Homo sapiens (human): 54657
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Entry
54657 CDS
T01001
Symbol
UGT1A4, GNT1, HUG-BR2, UDPGT, UDPGT_1-4, UGT-1A, UGT-1D, UGT1, UGT1-01, UGT1-04, UGT1.1, UGT1.4, UGT1A, UGT1A1, UGT1A4S, UGT1D, hUG-BR1
Name
(RefSeq) UDP glucuronosyltransferase family 1 member A4
KO
K00699
glucuronosyltransferase [EC:
2.4.1.17
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00040
Pentose and glucuronate interconversions
hsa00053
Ascorbate and aldarate metabolism
hsa00140
Steroid hormone biosynthesis
hsa00830
Retinol metabolism
hsa00860
Porphyrin metabolism
hsa00980
Metabolism of xenobiotics by cytochrome P450
hsa00982
Drug metabolism - cytochrome P450
hsa00983
Drug metabolism - other enzymes
hsa01100
Metabolic pathways
hsa01240
Biosynthesis of cofactors
hsa04976
Bile secretion
hsa05204
Chemical carcinogenesis - DNA adducts
hsa05207
Chemical carcinogenesis - receptor activation
Module
hsa_M00014
Glucuronate pathway (uronate pathway)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00040 Pentose and glucuronate interconversions
54657 (UGT1A4)
00053 Ascorbate and aldarate metabolism
54657 (UGT1A4)
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
54657 (UGT1A4)
09108 Metabolism of cofactors and vitamins
00830 Retinol metabolism
54657 (UGT1A4)
00860 Porphyrin metabolism
54657 (UGT1A4)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
54657 (UGT1A4)
00982 Drug metabolism - cytochrome P450
54657 (UGT1A4)
00983 Drug metabolism - other enzymes
54657 (UGT1A4)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
54657 (UGT1A4)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
54657 (UGT1A4)
05207 Chemical carcinogenesis - receptor activation
54657 (UGT1A4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:
hsa01003
]
54657 (UGT1A4)
Enzymes [BR:
hsa01000
]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.17 glucuronosyltransferase
54657 (UGT1A4)
Glycosyltransferases [BR:
hsa01003
]
Others
Hydrophobic molecule
54657 (UGT1A4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
UDPGT
EryCIII-like_C
Glyco_tran_28_C
Glyco_transf_4
Motif
Other DBs
NCBI-GeneID:
54657
NCBI-ProteinID:
NP_009051
OMIM:
606429
HGNC:
12536
Ensembl:
ENSG00000244474
UniProt:
P22310
LinkDB
All DBs
Position
2:233718736..233773300
Genome browser
AA seq
534 aa
AA seq
DB search
MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
NT seq
1605 nt
NT seq
+upstream
nt +downstream
nt
atggccagaggactccaggttcccctgccgcggctggccacaggactgctgctcctcctc
agtgtccagccctgggctgagagtggaaaggtgttggtggtgcccactgatggcagcccc
tggctcagcatgcgggaggccttgcgggagctccatgccagaggccaccaggcggtggtc
ctcaccccagaggtgaatatgcacatcaaagaagagaaatttttcaccctgacagcctat
gctgttccatggacccagaaggaatttgatcgcgttacgctgggctacactcaagggttc
tttgaaacagaacatcttctgaagagatattctagaagtatggcaattatgaacaatgta
tctttggcccttcataggtgttgtgtggagctactgcataatgaggccctgatcaggcac
ctgaatgctacttcctttgatgtggttttaacagaccccgttaacctctgtggggcggtg
ctggctaagtacctgtcgattcctgctgtgtttttttggaggtacattccatgtgactta
gactttaagggcacacagtgtccaaatccttcctcctatattcctaagttactaacgacc
aattcagaccacatgacattcctgcaaagggtcaagaacatgctctaccctctggccctg
tcctacatttgccatactttttctgccccttatgcaagtcttgcctctgagctttttcag
agagaggtgtcagtggtggatcttgtcagctatgcatccgtgtggctgttccgaggggac
tttgtgatggactaccccaggccgatcatgcccaacatggtcttcattgggggcatcaac
tgtgccaacgggaagccactatctcaggaatttgaagcctacattaatgcttctggagaa
catggaattgtggttttctctttgggatcaatggtctcagaaattccagagaagaaagct
atggcaattgctgatgctttgggcaaaatccctcagacagtcctgtggcggtacactgga
acccgaccatcgaatcttgcgaacaacacgatacttgttaagtggctaccccaaaacgat
ctgcttggtcacccgatgacccgtgcctttatcacccatgctggttcccatggtgtttat
gaaagcatatgcaatggcgttcccatggtgatgatgcccttgtttggtgatcagatggac
aatgcaaagcgcatggagactaagggagctggagtgaccctgaatgttctggaaatgact
tctgaagatttagaaaatgctctaaaagcagtcatcaatgacaaaagttacaaggagaac
atcatgcgcctctccagccttcacaaggaccgcccggtggagccgctggacctggccgtg
ttctgggtggagtttgtgatgaggcacaagggcgcgccacacctgcgccccgcagcccac
gacctcacctggtaccagtaccattccttggacgtgattggtttcctcttggccgtcgtg
ctgacagtggccttcatcacctttaaatgttgtgcttatggctaccggaaatgcttgggg
aaaaaagggcgagttaagaaagcccacaaatccaagacccattga
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