Homo sapiens (human): 493869
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Entry
493869 CDS
T01001
Symbol
GPX8, EPLA847, GPx-8, GSHPx-8, UNQ847
Name
(RefSeq) glutathione peroxidase 8 (putative)
KO
K00432
glutathione peroxidase [EC:
1.11.1.9
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00480
Glutathione metabolism
hsa01100
Metabolic pathways
hsa04918
Thyroid hormone synthesis
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05022
Pathways of neurodegeneration - multiple diseases
Network
nt06026
Glutathione biosynthesis
nt06525
Ferroptosis
Element
N01589
Glutathione biosynthesis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00480 Glutathione metabolism
493869 (GPX8)
09150 Organismal Systems
09152 Endocrine system
04918 Thyroid hormone synthesis
493869 (GPX8)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
493869 (GPX8)
05016 Huntington disease
493869 (GPX8)
05022 Pathways of neurodegeneration - multiple diseases
493869 (GPX8)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.9 glutathione peroxidase
493869 (GPX8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GSHPx
AhpC-TSA
Redoxin
Motif
Other DBs
NCBI-GeneID:
493869
NCBI-ProteinID:
NP_001008398
OMIM:
617172
HGNC:
33100
Ensembl:
ENSG00000164294
UniProt:
Q8TED1
Structure
PDB
PDBj
LinkDB
All DBs
Position
5:55160171..55167297
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AA seq
209 aa
AA seq
DB search
MEPLAAYPLKCSGPRAKVFAVLLSIVLCTVTLFLLQLKFLKPKINSFYAFEVKDAKGRTV
SLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSK
EVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKF
WKPEEPIEVIRPDIAALVRQVIIKKKEDL
NT seq
630 nt
NT seq
+upstream
nt +downstream
nt
atggagcctcttgcagcttacccgctaaaatgttccgggcccagagcaaaggtatttgca
gttttgctgtctatagttctatgcacagtaacgctatttcttctacaactaaaattcctc
aaacctaaaatcaacagcttttatgcctttgaagtgaaggatgcaaaaggaagaactgtt
tctctggaaaagtataaaggcaaagtttcactagttgtaaacgtggccagtgactgccaa
ctcacagacagaaattacttagggctgaaggaactgcacaaagagtttggaccatcccac
ttcagcgtgttggcttttccctgcaatcagtttggagaatcggagccccgcccaagcaag
gaagtagaatcttttgcaagaaaaaactacggagtaactttccccatcttccacaagatt
aagattctaggatctgaaggagaacctgcatttagatttcttgttgattcttcaaagaag
gaaccaaggtggaatttttggaagtatcttgtcaaccctgagggtcaagttgtgaagttc
tggaagccagaggagcccattgaagtcatcaggcctgacatagcagctctggttagacaa
gtgatcataaaaaagaaagaggatctatga
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integrated database retrieval system
