Homo sapiens (human): 5145 Help Entry 5145              CDS       T01001                                  Symbol PDE6A, CGPR-A, PDEA, RP43 Name (RefSeq) phosphodiesterase 6A   KO K08718   rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [EC:3.1.4.35] Organism hsa  Homo sapiens (human) Pathway hsa00230   Purine metabolism hsa01100   Metabolic pathways hsa04744   Phototransduction Disease H00527   Retinitis pigmentosa Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     5145 (PDE6A) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.35  3',5'-cyclic-GMP phosphodiesterase      5145 (PDE6A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PDEase_I GAF GAF_2 LON_substr_bdg HD-CE Motif Other DBs NCBI-GeneID:  5145 NCBI-ProteinID:  NP_000431 OMIM:  180071 HGNC:  8785 Ensembl:  ENSG00000132915 UniProt:  P16499 LinkDB All DBs Position 5:complement(149857953..149944793) Genome browser AA seq 860 aa AA seqDB search MGEVTAEEVEKFLDSNIGFAKQYYNLHYRAKLISDLLGAKEAAVDFSNYHSPSSMEESEI IFDLLRDFQENLQTEKCIFNVMKKLCFLLQADRMSLFMYRTRNGIAELATRLFNVHKDAV LEDCLVMPDQEIVFPLDMGIVGHVAHSKKIANVPNTEEDEHFCDFVDILTEYKTKNILAS PIMNGKDVVAIIMAVNKVDGSHFTKRDEEILLKYLNFANLIMKVYHLSYLHNCETRRGQI LLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEVP PYSGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPAYVAQNGLICNIM NAPAEDFFAFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLM ESLTQFLGWSVLNPDTYESMNKLENRKDIFQDIVKYHVKCDNEEIQKILKTREVYGKEPW ECEEEELAEILQAELPDADKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQE ALVRFMYSLSKGYRKITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHD IDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIH MMDIAIIATDLALYFKKRTMFQKIVDQSKTYESEQEWTQYMMLEQTRKEIVMAMMMTACD LSAITKPWEVQSQVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFV CTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYDAKMKVQEEKKQKQQSAKSAAAGN QPGGNPSPGGATTSKSCCIQ NT seq 2583 nt NT seq  +upstreamnt  +downstreamnt atgggcgaggtgacagcagaggaggtggagaagttcctggactcgaatattggctttgcc aaacagtactacaacctccactaccgggccaagctcatctccgacctccttggggccaag gaggctgccgtggacttcagcaactaccactccccgagcagcatggaggagagcgaaatc atctttgatctcctgcgggactttcaggagaatttacagacagagaaatgcatcttcaat gtcatgaagaagctgtgcttcctcctgcaggcagaccgcatgagcctgttcatgtaccgg acccgcaatggcatcgcagagctggccaccaggcttttcaatgtccacaaggatgctgtc ctcgaggactgcctggtgatgcccgaccaagagatcgtcttccctttggacatgggcatc gtgggccatgtcgcacactctaagaagattgctaacgtccccaacacagaggaggatgag catttctgtgactttgtggacatcctcacagagtacaagaccaagaacatcttggcttcc cccataatgaatgggaaggatgtggtggccataatcatggctgtgaataaagtggatgga tcccacttcaccaagagagatgaagagattcttctcaagtacctcaattttgcaaatcta atcatgaaggtgtaccacctgagttacctgcacaactgtgaaactcgacgtggccagata ctgctgtggtctgggagcaaagtctttgaagaacttacggacatcgaacgacagttccac aaagccctgtacacagtccgtgctttcctcaactgtgacagatactctgtgggtctctta gacatgaccaagcagaaggaattttttgatgtgtggccggttctgatgggtgaagttcca ccttactctggtcccaggactccggatggaagagaaattaacttttacaaggtcattgac tacatcctgcatggcaaagaggacatcaaagtcatcccgaatccacctcctgaccattgg gctttagtaagcggtctcccagcttatgttgcccagaatggcctgatttgcaacatcatg aatgcgcctgcggaggacttttttgcatttcagaaagaacctctggatgagtctggatgg atgattaaaaatgtgctttcaatgccgattgtgaacaagaaggaagaaattgttggagtg gccacattttacaatcgtaaagatgggaagccctttgatgaaatggatgagacgctcatg gagtctttgactcaatttctgggctggtctgtcttaaatcctgacacctatgagtcaatg aataaacttgaaaataggaaggatattttccaggacatagtaaaatatcatgtgaagtgt gacaatgaagaaattcagaaaatcttgaaaaccagagaggtgtatgggaaggagccatgg gagtgtgaggaagaggagctggctgagatcctgcaagcggagctgccagatgcagataaa tacgaaattaataaatttcacttcagtgacttacccctaacagaactggagctggtaaaa tgtggaatacagatgtattatgagctcaaagtggtggataaatttcacattccacaagag gccctggtgcggttcatgtactccctgagtaagggctaccgcaagatcacctaccacaac tggcggcacggcttcaacgtggggcagaccatgttctccctgctggtgacgggaaagctg aagcgctacttcacggacctagaggccttggccatggtcactgctgctttctgccatgac attgaccacagaggcaccaataacctctaccagatgaaatcccagaacccactggccaag ctccatgggtcctctatcttggaaagacaccacttggagtttggcaaaacactgctcaga gacgagagcctgaatatctttcaaaacctcaatcgtcgacagcatgagcatgccatccac atgatggacattgcaatcattgccacagacctcgccctgtatttcaagaagaggacgatg ttccaaaagatcgtggatcagtctaagacatatgagagtgaacaggagtggacacagtac atgatgctggagcagacacggaaggaaatcgttatggccatgatgatgaccgcctgtgat ctctcagccatcaccaaaccctgggaggtgcagagccaggtagctctgctggtggctgct gaattctgggaacaaggtgacctggagcgcacggtgctgcaacagaatcccattcccatg atggacagaaacaaagcagatgaactccctaagcttcaagtcggcttcattgactttgtt tgcaccttcgtctacaaggaattctcccgtttccacgaggagatcaccccaatgttggac gggatcaccaacaatcgcaaggagtggaaggcgcttgctgatgagtacgatgccaagatg aaggtgcaggaggagaagaagcagaaacagcagtcggccaagtcagcagccgcaggaaat cagccggggggaaaccccagcccagggggtgcaactacatccaagtcctgctgcatccag taa

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