Homo sapiens (human): 50944
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Entry
50944 CDS
T01001
Symbol
SHANK1, SPANK-1, SSTRIP, synamon
Name
(RefSeq) SH3 and multiple ankyrin repeat domains 1
KO
K15009
SH3 and multiple ankyrin repeat domains protein
Organism
hsa
Homo sapiens (human)
Pathway
hsa04724
Glutamatergic synapse
Network
nt06544
Neuroactive ligand signaling
Element
N01880
GRM1/5-interacting scaffold proteins
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09156 Nervous system
04724 Glutamatergic synapse
50944 (SHANK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ank_2
Ank
SAM_1
Ank_4
Ank_5
SH3_2
SAM_2
PDZ_6
PDZ
SH3_1
SH3_9
FERM_f0
SAM_PNT
Motif
Other DBs
NCBI-GeneID:
50944
NCBI-ProteinID:
NP_057232
OMIM:
604999
HGNC:
15474
Ensembl:
ENSG00000161681
UniProt:
Q9Y566
Structure
PDB
PDBj
LinkDB
All DBs
Position
19:complement(50659255..50719802)
Genome browser
AA seq
2161 aa
AA seq
DB search
MTHSPATSEDEERHSASECPEGGSESDSSPDGPGRGPRGTRGQGSGAPGSLASVRGLQGR
SMSVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLF
QPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGL
KKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHI
DFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELL
LFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKE
TCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARR
RGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTK
LSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGS
LGSRGRRRKLYSAVPGRSFMAVKSYQAQAEGEISLSKGEKIKVLSIGEGGFWEGQVKGRV
GWFPSDCLEEVANRSQESKQESRSDKAKRLFRHYTVGSYDSFDAPSLMDGIGPGSDYIIK
EKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGD
FLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKAPQQAKRLPPP
TISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAAQQTISASESPG
PGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPY
LAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGG
PLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHP
PHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGP
ALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQP
PPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSP
APAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLST
DAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAY
GGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRP
PSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAA
RRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQP
RAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGE
FLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDST
ASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDS
RSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGS
STPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLAL
RACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQA
SALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQ
RQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTST
RHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPT
GGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLSLPPDKPFGAKPLGFWTK
FDVADWLEWLGLAEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRALKFFLE
R
NT seq
6486 nt
NT seq
+upstream
nt +downstream
nt
atgacccacagccccgcgacaagcgaggacgaggaacgccacagtgccagcgagtgtccc
gaggggggctcagagtccgacagctccccagacgggccaggtcgaggcccccgggggacc
