Homo sapiens (human): 50487 Help Entry 50487             CDS       T01001                                  Symbol PLA2G3, GIII-SPLA2, SPLA2III, sPLA2-III Name (RefSeq) phospholipase A2 group III   KO K01047   secretory phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04014   Ras signaling pathway hsa04270   Vascular smooth muscle contraction hsa04972   Pancreatic secretion hsa04975   Fat digestion and absorption Drug target Varespladib (DG01394):  D06283 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     50487 (PLA2G3)    00565 Ether lipid metabolism     50487 (PLA2G3)    00590 Arachidonic acid metabolism     50487 (PLA2G3)    00591 Linoleic acid metabolism     50487 (PLA2G3)    00592 alpha-Linolenic acid metabolism     50487 (PLA2G3)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     50487 (PLA2G3)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     50487 (PLA2G3)   09154 Digestive system    04972 Pancreatic secretion     50487 (PLA2G3)    04975 Fat digestion and absorption     50487 (PLA2G3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hsa03036]     50487 (PLA2G3) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      50487 (PLA2G3) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Centriole proteins     50487 (PLA2G3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Phospholip_A2_2 Chromadorea_ALT Motif Other DBs NCBI-GeneID:  50487 NCBI-ProteinID:  NP_056530 OMIM:  611651 HGNC:  17934 Ensembl:  ENSG00000100078 UniProt:  Q9NZ20 LinkDB All DBs Position 22:complement(31134807..31140508) Genome browser AA seq 509 aa AA seqDB search MGVQAGLFGMLGFLGVALGGSPALRWYRTSCHLTKAVPGNPLGYLSFLAKDAQGLALIHA RWDAHRRLQSCSWEDEPELTAAYGALCAHETAWGSFIHTPGPELQRALATLQSQWEACRA LEESPAGARKKRAAGQSGVPGGGHQREKRGWTMPGTLWCGVGDSAGNSSELGVFQGPDLC CREHDRCPQNISPLQYNYGIRNYRFHTISHCDCDTRFQQCLQNQHDSISDIVGVAFFNVL EIPCFVLEEQEACVAWYWWGGCRMYGTVPLARLQPRTFYNASWSSRATSPTPSSRSPAPP KPRQKQHLRKGPPHQKGSKRPSKANTTALQDPMVSPRLDVAPTGLQGPQGGLKPQGARWV CRSFRRHLDQCEHQIGPREIEFQLLNSAQEPLFHCNCTRRLARFLRLHSPPEVTNMLWEL LGTTCFKLAPPLDCVEGKNCSRDPRAIRVSARHLRRLQQRRHQLQDKGTDERQPWPSEPL RGPMSFYNQCLQLTQAARRPDRQQKSWSQ NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggggttcaggcagggctgtttgggatgctgggcttcctgggggtggccctggggggc tcccctgccctccgctggtacaggacctcctgccacttgaccaaggccgtccctggcaac ccactggggtacctgagcttcctggccaaggatgctcagggactggccctgatccatgcc cgctgggatgcgcataggaggctgcagtcatgtagctgggaggatgagccggagctcacc gcagcctacggtgctctctgtgctcatgagactgcctggggctccttcatccacaccccc ggacccgagctgcagagagcactggccactcttcagagtcagtgggaggcatgccgagcg cttgaggagagtccagcaggggccaggaagaagcgagcagcagggcagagtggagtccct ggtggagggcaccagcgagagaagagaggatggaccatgcctggcacactgtggtgtgga gttggagattctgctgggaactcctcggagctgggggtcttccagggacctgatctctgt tgccgggaacatgaccgctgcccacagaacatctcacccttgcagtacaactatggcatc cgaaactaccgattccacaccatctcccactgtgactgtgacaccaggtttcagcaatgc ctacagaatcagcacgactccatctcggacatcgtgggcgtggccttcttcaacgtgctg gagatcccctgctttgtgctggaggagcaggaggcgtgtgtggcgtggtactggtggggc gggtgtaggatgtacggcacagtgcccctcgctcgcctgcagcccaggaccttctacaat gcctcctggagctcccgggccacctccccaactcccagctcccggagcccagcccctccc aagcctcgacagaagcagcaccttcggaaggggccaccacatcagaaagggtccaagcgc cccagcaaagccaacaccacagccctccaggaccctatggtctctcccaggcttgatgtg gcccccacaggcctccagggcccacagggtggcctaaaacctcagggtgcccgctgggtc tgccgcagcttccgccgccacctggaccagtgtgagcaccagattgggccccgggaaatc gagttccagctgctcaacagcgcccaagagcccctcttccactgcaactgcacgcgccgt ctggcacgcttcctgaggctccacagcccacccgaggttaccaacatgctttgggagctg ctgggcacaacctgcttcaagctggcccctccactggactgtgtggaaggcaaaaactgt tccagagaccctagggccatcagggtgtcagcccggcacttgcggaggcttcagcagagg cgacaccagctccaggataaaggcacagatgagaggcagccatggccttcagagcccctg agaggccccatgtcattctacaaccagtgcctgcagctaacccaggcagccaggagaccc gacaggcagcagaagtcctggagccagtga

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