Homo sapiens (human): 51366
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Entry
51366 CDS
T01001
Symbol
UBR5, DD5, EDD, EDD1, HYD
Name
(RefSeq) ubiquitin protein ligase E3 component n-recognin 5
KO
K10593
E3 ubiquitin-protein ligase EDD1 [EC:
2.3.2.26
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04120
Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
51366 (UBR5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
51366 (UBR5)
Enzymes [BR:
hsa01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
51366 (UBR5)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
HECT type E3
51366 (UBR5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
E3_UbLigase_EDD
PABP
zf-UBR
Motif
Other DBs
NCBI-GeneID:
51366
NCBI-ProteinID:
NP_056986
OMIM:
608413
HGNC:
16806
Ensembl:
ENSG00000104517
Pharos:
O95071
(Tbio)
UniProt:
O95071
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:complement(102252273..102412700)
Genome browser
AA seq
2799 aa
AA seq
DB search
MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
KESKFRREMEKLRNQQSRDLSLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVT
FKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDRER
EREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALGER
LYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADS
ILDLGLVDSSEKVQQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGK
NTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLR
QLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAE
HRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDES
GENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQ
HLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
NT seq
8400 nt
NT seq
+upstream
nt +downstream
nt
atgacgtccatccatttcgtggttcacccgctgccgggcaccgaggaccagctcaatgac
aggttacgagaagtttctgagaagctgaacaaatataatttaaacagccacccccctttg
aatgtattggaacaggctactattaaacagtgtgtggtgggaccaaatcatgctgccttt
cttcttgaggatggtagagtttgcaggattggtttttcagtacagccagacagattggaa
ttgggtaaacctgataataatgatgggtcaaagttgaacagcaactcgggggcagggagg
acgtcaaggcctggtaggacaagcgactctccatggtttctctcaggttctgagactcta
ggcaggctggcaggcaacaccttaggaagccgctggagttctggagtgggtggaagtggt
ggaggatcctctggtaggtcatcagctggagctcgagattcccgccggcagactcgagtt
attcggacaggacgggatcgagggtctgggcttttgggcagtcagccccagccagttatt
ccagcatctgtcattccagaggagctgatttcacaggcccaagttgttttacaaggcaaa
tccagaagtgtcattattcgagaacttcagagaacaaatcttgatgtgaaccttgctgta
aataatttacttagccgggatgatgaagatggagatgatggggatgatacagccagcgaa
tcttatttgcctggagaggatcttatgtctctccttgatgccgacattcattctgcccac
ccaagtgtcattattgatgcagatgccatgttttctgaagacattagctattttggttac
ccttcttttcgtcgttcatcactttccaggctaggctcatctcgagttctccttcttccc
ttagagagagactctgagctgttgcgtgaacgtgaatccgttttacgtttacgtgaacga
aggtggcttgatggagcctcatttgataatgaaaggggttctaccagcaaggaaggagag
ccaaacttggataagaagaatacacctgttcaaagtccagtatctctaggagaagatttg
cagtggtggcctgataaggatggaacaaaattcatctgtattggggctctgtattctgaa
cttctggctgtcagcagtaaaggagaactttatcagtggaaatggagtgaatctgagcct
tacagaaatgcccagaatccttcattacatcatccacgagcaacatttttggggttaacc
aatgaaaagatagtcctcctgtctgcaaatagcataagagcaactgtagctacagaaaat
aacaaggttgctacatgggtggatgaaactttaagttctgtggcttctaaattagagcac
actgctcagacttactctgaacttcaaggagagcggatagtttctttacattgctgtgcc
ctttacacctgcgctcagctggaaaacagtttatattggtggggtgtagttccttttagt
caaaggaagaaaatgttagagaaagctagagcaaaaaataaaaagcctaaatccagtgct
ggtatttcttcaatgccgaacatcactgttggtacccaggtatgcttgagaaataatcct
ctttatcatgctggagcagttgcattttcaattagtgctgggattcctaaagttggtgtc
