Homo sapiens (human): 54106 Help Entry 54106             CDS       T01001                                  Symbol TLR9, CD289 Name (RefSeq) toll like receptor 9   KO K10161   toll-like receptor 9 Organism hsa  Homo sapiens (human) Pathway hsa04620   Toll-like receptor signaling pathway hsa05132   Salmonella infection hsa05142   Chagas disease hsa05143   African trypanosomiasis hsa05144   Malaria hsa05152   Tuberculosis hsa05162   Measles hsa05168   Herpes simplex virus 1 infection hsa05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Network nt06169  Measles virus (MV) nt06517  TLR signaling   Element N00690   TLR7/9-IRF7 signaling pathway N01543   TLR7/8/9-IRF5 signaling pathway Drug target Agatolimod (DG01428):  D08841 D08842 Cobitolimod (DG03213):  D12275 D12276 Nelitolimod (DG03303):  D12855 D12856 Tilsotolimod (DG03024):  D11504 D11505 Vidutolimod:  D12936 Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     54106 (TLR9)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     54106 (TLR9)   09172 Infectious disease: viral    05162 Measles     54106 (TLR9)    05168 Herpes simplex virus 1 infection     54106 (TLR9)   09171 Infectious disease: bacterial    05132 Salmonella infection     54106 (TLR9)    05152 Tuberculosis     54106 (TLR9)   09174 Infectious disease: parasitic    05144 Malaria     54106 (TLR9)    05142 Chagas disease     54106 (TLR9)    05143 African trypanosomiasis     54106 (TLR9)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:hsa04054]     54106 (TLR9)    04090 CD molecules [BR:hsa04090]     54106 (TLR9) Pattern recognition receptors [BR:hsa04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    54106 (TLR9) CD molecules [BR:hsa04090]  Proteins   54106 (TLR9) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 LRR_4 LRR_12 LRR_14 LRR_6 LRR_Zer-1 TIR FNIP TIR_2 Motif Other DBs NCBI-GeneID:  54106 NCBI-ProteinID:  NP_059138 OMIM:  605474 HGNC:  15633 Ensembl:  ENSG00000239732 UniProt:  Q9NR96 Structure PDBPDBj LinkDB All DBs Position 3:complement(52221080..52225645) Genome browser AA seq 1032 aa AA seqDB search MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAA PRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFL AVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYY KNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDL ANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLN ASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSF GSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYV DLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLS RNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHS FTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSL RALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRL RDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGF FSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAA VPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCG WDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRG RWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLE DRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHF YNRNFCQGPTAE NT seq 3099 nt NT seq  +upstreamnt  +downstreamnt atgggtttctgccgcagcgccctgcacccgctgtctctcctggtgcaggccatcatgctg gccatgaccctggccctgggtaccttgcctgccttcctaccctgtgagctccagccccac ggcctggtgaactgcaactggctgttcctgaagtctgtgccccacttctccatggcagca ccccgtggcaatgtcaccagcctttccttgtcctccaaccgcatccaccacctccatgat tctgactttgcccacctgcccagcctgcggcatctcaacctcaagtggaactgcccgccg gttggcctcagccccatgcacttcccctgccacatgaccatcgagcccagcaccttcttg gctgtgcccaccctggaagagctaaacctgagctacaacaacatcatgactgtgcctgcg ctgcccaaatccctcatatccctgtccctcagccataccaacatcctgatgctagactct gccagcctcgccggcctgcatgccctgcgcttcctattcatggacggcaactgttattac aagaacccctgcaggcaggcactggaggtggccccgggtgccctccttggcctgggcaac ctcacccacctgtcactcaagtacaacaacctcactgtggtgccccgcaacctgccttcc agcctggagtatctgctgttgtcctacaaccgcatcgtcaaactggcgcctgaggacctg gccaatctgaccgccctgcgtgtgctcgatgtgggcggaaattgccgccgctgcgaccac gctcccaacccctgcatggagtgccctcgtcacttcccccagctacatcccgataccttc agccacctgagccgtcttgaaggcctggtgttgaaggacagttctctctcctggctgaat gccagttggttccgtgggctgggaaacctccgagtgctggacctgagtgagaacttcctc tacaaatgcatcactaaaaccaaggccttccagggcctaacacagctgcgcaagcttaac ctgtccttcaattaccaaaagagggtgtcctttgcccacctgtctctggccccttccttc gggagcctggtcgccctgaaggagctggacatgcacggcatcttcttccgctcactcgat gagaccacgctccggccactggcccgcctgcccatgctccagactctgcgtctgcagatg aacttcatcaaccaggcccagctcggcatcttcagggccttccctggcctgcgctacgtg gacctgtcggacaaccgcatcagcggagcttcggagctgacagccaccatgggggaggca gatggaggggagaaggtctggctgcagcctggggaccttgctccggccccagtggacact cccagctctgaagacttcaggcccaactgcagcaccctcaacttcaccttggatctgtca cggaacaacctggtgaccgtgcagccggagatgtttgcccagctctcgcacctgcagtgc ctgcgcctgagccacaactgcatctcgcaggcagtcaatggctcccagttcctgccgctg accggtctgcaggtgctagacctgtcccacaataagctggacctctaccacgagcactca ttcacggagctaccgcgactggaggccctggacctcagctacaacagccagccctttggc atgcagggcgtgggccacaacttcagcttcgtggctcacctgcgcaccctgcgccacctc agcctggcccacaacaacatccacagccaagtgtcccagcagctctgcagtacgtcgctg cgggccctggacttcagcggcaatgcactgggccatatgtgggccgagggagacctctat ctgcacttcttccaaggcctgagcggtttgatctggctggacttgtcccagaaccgcctg cacaccctcctgccccaaaccctgcgcaacctccccaagagcctacaggtgctgcgtctc cgtgacaattacctggccttctttaagtggtggagcctccacttcctgcccaaactggaa gtcctcgacctggcaggaaaccagctgaaggccctgaccaatggcagcctgcctgctggc acccggctccggaggctggatgtcagctgcaacagcatcagcttcgtggcccccggcttc ttttccaaggccaaggagctgcgagagctcaaccttagcgccaacgccctcaagacagtg gaccactcctggtttgggcccctggcgagtgccctgcaaatactagatgtaagcgccaac cctctgcactgcgcctgtggggcggcctttatggacttcctgctggaggtgcaggctgcc gtgcccggtctgcccagccgggtgaagtgtggcagtccgggccagctccagggcctcagc atctttgcacaggacctgcgcctctgcctggatgaggccctctcctgggactgtttcgcc ctctcgctgctggctgtggctctgggcctgggtgtgcccatgctgcatcacctctgtggc tgggacctctggtactgcttccacctgtgcctggcctggcttccctggcgggggcggcaa agtgggcgagatgaggatgccctgccctacgatgccttcgtggtcttcgacaaaacgcag agcgcagtggcagactgggtgtacaacgagcttcgggggcagctggaggagtgccgtggg cgctgggcactccgcctgtgcctggaggaacgcgactggctgcctggcaaaaccctcttt gagaacctgtgggcctcggtctatggcagccgcaagacgctgtttgtgctggcccacacg gaccgggtcagtggtctcttgcgcgccagcttcctgctggcccagcagcgcctgctggag gaccgcaaggacgtcgtggtgctggtgatcctgagccctgacggccgccgctcccgctac gtgcggctgcgccagcgcctctgccgccagagtgtcctcctctggccccaccagcccagt ggtcagcgcagcttctgggcccagctgggcatggccctgaccagggacaaccaccacttc tataaccggaacttctgccagggacccacggccgaatag

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