KEGG   NETWORK: N01427
Entry
N01427                      Network                                
Name
WNT5A-ROR signaling pathway
Definition
WNT5A -> (FZD,(ROR1,ROR2)) -> DVL
  Expanded
7474 -> ((8321,2535,7976,8322,7855,8323,8324,8325,8326,11211),(4919,4920)) -> (1855,1856,1857)
Class
nt06505 WNT signaling
Type
Reference
Pathway
hsa04310  Wnt signaling pathway
Gene
7474  WNT5A; Wnt family member 5A
8321  FZD1; frizzled class receptor 1
2535  FZD2; frizzled class receptor 2
7976  FZD3; frizzled class receptor 3
8322  FZD4; frizzled class receptor 4
7855  FZD5; frizzled class receptor 5
8323  FZD6; frizzled class receptor 6
8324  FZD7; frizzled class receptor 7
8325  FZD8; frizzled class receptor 8
8326  FZD9; frizzled class receptor 9
11211  FZD10; frizzled class receptor 10
4919  ROR1; receptor tyrosine kinase like orphan receptor 1
4920  ROR2; receptor tyrosine kinase like orphan receptor 2
1855  DVL1; dishevelled segment polarity protein 1
1856  DVL2; dishevelled segment polarity protein 2
1857  DVL3; dishevelled segment polarity protein 3
Reference
PMID:33445713
  Authors
Menck K, Heinrichs S, Baden C, Bleckmann A
  Title
The WNT/ROR Pathway in Cancer: From Signaling to Therapeutic Intervention.
  Journal
Cells 10:142 (2021)
DOI:10.3390/cells10010142
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