ttaatggagtcagtttggaatatgaatgacagctgtagatttcaacttagatctcctgaa
agcttgaaaaacatggaaaaagctagcaaaactactgaagctaagcctgaaagtaagcag
gagccagtgaaaacagaaatgggtcctccaccatctccagcatccacgtgtagtgatgca
tcctcaattgccagcagtgcatcaatgccatacaaacgacgacggtcaacccctgcacca
aaagaagaggaaaaggtgaatgaagagcagtggtctcttcgggaagtggtttttgtggaa
gatgtcaagaatgttcctgttggcaaggtgctaaaagtagatggtgcctatgttgctgta
aaatttccaggaacctccagtaatactaactgtcagaacagctctggtccagatgctgac
ccttcttctctcctgcaggattgtaggttacttagaattgatgaattgcaggttgtcaaa
actggtggaacaccgaaggttcccgactgtttccaaaggactcctaaaaagctttgtata
cctgaaaaaacagaaatattagcagtgaatgtagattccaaaggtgttcatgctgttctg
aagactggaaattgggtacgatactgtatctttgatcttgctacaggaaaagcagaacag
gaaaataattttcctacaagcagcattgctttccttggtcagaatgagaggaatgtagcc
attttcactgctggacaggaatctcccattattcttcgagatggaaatggtaccatctac
ccaatggccaaagattgcatgggaggaataagggatcccgattggctggatcttccacct
attagtagtcttggaatgggtgtgcattctttaataaatcttcctgccaattcaacaatc
aaaaagaaagctgctgttatcatcatggctgtagagaaacaaaccttaatgcaacacatt
ctgcgctgtgactatgaggcctgtcgacaatatctaatgaatcttgagcaagcggttgtt
ttagagcagaatctacagatgctgcagacattcatcagccacagatgtgatggaaatcga
aatattttgcatgcttgtgtatcagtttgctttccaaccagcaataaagaaactaaagaa
gaagaggaagcggagcgttctgaaagaaatacatttgcagaaaggctttctgctgttgag
gccattgcaaatgcaatatcagttgtttcaagtaatggcccaggtaatcgggctggatca
tcaagtagccgaagtttgagattacgggaaatgatgagacgttcgttgagagcagctggt
ttgggtagacatgaagctggagcttcatccagtgaccaccaggatccagtttcacccccc
atagctccccctagttgggttcctgaccctcctgcgatggatcctgatggtgacattgat
tttatcctggcccccgctgtgggatctcttaccacagcagcaaccggtactggtcaagga
ccaagcacctccactattccaggtccttccacagagccatctgtagtagaatccaaggat
cgaaaggcgaatgctcattttatattgaaattgttatgtgacagtgtggttctccagccc
tatctacgagaacttctttctgccaaggatgcaagagggatgaccccatttatgtcagct
gtaagtggccgagcttatcctgctgcaattaccatcttagaaactgctcagaaaattgca
aaagctgaaatatcctcaagtgaaaaagaggaagatgtattcatgggaatggtttgccca
tcaggtaccaaccctgatgactctcctttatatgttttatgttgtaatgacacttgcagt
tttacatggactggagcagagcacattaaccaggatatttttgagtgtcgaacttgtggc
ttgctggagtcactgtgttgttgtacggaatgtgcaagggtttgtcataaaggtcatgat
tgcaaactcaaacggacatcaccaacagcctactgtgattgttgggagaaatgtaaatgt
aaaactcttattgctggacagaaatctgctcgtcttgatctactttatcgcctgctcact
gctactaatctggttactctgccaaacagcaggggagagcacctcttactattcttagta
cagacagtcgcaaggcagacggtggagcattgtcaatacaggccacctcgaatcagggaa
gatcgtaaccgaaaaacagccagtcctgaagattcagatatgccagatcatgatttagag
cctccaagatttgcccagcttgcattggagcgtgttctacaggactggaatgccttgaaa
tctatgattatgtttgggtcgcaggagaataaagaccctcttagtgccagcagtagaata
ggccatcttttgccagaagagcaagtatacctcaatcagcaaagtggcacaattcggctg
gactgtttcactcattgccttatagttaagtgtacagcagatattttgcttttagatact
ctactaggtacactagtgaaagaactccaaaacaaatatacacctggacgtagagaagaa
gctattgctgtgacaatgaggtttctacgttcagtggcaagagtttttgttattctgagt
gtggaaatggcttcatccaaaaagaaaaacaactttattccacagccaattggaaaatgc
aagcgtgtattccaagcattgctaccttacgctgtggaagaattgtgcaacgtagcagag
tcactgattgttcctgtcagaatggggattgctcgtccaactgcaccatttaccctggct
agtactagcatagatgccatgcagggcagtgaagaattattttcagtggaaccactacca
ccacgaccatcatctgatcagtctagcagctccagtcagtctcagtcatcctacatcatc
aggaatccacagcagaggcgcatcagccagtcacagcccgttcggggcagagatgaagaa
caggatgatattgtttcagcagatgtggaagaggttgaggtggtggagggtgtggctgga
gaagaggatcatcatgatgaacaggaagaacacggggaagaaaatgctgaggcagaggga
caacatgatgagcatgatgaagacgggagtgatatggagctggacttgttagcagcagct
gaaacagaaagtgatagtgaaagtaaccacagcaaccaagataatgctagtgggcgcaga
agcgttgtcactgcagcaactgctggttcagaagcaggagcaagcagtgttcctgccttc
ttttctgaagatgattctcaatcgaatgactcaagtgattctgatagcagtagtagtcag
agtgacgacatagaacaggagacctttatgcttgatgagccattagaaagaaccacaaat
