Entry |
|
Symbol |
PLA2G, SPLA2
|
Name |
secretory phospholipase A2 [EC: 3.1.1.4]
|
Pathway |
map00592 | alpha-Linolenic acid metabolism |
map01110 | Biosynthesis of secondary metabolites |
map04270 | Vascular smooth muscle contraction |
|
Reaction |
R01315 | phosphatidylcholine 2-acylhydrolase |
R01317 | phosphatidylcholine 2-acylhydrolase |
R02053 | phosphatidylethanolamine 2-acylhydrolase |
R07064 | phosphatidylcholine 2-acylhydrolase |
R07379 | plasmenylethanolamine 2-acylhydrolase |
R07387 | plasmanylcholine 2-acylhydrolase |
|
Disease |
H02440 | Fleck retina, familial benign |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
K01047 PLA2G, SPLA2; secretory phospholipase A2
00565 Ether lipid metabolism
K01047 PLA2G, SPLA2; secretory phospholipase A2
00590 Arachidonic acid metabolism
K01047 PLA2G, SPLA2; secretory phospholipase A2
00591 Linoleic acid metabolism
K01047 PLA2G, SPLA2; secretory phospholipase A2
00592 alpha-Linolenic acid metabolism
K01047 PLA2G, SPLA2; secretory phospholipase A2
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
K01047 PLA2G, SPLA2; secretory phospholipase A2
09150 Organismal Systems
09153 Circulatory system
04270 Vascular smooth muscle contraction
K01047 PLA2G, SPLA2; secretory phospholipase A2
09154 Digestive system
04972 Pancreatic secretion
K01047 PLA2G, SPLA2; secretory phospholipase A2
04975 Fat digestion and absorption
K01047 PLA2G, SPLA2; secretory phospholipase A2
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins
K01047 PLA2G, SPLA2; secretory phospholipase A2
Enzymes [BR:ko01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
K01047 PLA2G, SPLA2; secretory phospholipase A2
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
Centrosome formation proteins
Centriole proteins
K01047 PLA2G, SPLA2; secretory phospholipase A2
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Other DBs |
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Genes |
» show all
|
Reference |
|
Authors |
Chen J, Engle SJ, Seilhamer JJ, Tischfield JA |
Title |
Cloning and recombinant expression of a novel human low molecular weight Ca(2+)-dependent phospholipase A2. |
Journal |
J Biol Chem 269:2365-8 (1994) |
Sequence |
|
Reference |
|
Authors |
Ishizaki J, Suzuki N, Higashino K, Yokota Y, Ono T, Kawamoto K, Fujii N, Arita H, Hanasaki K |
Title |
Cloning and characterization of novel mouse and human secretory phospholipase A(2)s. |
Journal |
|
Sequence |
|
Reference |
|
Authors |
Suzuki N, Ishizaki J, Yokota Y, Higashino K, Ono T, Ikeda M, Fujii N, Kawamoto K, Hanasaki K |
Title |
Structures, enzymatic properties, and expression of novel human and mouse secretory phospholipase A(2)s. |
Journal |
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Sequence |
|
Reference |
|
Authors |
Burke JE, Dennis EA |
Title |
Phospholipase A2 biochemistry. |
Journal |
|
Reference |
|
Authors |
Farooqui AA, Horrocks LA |
Title |
Brain phospholipases A2: a perspective on the history. |
Journal |
|
Reference |
|
Authors |
Kudo I, Murakami M |
Title |
Phospholipase A2 enzymes. |
Journal |
|
Reference |
|
Authors |
Schaloske RH, Dennis EA |
Title |
The phospholipase A2 superfamily and its group numbering system. |
Journal |
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LinkDB |
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