
caacaagaagcctccctaatggcagaactgcaccaccccaatattgtctgccttctaggt
gccgtcactcaggaacaacctgtgtgcatgctttttgagtatattaatcagggggatctc
catgagttcctcatcatgagatccccacactctgatgttggctgcagcagtgatgaagat
gggactgtgaaatccagcctggaccacggagattttctgcacattgcaattcagattgca
gctggcatggaatacctgtctagtcacttctttgtccacaaggaccttgcagctcgcaat
attttaatcggagagcaacttcatgtaaagatttcagacttggggctttccagagaaatt
tactccgctgattactacagggtccagagtaagtccttgctgcccattcgctggatgccc
cctgaagccatcatgtatggcaaattctcttctgattcagatatctggtcctttggggtt
gtcttgtgggagattttcagttttggactccagccatattatggattcagtaaccaggaa
gtgattgagatggtgagaaaacggcagctcttaccatgctctgaagactgcccacccaga
atgtacagcctcatgacagagtgctggaatgagattccttctaggagaccaagatttaaa
gatattcacgtccggcttcggtcctgggagggactctcaagtcacacaagctctactact
ccttcagggggaaatgccaccacacagacaacctccctcagtgccagcccagtgagtaat
ctcagtaaccccagatatcctaattacatgttcccgagccagggtattacaccacagggc
cagattgctggtttcattggcccgccaatacctcagaaccagcgattcattcccatcaat
ggatacccaatacctcctggatatgcagcgtttccagctgcccactaccagccaacaggt
cctcccagagtgattcagcactgcccacctcccaagagtcggtccccaagcagtgccagt
gggtcgactagcactggccatgtgactagcttgccctcatcaggatccaatcaggaagca
aatattcctttactaccacacatgtcaattccaaatcatcctggtggaatgggtatcacc
gtttttggcaacaaatctcaaaaaccctacaaaattgactcaaagcaagcatctttacta
ggagacgccaatattcatggacacaccgaatctatgatttctgcagaactgtaa
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