KEGG   Homo sapiens (human): 5356
Entry
5356              CDS       T01001                                 
Symbol
PLRG1, Cwc1, PRL1, PRP46, PRPF46, TANGO4
Name
(RefSeq) pleiotropic regulator 1
  KO
K12862  pleiotropic regulator 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    5356 (PLRG1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    5356 (PLRG1)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5356 (PLRG1)
Spliceosome [BR:hsa03041]
 Complex B
  Other components
   Prp19 complex
    5356 (PLRG1)
 Complex C
   Prp19-CDC5 complex
    5356 (PLRG1)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  Other factors with a suspected DNA repair function
   PSO4 complex
    5356 (PLRG1)
SSDB
Motif
Pfam: WD40 WD40_Prp19 WD40_WDHD1_1st WD40_CDC20-Fz EIF3I WDR55 Beta-prop_EML_2 Beta-prop_TEP1_2nd Beta-prop_CAF1B_HIR1 Beta-prop_WDR90_POC16_2nd Beta-prop_WDR75_1st WD40_MABP1-WDR62_2nd Beta-prop_TEP1_C Beta-prop_SCAP Beta-prop_EML NBCH_WD40 Beta-prop_SPT8 Beta-prop_EIPR1 Beta-prop_DCAF4 WD40_RFWD3 WD40_MABP1-WDR62_1st Beta-prop_NWD2_C WDR90_beta-prop_4th Beta-prop_IFT122_1st Beta-prop_IFT140_1st ANAPC4_WD40 Beta-prop_DCAF12 WDR54 KNTC1_N Beta-prop_WDR19_1st VPS8_N Beta-prop_WDR11_2nd WD40_like
Other DBs
NCBI-GeneID: 5356
NCBI-ProteinID: NP_002660
OMIM: 605961
HGNC: 9089
Ensembl: ENSG00000171566
UniProt: O43660
Structure
LinkDB
Position
4:complement(154535005..154550400)
AA seq 514 aa
MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
SKENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSE
SAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAK
KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL
SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI
DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV
AGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLT
VNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTA
EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
NT seq 1545 nt   +upstreamnt  +downstreamnt
atggtcgaggaggtacagaaacattctgtacacacccttgtgttcaggtcgttgaagagg
acccatgacatgtttgtagctgataatggaaaacctgtgcctttagatgaagagagtcac
aaacgaaaaatggcaatcaagcttcgtaatgagtatggtcctgtgttgcatatgcctact
tcaaaagaaaatcttaaagagaagggtcctcagaatgcaacggattcatatgttcataaa
cagtaccctgccaatcaaggacaagaagttgaatactttgtggcaggtacacatccatac
ccaccaggacctggggttgctttgacagcagatactaagatccagagaatgccaagtgaa
tcagctgcacagtccttagcggtggcattacctttgcagaccaaggctgatgcaaatcgt
actgcccctagtggaagtgaataccgacatcctggggcttctgaccgtccacagcctaca
gcgatgaattcaattgtcatggagactggcaataccaagaactctgcactgatggctaaa
aaagcccctacaatgccaaaaccccagtggcacccaccgtggaaactctacagggttatc
agtgggcatcttggctgggttcgatgtattgctgtggaacctggaaatcagtggtttgtt
actggatctgctgacagaactataaagatctgggacttggctagtggcaaattaaaactg
tcattgactgggcatattagtactgtgcggggcgtgatagtaagcacaaggagcccatat
ctgttctcttgtggagaagacaaacaagtgaaatgctgggatctcgaatacaataaggtt
atacggcattatcatggacatttaagtgcagtgtatggtttggatttgcacccgacaatc
gatgtgttggtaacctgtagtcgagattcaactgcacggatttgggatgtgagaactaaa
gccagtgtacacacattatctggacatacaaatgcagttgctacagtgagatgtcaggct
gcagaaccacaaattattacaggaagccatgatactacaattcgattatgggatctggtg
gctggaaaaacaagagtgacattaacaaatcacaaaaaatcagttagggctgtggtttta
catccaagacattacacatttgcatctggttctccagataacataaagcagtggaaattc
cctgatggaagtttcattcaaaatctttccggtcataatgctattattaacacattgacg
gtaaattctgatggagtgcttgtatctggagctgacaatggcaccatgcatctttgggac
tggagaactggctacaattttcagagagttcacgcagctgtgcaacctgggtctttggac
agtgaatcaggaatatttgcttgtgcttttgatcagtctgaaagtcgattactaacagct
gaagctgataaaaccattaaagtatacagagaggatgacacagccacagaagaaactcat
ccagtcagctggaaaccagaaattatcaagagaaagagattttaa

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