Homo sapiens (human): 4939
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Entry
4939 CDS
T01001
Symbol
OAS2
Name
(RefSeq) 2'-5'-oligoadenylate synthetase 2
KO
K14216
2'-5'-oligoadenylate synthetase [EC:
2.7.7.84
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04621
NOD-like receptor signaling pathway
hsa05160
Hepatitis C
hsa05162
Measles
hsa05164
Influenza A
hsa05168
Herpes simplex virus 1 infection
hsa05169
Epstein-Barr virus infection
hsa05171
Coronavirus disease - COVID-19
Network
nt06163
Hepatitis C virus (HCV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06170
Influenza A virus (IAV)
nt06263
Hepatocellular carcinoma
nt06521
NLR signaling
Element
N00273
HCV NS5A to oligoadenylate synthetase (OAS)/RNase L pathway
N00515
Oligoadenylate synthetase (OAS)/RNase L pathway
N00574
HSV US11 to oligoadenylate synthetase (OAS)/RNase L pathway
N00724
IAV NS1 to oligoadenylate synthetase (OAS)/RNase L pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
4939 (OAS2)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
4939 (OAS2)
05171 Coronavirus disease - COVID-19
4939 (OAS2)
05164 Influenza A
4939 (OAS2)
05162 Measles
4939 (OAS2)
05168 Herpes simplex virus 1 infection
4939 (OAS2)
05169 Epstein-Barr virus infection
4939 (OAS2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.84 2'-5' oligoadenylate synthase
4939 (OAS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
OAS1_C
NTP_transf_2
SMODS
DZF_N
DcrB
Motif
Other DBs
NCBI-GeneID:
4939
NCBI-ProteinID:
NP_058197
OMIM:
603350
HGNC:
8087
Ensembl:
ENSG00000111335
UniProt:
P29728
LinkDB
All DBs
Position
12:112978519..113011723
Genome browser
AA seq
719 aa
AA seq
DB search
MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG
GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI
QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC
FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD
NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN
VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK
CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS
YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF
DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK
DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT
QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA
KEWLSSPCFKDGTGNPIPPWKVPTMQTPGSCGARIHPIVNEMFSSRSHRILNNNSKRNF
NT seq
2160 nt
NT seq
+upstream
nt +downstream
nt
atgggaaatggggagtcccagctgtcctcggtgcctgctcagaagctgggttggtttatc
caggaatacctgaagccctacgaagaatgtcagacactgatcgacgagatggtgaacacc
atctgtgacgtcctgcaggaacccgaacagttccccctggtgcagggagtggccataggt
ggctcctatggacggaaaacagtcttaagaggcaactccgatggtacccttgtcctcttc
ttcagtgacttaaaacaattccaggatcagaagagaagccaacgtgacatcctcgataaa
actggggataagctgaagttctgtctgttcacgaagtggttgaaaaacaatttcgagatc
cagaagtcccttgatgggttcaccatccaggtgttcacaaaaaatcagagaatctctttc
gaggtgctggccgccttcaacgctctgagcttaaatgataatcccagcccctggatctat
cgagagctcaaaagatccttggataagacaaatgccagtcctggtgagtttgcagtctgc
ttcactgaactccagcagaagttttttgacaaccgtcctggaaaactaaaggatttgatc
ctcttgataaagcactggcatcaacagtgccagaaaaaaatcaaggatttaccctcgctg
tctccgtatgccctggagctgcttacggtgtatgcctgggaacaggggtgcagaaaagac
aactttgacattgctgaaggcgtcagaaccgtactggagctgatcaaatgccaggagaag
ctgtgtatctattggatggtcaactacaactttgaagatgagaccatcaggaacatcctg
ctgcaccagctccaatcagcgaggccagtaatcttggatccagttgacccaaccaataat
gtgagtggagataaaatatgctggcaatggctgaaaaaagaagctcaaacctggttgact
tctcccaacctggataatgagttacctgcaccatcttggaatgttctgcctgcaccactc
ttcacgaccccaggccaccttctggataagttcatcaaggagtttctccagcccaacaaa
tgcttcctagagcagattgacagtgctgttaacatcatccgtacattccttaaagaaaac
tgcttccgacaatcaacagccaagatccagattgtccggggaggatcaaccgccaaaggc
acagctctgaagactggctctgatgccgatctcgtcgtgttccataactcacttaaaagc
tacacctcccaaaaaaacgagcggcacaaaatcgtcaaggaaatccatgaacagctgaaa
gccttttggagggagaaggaggaggagcttgaagtcagctttgagcctcccaagtggaag
gctcccagggtgctgagcttctctctgaaatccaaagtcctcaacgaaagtgtcagcttt
gatgtgcttcctgcctttaatgcactgggtcagctgagttctggctccacacccagcccc
gaggtttatgcagggctcattgatctgtataaatcctcggacctcccgggaggagagttt
tctacctgtttcacagtcctgcagcgaaacttcattcgctcccggcccaccaaactaaag
gatttaattcgcctggtgaagcactggtacaaagagtgtgaaaggaaactgaagccaaag
gggtctttgcccccaaagtatgccttggagctgctcaccatctatgcctgggagcagggg
agtggagtgccggattttgacactgcagaaggtttccggacagtcctggagctggtcaca
caatatcagcagctctgcatcttctggaaggtcaattacaactttgaagatgagaccgtg
aggaagtttctactgagccagttgcagaaaaccaggcctgtgatcttggacccagccgaa
cccacaggtgacgtgggtggaggggaccgttggtgttggcatcttctggcaaaagaagca
aaggaatggttatcctctccctgcttcaaggatgggactggaaacccaataccaccttgg
aaagtgccgacaatgcagacaccaggaagttgtggagctaggatccatcctattgtcaat
gagatgttctcatccagaagccatagaatcctgaataataattctaaaagaaacttctag
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