Homo sapiens (human): 53358 Help Entry 53358             CDS       T01001                                  Symbol SHC3, N-Shc, NSHC, RAI, SHCC Name (RefSeq) SHC adaptor protein 3   KO K17448   SHC-transforming protein 3 Organism hsa  Homo sapiens (human) Pathway hsa01521   EGFR tyrosine kinase inhibitor resistance hsa01522   Endocrine resistance hsa04012   ErbB signaling pathway hsa04014   Ras signaling pathway hsa04062   Chemokine signaling pathway hsa04072   Phospholipase D signaling pathway hsa04510   Focal adhesion hsa04650   Natural killer cell mediated cytotoxicity hsa04722   Neurotrophin signaling pathway hsa04910   Insulin signaling pathway hsa04915   Estrogen signaling pathway hsa04917   Prolactin signaling pathway hsa04926   Relaxin signaling pathway hsa04935   Growth hormone synthesis, secretion and action hsa05034   Alcoholism hsa05100   Bacterial invasion of epithelial cells hsa05214   Glioma hsa05220   Chronic myeloid leukemia hsa05224   Breast cancer hsa05225   Hepatocellular carcinoma hsa05226   Gastric cancer Network nt06526  MAPK signaling   Element N01595   Regulation of GF-RTK-RAS-ERK signaling pathway, adaptor proteins Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     53358 (SHC3)    04072 Phospholipase D signaling pathway     53358 (SHC3)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     53358 (SHC3)    04062 Chemokine signaling pathway     53358 (SHC3)   09152 Endocrine system    04915 Estrogen signaling pathway     53358 (SHC3)    04917 Prolactin signaling pathway     53358 (SHC3)    04926 Relaxin signaling pathway     53358 (SHC3)    04935 Growth hormone synthesis, secretion and action     53358 (SHC3)   09156 Nervous system    04722 Neurotrophin signaling pathway     53358 (SHC3)  09160 Human Diseases   09162 Cancer: specific types    05225 Hepatocellular carcinoma     53358 (SHC3)    05226 Gastric cancer     53358 (SHC3)    05214 Glioma     53358 (SHC3)    05220 Chronic myeloid leukemia     53358 (SHC3)    05224 Breast cancer     53358 (SHC3)   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     53358 (SHC3)   09165 Substance dependence    05034 Alcoholism     53358 (SHC3)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     53358 (SHC3)    01522 Endocrine resistance     53358 (SHC3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PID SH2 DUF7145 Motif Other DBs NCBI-GeneID:  53358 NCBI-ProteinID:  NP_058544 OMIM:  605263 HGNC:  18181 Ensembl:  ENSG00000148082 UniProt:  Q92529 LinkDB All DBs Position 9:complement(89005771..89178818) Genome browser AA seq 594 aa AA seqDB search MLPRTKYNRFRNDSVTSVDDLLHSLSVSGGGGKVSAARATPAAAPYLVSGEALRKAPDDG PGSLGHLLHKVSHLKLSSSGLRGLSSAARERAGARLSGSCSAPSLAAPDGSAPSAPRAPA MSAARKGRPGDEPLPRPPRGAPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQI TREAISRVCEAVPGAKGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPD SKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGSIGQA FELRFKQYLQCPTKIPALHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKMPPPGGFLDTRL KPRPHAPDTAQFAGKEQTYYQGRHLGDTFGEDWQQTPLRQGSSDIYSTPEGKLHVAPTGE APTYVNTQQIPPQAWPAAVSSAESSPRKDLFDMKPFEDALKNQPLGPVLSKAASVECISP VSPRAPDAKMLEELQAETWYQGEMSRKEAEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQ AKHLLLVDPEGTIRTKDRVFDSISHLINHHLESSLPIVSAGSELCLQQPVERKQ NT seq 1785 nt NT seq  +upstreamnt  +downstreamnt atgcttccacgcaccaagtataaccgcttcaggaatgactcggtgacatcggtcgatgac cttctccacagcctgtcggtgagcggcggcggaggcaaggtttcggcggcgcgcgcgacc ccggcggcggctccctacttggtgtccggcgaggcgctgcgcaaggcgcccgacgatggg cccggcagcctgggccacctgctccacaaggtgtcccacctgaaactctccagctcgggc ctccgcggcctgtcgtcggccgcccgggagcgggcgggcgcgcggctctcgggcagctgc agcgcgcccagcctggccgccccggacggcagtgcgccctcggcgccccgcgccccggcc atgagcgccgccaggaagggccggcccggcgacgagccgctgcccaggccccctcggggg gcgccgcacgccagcgaccaggtgctggggcccggagtcacctacgtggtcaagtacttg gggtgcattgaagttctgcgctcaatgaggtctcttgacttcagtacaagaacacaaatt accagggaagccatcagccgcgtctgtgaagctgtgcctggtgcgaagggagccttcaag aagagaaagcctccaagcaaaatgctgtccagcatcttgggaaagagcaacctccagttt gcgggaatgagcatctctctgaccatctccacggccagtctgaacctgcgaactccggac tccaaacagatcatagcgaatcaccacatgcggtccatctccttcgcctctgggggagac ccggacacaactgactatgttgcatatgtggctaaggaccctgttaatcgcagagcttgt cacattttggaatgctgtgatgggctggcccaggatgtcatcggctccatcggacaagcc tttgagctccggtttaagcaatatttacagtgtcctaccaagattcccgctctccatgat cgaatgcagagtctggatgagccatggacggaagaggagggagatggctcagaccaccca tactacaacagcatcccaagcaagatgcctcctccagggggctttcttgatactagactg aaacccagaccccatgctcctgacacagcccagtttgcaggaaaagagcagacttattac cagggaagacacttaggagacacttttggcgaagactggcagcaaacacctttaaggcaa gggtcctcggacatctacagcacgccagaagggaaactgcacgtggcccccacgggagaa gcacccacctacgtcaacactcagcagatcccaccacaggcctggccggctgcggtcagc agtgctgagagcagcccaaggaaagacctctttgacatgaaaccttttgaagatgctctc aagaaccagcccttggggcccgtgttaagcaaggcagcctccgtggagtgcatcagccct gtgtcacctagagccccagatgccaagatgctggaggaactgcaagccgagacttggtac caaggagagatgagcaggaaggaggcagaggggctgctggagaaagacggagacttcctg gtcaggaagagcaccaccaacccgggctcctttgtcctcacgggcatgcacaatggccag gccaagcacctgctgctcgtggacccagaaggcacgatccggacaaaggacagagtcttt gacagtatcagccacctcatcaaccaccacctagaaagcagcctgcccattgtctctgca gggagtgagctgtgtctccagcagccagtggagaggaagcagtga

DBGET integrated database retrieval system