Homo sapiens (human): 53373
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Entry
53373 CDS
T01001
Symbol
TPCN1, TPC1
Name
(RefSeq) two pore segment channel 1
KO
K16896
two pore calcium channel protein 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04020
Calcium signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
53373 (TPCN1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
53373 (TPCN1)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Calcium channel, two-pore (TPC)
53373 (TPCN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Pilin_N
Motif
Other DBs
NCBI-GeneID:
53373
NCBI-ProteinID:
NP_060371
OMIM:
609666
HGNC:
18182
Ensembl:
ENSG00000186815
UniProt:
Q9ULQ1
B3KSG7
LinkDB
All DBs
Position
12:113221464..113298585
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AA seq
816 aa
AA seq
DB search
MAVSLDDDVPLILTLDEGGSAPLAPSNGLGQEELPSKNGGSYAIHDSQAPSLSSGGESSP
SSPAHNWEMNYQEAAIYLQEGENNDKFFTHPKDAKALAAYLFAHNHLFYLMELATALLLL
LLSLCEAPAVPALRLGIYVHATLELFALMVVVFELCMKLRWLGLHTFIRHKRTMVKTSVL
VVQFVEAIVVLVRQMSHVRVTRALRCIFLVDCRYCGGVRRNLRQIFQSLPPFMDILLLLL
FFMIIFAILGFYLFSPNPSDPYFSTLENSIVSLFVLLTTANFPDVMMPSYSRNPWSCVFF
IVYLSIELYFIMNLLLAVVFDTFNDIEKRKFKSLLLHKRTAIQHAYRLLISQRRPAGISY
RQFEGLMRFYKPRMSARERYLTFKALNQNNTPLLSLKDFYDIYEVAALKWKAKKNREHWF
DELPRTALLIFKGINILVKSKAFQYFMYLVVAVNGVWILVETFMLKGGNFFSKHVPWSYL
VFLTIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIVVLRP
LQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNT
STVADAYRWRNHTVGNRTVVEEGYYYLNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQT
SHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEISKEEL
VAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEW
YEEHAREQEQQRQLSSSAAPAAQQPPGSRQRSQTVT
NT seq
2451 nt
NT seq
+upstream
nt +downstream
nt
atggctgtgagtttggatgacgacgtgccgctcatcctgaccttggatgagggtggcagt
gccccactggctccctccaacggcctgggccaagaagagctacctagcaaaaatggcggc
agctatgccatccacgactcccaggcccccagtctcagctctgggggtgagagttccccc
tccagccccgcacacaactgggagatgaattaccaagaggcagcaatctacctccaggaa
ggcgagaacaacgacaagttcttcacccaccccaaggatgccaaggcgctggcggcctac
ctctttgcacacaatcacctcttctacctgatggagctggccacggccctgctgctgctg
ctgctctccctgtgcgaggcccccgccgtccccgcactccggcttggcatctatgtccac
gccaccctggagctgtttgccctgatggtggtagtgtttgaactctgcatgaagttacgc
tggctgggcctccacaccttcatccggcacaagcggaccatggtcaagacctcggtgctg
gtggtgcagtttgtcgaggccatcgtggtgttggtacggcagatgtcccatgtgcgggtg
acccgagcactgcgctgcattttcctggtggactgtcggtattgcggtggcgtccggcgc
aacctgcggcagatcttccagtccctgccgcccttcatggacatcctcctgctgctgctg
ttcttcatgatcatctttgccatcctcggtttctacttgttctcccctaacccttcagac
ccctacttcagcaccctggagaacagcatcgtcagtctgtttgtccttctgaccacagcc
aatttcccagatgtgatgatgccctcctactcccggaacccctggtcctgcgtcttcttc
atcgtgtacctctccatcgagctgtatttcatcatgaacctgcttctggctgtggtgttc
gacaccttcaatgacattgagaaacgcaagttcaagtctttgctactgcacaagcgaacc
gctatccagcatgcctaccgcctgctcatcagccagaggaggcctgccggcatctcctac
aggcagtttgaaggcctcatgcgcttctacaagccccggatgagtgccagggagcgctat
cttaccttcaaggccctgaatcagaacaacacacccctgctcagcctaaaggacttttac
gatatctacgaagttgctgctttgaagtggaaggccaagaaaaacagagagcactggttt
gatgagcttcccaggacggcgctcctcatcttcaaaggtattaatatccttgtgaagtcc
aaggccttccagtatttcatgtacttggtggtggcagtcaacggggtctggatcctcgtg
gagacatttatgctgaaaggtgggaacttcttctccaagcacgtgccctggagttacctc
gtctttctaactatctatggggtggagctgttcctgaaggttgccggcctgggccctgtg
gagtacttgtcttccggatggaacttgtttgacttctccgtgacagtgttcgccttcctg
ggactgctggcgctggccctcaacatggagcccttctatttcatcgtggtcctgcgcccc
ctccagctgctgaggttgtttaagttgaaggagcgctaccgcaacgtgctggacaccatg
ttcgagctgctgccccggatggccagcctgggcctcaccctgctcatcttttactactcc
ttcgccatcgtgggcatggagttcttctgcgggatcgtcttccccaactgctgcaacacg
agtacagtggcagatgcctaccgctggcgcaaccacaccgtgggcaacaggaccgtggtg
gaggaaggctactattatctcaataattttgacaacatcctcaacagctttgtgaccctg
tttgagctcacagttgtcaacaactggtacatcatcatggaaggcgtcacctctcagacc
tcccactggagccgcctctacttcatgaccttttacattgtgaccatggtggtgatgacg
atcattgtcgcctttatcctcgaggccttcgtcttccgaatgaactacagccgcaagaac
caggactcggaagttgatggtggcatcacccttgagaaggaaatctccaaagaagagctg
gttgccgtcctggagctctaccgggaggcacggggggcctcctcggatgtcaccaggctg
ctggagaccctctcccagatggagagataccagcaacattccatggtgtttctgggacgg
cgatcaaggaccaagagcgacctgagcctgaagatgtaccaggaggagatccaggagtgg
tatgaggagcatgccagggagcaagagcagcagcgacaactcagcagcagtgcagccccc
gccgcccagcagcccccaggcagccgccagcgctcccagaccgttacctag
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