agctcccatgccaatggtgctgcccaagctccccgttcaatgcagtgggctgtccgcaac
acccagcatcagcgagcagccagtacagccccttccagtacatctacaccagcagcaagt
tcagcgggtttgatttatattgatccttcaaacttacgccggagtggtaccatcagtaca
agtgctgcagctgcagcagctgctttggaagctagcaacgccagcagttacctaacatct
gcaagcagtttagccagggcttacagcattgtcattagacaaatctcggacttgatgggc
cttattcctaagtataatcacctagtatactctcagattccagcagctgtgaaattgact
taccaagatgcagtaaacttacagaactatgtagaagaaaagcttattcccacttggaac
tggatggtcagtattatggattctactgaagctcaattacgttatggttctgcattagca
tctgctggtgatcctggacatccaaatcatcctcttcacgcttctcagaattcagcgaga
agagagaggatgactgcgcgagaagaagctagcttacgaacacttgaaggcagacgacgt
gccaccttgcttagcgcccgtcaaggaatgatgtctgcacgaggagacttcctaaattat
gctctgtctctaatgcggtctcataatgatgagcattctgatgttcttccagttttggat
gtttgctcattgaagcatgtggcatatgtttttcaagcacttatatactggattaaggca
atgaatcagcagacaacattggatacacctcaactagaacgcaaaaggacgcgagaactc
ttggaactgggtattgataatgaagattcagaacatgaaaatgatgatgacaccaatcaa
agtgctactttgaatgataaggatgatgactctcttcctgcagaaactggccaaaaccat
ccatttttccgacgttcagactccatgacattccttgggtgtatacccccaaatccattt
gaagtgcctctggctgaagccatccccttggctgatcagccacatctgttgcagccaaat
gctagaaaggaggatctttttggccgtccaagtcagggtctttattcttcatctgccagt
agtgggaaatgtttaatggaggttacagtggatagaaactgcctagaggttcttccaaca
aaaatgtcttatgctgccaatctgaaaaatgtaatgaacatgcaaaaccggcaaaaaaaa
gaaggggaagaacagcccgtgctgccagaagaaactgagagttcaaaaccagggccatct
gctcatgatcttgctgcacaattaaaaagtagcttactagcagaaataggacttactgaa
agtgaagggccacctctcacatctttcaggccacagtgtagctttatgggaatggttatt
tcccatgatatgctgctaggacgttggcgcctttctttagaactgttcggcagggtattc
atggaagatgttggagcagaacctggatcaatcctaactgaattgggtggttttgaggta
aaagaatcaaaattccgcagagaaatggaaaaactgagaaaccagcagtcaagagatttg
tcactagaggttgatcgggatcgagatcttctcattcagcagactatgaggcagcttaac
aatcactttggtcgaagatgtgctactacaccaatggctgtacacagagtaaaagtcaca
tttaaggatgagccaggagagggcagtggtgtagcacgaagtttttatacagccattgca
caagcatttttatcaaatgaaaaattgccaaatctagagtgtatccaaaatgccaacaaa
ggcacccacacaagtttaatgcagagattaaggaaccgaggagagagagaccgggaaagg
gagagagaaagggaaatgaggaggagtagtggtttgcgagcaggttctcggagggaccgg
gatagagactttagaagacagctttccatcgacactaggccctttagaccagcctctgaa
gggaatcctagcgatgatcctgagcctttgccagcacatcggcaggcacttggagagagg
ctttatcctcgtgtacaagcaatgcaaccagcatttgcaagtaaaatcactggcatgttg
ttggaattatccccagctcagctgcttctccttctagcaagtgaggattctctgagagca
agagtggatgaggccatggaactcattattgcacatggacgggaaaatggagctgatagt
atcctggatcttggattagtagactcctcagaaaaggtacagcaggaaaaccgaaagcgc
catggctctagtcgaagtgtagtagatatggatttagatgatacagatgatggtgatgac
aatgcccctttgttttaccaacctgggaaaagaggattttatactccaaggcctggcaag
aacacagaagcaaggttgaattgtttcagaaacattggcaggattcttggactatgtctg
ttacagaatgaactatgtcctatcacattgaatagacatgtaattaaagtattgcttggt
agaaaagtcaattggcatgattttgctttttttgatcctgtaatgtatgagagtttgcgg
caactaatcctcgcgtctcagagttcagatgctgatgctgttttctcagcaatggatttg
gcatttgcaattgacctgtgtaaagaagaaggtggaggacaggttgaactcattcctaat
ggtgtaaatataccagtcactccacagaatgtatatgagtatgtgcggaaatacgcagaa
cacagaatgttggtagttgcagaacagcccttacatgcaatgaggaaaggtctactagat
gtgcttccaaaaaattcattagaagatttaacggcagaagattttaggcttttggtaaat
ggctgcggtgaagtcaatgtgcaaatgctgatcagttttacctctttcaatgatgaatca
ggagaaaatgctgagaagcttctgcagttcaagcgttggttctggtcaatagtagagaag
atgagcatgacagaacgacaagatcttgtttacttttggacatcaagcccatcactgcca
gccagtgaagaaggattccagcctatgccctcaatcacaataagaccaccagatgaccaa
catcttcctactgcaaatacttgcatttctcgactttacgtcccactctattcctctaaa
cagattctcaaacagaaattgttactcgccattaagaccaagaattttggttttgtgtag
DBGET
integrated database retrieval system
