Homo sapiens (human): 55240
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Entry
55240 CDS
T01001
Symbol
STEAP3, AHMIO2, STMP3, TSAP6, dudlin-2, dudulin-2, pHyde
Name
(RefSeq) STEAP3 metalloreductase
KO
K10142
metalloreductase STEAP3 [EC:1.16.1.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04115
p53 signaling pathway
hsa04216
Ferroptosis
Network
nt06525
Ferroptosis
Element
N01587
Fe-TF transport
Disease
H01196
Hypochromic microcytic anemia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
55240 (STEAP3)
04115 p53 signaling pathway
55240 (STEAP3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
55240 (STEAP3)
Membrane trafficking [BR:
hsa04131
]
Exocytosis
Others
Others
55240 (STEAP3)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
F420_oxidored
Ferric_reduct
NAD_binding_2
Shikimate_DH
2-Hacid_dh_C
IlvN
Leg1
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
55240
NCBI-ProteinID:
NP_001008410
OMIM:
609671
HGNC:
24592
Ensembl:
ENSG00000115107
UniProt:
Q658P3
Structure
PDB
LinkDB
All DBs
Position
2:119223834..119265652
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AA seq
488 aa
AA seq
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MPEEMDKPLISLHLVDSDSSLAKVPDEAPKVGILGSGDFARSLATRLVGSGFKVVVGSRN
PKRTARLFPSAAQVTFQEEAVSSPEVIFVAVFREHYSSLCSLSDQLAGKILVDVSNPTEQ
EHLQHRESNAEYLASLFPTCTVVKAFNVISAWTLQAGPRDGNRQVPICGDQPEAKRAVSE
MALAMGFMPVDMGSLASAWEVEAMPLRLLPAWKVPTLLALGLFVCFYAYNFVRDVLQPYV
QESQNKFFKLPVSVVNTTLPCVAYVLLSLVYLPGVLAAALQLRRGTKYQRFPDWLDHWLQ
HRKQIGLLSFFCAALHALYSFCLPLRRAHRYDLVNLAVKQVLANKSHLWVEEEVWRMEIY
LSLGVLALGTLSLLAVTSLPSIANSLNWREFSFVQSSLGFVALVLSTLHTLTYGWTRAFE
ESRYKFYLPPTFTLTLLVPCVVILAKALFLLPCISRRLARIRRGWERESTIKFTLPTDHA
LAEKTSHV
NT seq
1467 nt
NT seq
+upstream
nt +downstream
nt
atgccagaagagatggacaagccactgatcagcctccacctggtggacagcgatagtagc
cttgccaaggtccccgatgaggcccccaaagtgggcatcctgggtagcggggactttgcc
cgctccctggccacacgcctggtgggctctggcttcaaagtggtggtggggagccgcaac
cccaaacgcacagccaggctgtttccctcagcggcccaagtgactttccaagaggaggca
gtgagctccccggaggtcatctttgtggctgtgttccgggagcactactcttcactgtgc
agtctcagtgaccagctggcgggcaagatcctggtggatgtgagcaaccctacagagcaa
gagcaccttcagcatcgtgagtccaatgctgagtacctggcctccctcttccccacttgc
acagtggtcaaggccttcaatgtcatctctgcctggaccctgcaggctggcccaagggat
ggtaacaggcaggtgcccatctgcggtgaccagccagaagccaagcgtgctgtctcggag
atggcgctcgccatgggcttcatgcccgtggacatgggatccctggcgtcagcctgggag
gtggaggccatgcccctgcgcctcctcccggcctggaaggtgcccaccctgctggccctg
gggctcttcgtctgcttctatgcctacaacttcgtccgggacgttctgcagccctatgtg
caggaaagccagaacaagttcttcaagctgcccgtgtccgtggtcaacaccacactgccg
tgcgtggcctacgtgctgctgtcactcgtgtacttgcccggcgtgctggcggctgccctg
cagctgcggcgcggcaccaagtaccagcgcttccccgactggctggaccactggctacag
caccgcaagcagatcgggctgctcagcttcttctgcgccgccctgcacgccctctacagc
ttctgcttgccgctgcgccgcgcccaccgctacgacctggtcaacctggcagtcaagcag
gtcttggccaacaagagccacctctgggtggaggaggaggtctggcggatggagatctac
ctctccctgggagtgctggccctcggcacgttgtccctgctggccgtgacctcactgccg
tccattgcaaactcgctcaactggagggagttcagcttcgttcagtcctcactgggcttt
gtggccctcgtgctgagcacactgcacacgctcacctacggctggacccgcgccttcgag
gagagccgctacaagttctacctgcctcccaccttcacgctcacgctgctggtgccctgc
gtcgtcatcctggccaaagccctgtttctcctgccctgcatcagccgcagactcgccagg
atccggagaggctgggagagggagagcaccatcaagttcacgctgcccacagaccacgcc
ctggccgagaagacgagccacgtatga
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