cggggccagggcagtggggcacctggtagcctggcctctgttagaggcctccagggccgc
tcaatgtccgtcccagacgacgcccacttcagcatgatggtcttcaggattggcatcccg
gacctgcaccagacaaaatgccttcgcttcaaccccgatgccaccatctggacggccaag
cagcaggtgctctgtgccctgagcgagagcctgcaggatgtgctcaactatggcctgttc
caaccggccacctccggccgcgatgccaacttcctggaggaggagaggctgctgcgggag
tacccccagtcctttgagaagggggtcccctacctggagttccgatacaagacccgagtt
tacaaacagaccaacctggatgagaagcagctggccaagttgcacacgaagacggggttg
aagaagttcctggagtatgtgcagctcgggacatctgacaaggtggcgcggctgctggac
aaggggctggaccccaattaccatgactcggattcgggagagacccccttgacactggcg
gcccagaccgaaggctctgtagaggtgattcgaaccctgtgcctgggcggggcccacatt
gacttccgggcccgggatggcatgaccgcactgcataaggccgcatgcgcccgacactgc
ctggcactcacggcgctcctggaccttgggggttcccccaactacaaggaccgtcggggg
ctgacccctctgttccacacggccatggtgggtggtgacccccgatgctgcgagctgctc
ctgttcaacagggcccagctgggcatagctgatgagaacggctggcaggaaatccaccag
gcctgccagcggggtcactctcagcacctggagcatctgcttttctacggggctgagcct
ggagcccagaacgcctcggggaacacggctctgcacatctgcgccctctacaacaaggag
acctgtgccaggatcctcctgtatcgaggtgccgacaaggatgtgaagaacaacaacgga
cagacccccttccaggtggcagtgattgctgggaattttgagctgggggagctgatccga
aaccaccgagaacaggatgtggtgcccttccaggagtcccccaagtacgcggcccggcga
cgggggcccccaggcacagggctgacggtgcccccggcgctgctgcgggccaacagtgac
accagcatggcgctgcccgactggatggtgttctccgccccgggggccgcgtcctctggg
gcccctggccctacctcagggtcccagggccagtcgcagccctcggcccccaccaccaag
ctcagcagcgggaccctccgaagtgccagcagcccccggggtgccagggcccgctctcca
tcccgagggaggcaccctgaggacgccaagaggcagccccgaggccggcccagctccagc
gggacaccccgggaagggccagccgggggcacggggggctcagggggccccgggggctcc
ctgggcagccgcgggaggcggaggaagctctactcagcggtacccggacgctccttcatg
gctgtgaagtcctaccaggcccaagccgagggggagatctccctgagcaagggcgagaag
atcaaagtacttagcatcggggaaggaggcttctgggaaggccaggtcaaaggtcgtgtt
ggctggttcccctctgactgcctggaagaagtggcgaatcgctctcaggagagcaagcaa
gaaagccgcagtgacaaggcaaagagactcttccggcattataccgtgggctcctacgac
agctttgatgccccaagcttaatggatgggattggcccagggagcgattacatcattaag
gagaagacagtcttgctgcagaagaaggacagtgaggggtttgggttcgtgctccggggg
gccaaggcgcagacccccatcgaggagttcacccccaccccggccttcccggcgctgcag
tacctggagtcggtggacgagggtggcgtggcatggcgagctggactgcgaatgggagac
ttcctcatcgaggtgaacgggcagaatgtggtgaaggtcggccaccgacaggtggtgaac
atgatccgccaagggggcaacacgctgatggtgaaggtggtgatggtcaccaggcacccg
gacatggatgaggcagtgcacaagaaagcaccccagcaggccaagcggctgccgccccca
accatctccctgcgttccaaatctatgacctcagagctggaggagatggagtacgagcag
cagccggcgccggtgcccagcatggagaaaaagcggaccgtgtatcagatggctctcaac
aaactggacgaaatcctggccgcagctcaacagaccatcagtgcaagcgaaagccctggt
cccggtggcctcgcgtccctgggcaaacaccgacccaaaggtttctttgccactgagtcg
agcttcgatccccaccaccgtgcccagccaagttacgagcgtccttctttcctgcctcca
ggacctgggttgatgctccggcaaaaatctatcggtgcggcagaagatgacagaccttac
ctagcacccccagccatgaaattcagccgcagcctgtctgtgcctggttcggaggacatt
cccccgccacccaccacgtccccaccggagcctccctacagcacacctccagtcccctcc
tcctcagggcgcctcaccccctcccctcggggagggcccttcaaccctggctctggtggc
cccctccccgcctcctcccctgcatcctttgacgggccctcccctcccgacactcgcgtg
gggagccgcgagaagagcctgtaccacagtgggcccctgcccccggcccaccaccacccg
ccccaccaccaccaccaccacgccccgccccctcagccccaccaccaccacgcccacccc
cctcatcctcccgagatggagacaggcggctctcccgacgaccctccaccccgcctggct
ctggggccccagcccagcctgcgaggctggaggggcggcgggcccagcccgaccccgggg
gccccgtccccatcgcaccacggcagcgcgggcgggggcggcggctcctcccagggcccg
gctctacgctatttccagctgcccccgcgggcggccagcgcagccatgtacgtgcccgcc
cgctcgggccgcggccgcaagggcccgctggtcaagcagaccaaggtggaaggcgagccc
cagaagggcggcggcctcccgcccgcgccgtcgcccacgtccccggcctccccgcagccg
ccgcccgccgtggccgcgccctcggagaagaactccatccccatccccaccatcatcatc
aaggccccgtccaccagtagcagcggccgcagcagccagggcagcagcaccgaggcggag
ccccccacccagccggagcccacgggaggcggcggcggcggcggctcctcgcccagcccc
gccccggccatgtcacccgtgcccccgtccccctcgcccgtgcccacccccgcctcgccc
agcggcccggccacgctggacttcacgagccagttcggggccgccctggtgggggcggcc
cggagggaggggggctggcagaatgaggcgcgccggcgctccacgctgttcctgtccacc
gacgcgggggacgaggacggcggggacggcgggctgggcacaggggcggccccgggcccg
cggctgcgccactccaaatccatcgacgagggcatgttctccgccgagccctacctccga
ctggagtctgcgggcagcggcgcgggctacggcggctacggggccggtagccgagcctac
gggggtggcgggggcagcagcgccttcaccagcttcctgcccccgcgacccctggtgcac
ccgctgaccggcaaggccctggatcccgcctccccgctggggctggccctggccgcccgc
gagcgagcgctgaaggagtcctcggagggcggcggggccccccagccgcctcccaggccc
ccatcgccccgctacgaggccccgccgcccaccccgcaccaccactcgccccacgcccac
cacgagccagtgctgcgtctctggggggcctccccgccggaccctgcgcgccgggagctg
gggtacagggccgggctgggcagccaggagaagtcccttcccgccagcccgcccgccgcc
cggcgttccctgctacaccgcctgccgcccaccgctcccggggtggggcccctcctgctg
cagctggggacggagcccccggccccgcaccccggagtaagcaagccctggaggtccgca
gcccccgaagaacccgagcggctgccgctgcacgtgcggttccttgaaaactgccagccc
cgggcccctgtgacgagcggaaggggtcccccctcggaggacgggccgggggtcccgccg
cccagcccacgccggtccgtgcccccctccccgacctccccgagggccagcgaagagaac
gggctgcccctgctggtcctgccgcctcccgccccctcggtggatgtggaagatggcgaa
ttccttttcgtggaaccgctgcctccgcctctggaattctccaacagcttcgaaaagcca
gagtcgcccctcacgcctgggcctccccacccgctgcccgacacacctgcccctgccacc
ccgttaccccctgtgccacccccggctgtggccgcagcccctcccaccctggactccacc
gcatccagcctgacatcctatgacagcgaggtggccaccctgacccagggggcctccgcc
gctcctggggacccccatccaccaggcccgcctgccccagcagcaccggctcccgctgcc
ccacagcctggcccggaccctccgcctggcacggattctggcatcgaggaggtggacagt
cggagcagcagtgaccacccactggagaccatcagcagcgcctccacgctgagcagccta
tctgccgaaggtggtggcagcgcagggggtgggggcggggctggggccggtgtggccagt
gggccggagcttctggacacctatgtggcctacctggacggccaggcctttgggggcagc
agtactcccggcccgccataccctcctcagctcatgactccctctaagctccggggccgg
gcgctaggagccagcggaggcctgcggcctggccccagcgggggactccgagaccctgtt
acccccaccagccccaccgtctcggtgacaggggctggaaccgatgggctgctggccctg
cgtgcttgttcaggaccccccacggcaggcgtggcggggggtccggtggctgtagagcca
gaagtcccaccggtgcccttgccgacggcctcctctctgccccggaagctgctgccctgg
gaggagggcccgggcccaccgccaccacctctgcccgggcccttggcccagcctcaggcc
tcagccttggccacagtaaaagccagcatcatcagtgaactcagctccaagcttcagcag
tttgggggctcctcggcagctggcggcgctctgccctgggcccgaggaggcagtggggga
ggcggagacagccaccacgggggagccagctatgtccccgagaggacctcctccctgcag
cggcagagactctccgacgactcccagtcctcactcctctccaagcctgtcagcagcctg
tttcagaactggcccaaaccacctctgccgccactccccaccggaacaggggtctcccct
acagccgctgcggccccaggggccacctcaccctcagcctcctcctcctccacgtccacc
cgccacctccagggcgtggagttcgagatgcggccccctctgctccgccgggcccccagc
ccctcgctgctgcccgcctcggagcacaaggtcagccctgcgcccaggccctcgtccctg
cccatcctgccttccggacccctctacccaggcctctttgacatccgtggctccccaact
ggaggggcaggaggctcggctgaccccttcgccccagtctttgtgccgccacacccgggg
atatccggggggctcgggggagccttgtcaggggcctcgcgctccctctcaccgacccgc
ctgctctcgctgcccccggacaagccgtttggcgctaaacctctggggttctggaccaag
ttcgacgtggctgattggctggagtggctgggtttggcggagcaccgagcccagttcctg
gaccacgagatcgatggctcccacctgcccgccttgaccaaggaggactacgtcgatcta
ggtgtgaccagggtgggccaccgcatgaacatcgaccgggctctcaaattcttcctggag
aggtga
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