KEGG T01001: 55304

Homo sapiens (human): 55304

Entry

55304             CDS       T01001

Symbol

SPTLC3, C20orf38, LCB_3, LCB2B, LCB3, SPT_3, SPT3, SPTLC2L, dJ718P11, dJ718P11.1, hLCB2b

Name

(RefSeq) serine palmitoyltransferase long chain base subunit 3

K00654

serine palmitoyltransferase [EC:2.3.1.50]

Organism

hsa Homo sapiens (human)

Pathway

hsa00600

Sphingolipid metabolism

hsa01100

Metabolic pathways

hsa04071

Sphingolipid signaling pathway

hsa04382

Cornified envelope formation

Module

hsa_M00094

Ceramide biosynthesis

hsa_M00099

Sphingosine biosynthesis

Network

nt06545 Cornified envelope formation

Element

N01926

Sphinganine synthesis

Brite

KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    55304 (SPTLC3)
09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    55304 (SPTLC3)
09150 Organismal Systems
  09158 Development and regeneration
   04382 Cornified envelope formation
    55304 (SPTLC3)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    55304 (SPTLC3)
Enzymes [BR:hsa01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.50  serine C-palmitoyltransferase
     55304 (SPTLC3)
Amino acid related enzymes [BR:hsa01007]
Aminotransferase (transaminase)
  Class II
   55304 (SPTLC3)

SSDB

Motif

Pfam:

Aminotran_1_2 Aminotran_5 Beta_elim_lyase Cys_Met_Meta_PP

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

LinkDB

Position

20:13008972..13169103

AA seq 552 aa
MANPGGGAVCNGKLHNHKKQSNGSQSRNCTKNGIVKEAQQNGKPHFYDKLIVESFEEAPL
HVMVFTYMGYGIGTLFGYLRDFLRNWGIEKCNAAVERKEQKDFVPLYQDFENFYTRNLYM
RIRDNWNRPICSAPGPLFDLMERVSDDYNWTFRFTGRVIKDVINMGSYNFLGLAAKYDES
MRTIKDVLEVYGTGVASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPA
LVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDAVIYGQPRTRRAWK
KILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGVTEFFGLDPH
EVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAEQIIRSLKLIMG
LDGTTQGLQRVQQLAKNTRYFRQRLQEMGFIIYGNENASVVPLLLYMPGKVAAFARHMLE
KKIGVVVVGFPATPLAEARARFCVSAAHTREMLDTVLEALDEMGDLLQLKYSRHKKSARP
ELYDETSFELED

NT seq 1659 nt +upstreamnt +downstreamnt
atggctaaccctggaggtggtgctgtttgcaacgggaaacttcacaatcacaagaaacag
agcaatggctcacaaagcagaaactgcacaaagaatggaatagtgaaggaagcccagcaa
aatgggaagccacatttttatgataagctcattgttgaatcgtttgaggaagcacccctt
catgttatggttttcacttacatgggatatggaattggaaccctgtttggctatctcaga
gactttttaagaaactggggaatagaaaaatgcaacgcagctgtggaaagaaaagaacaa
aaagattttgtgccactgtatcaagactttgaaaatttttatacaagaaacctttacatg
cgaatcagagacaactggaaccggcccatctgcagtgccccagggcctctgtttgatttg
atggagagggtatcagacgactataactggacgtttaggtttactggaagagtcatcaaa
gatgtcatcaacatgggctcctataacttccttggtcttgcagccaagtatgatgagtct
atgaggacaataaaggatgttttagaggtgtatggcacaggcgtggccagcaccaggcat
gaaatgggcaccttggataagcacaaggagttggaggaccttgtggctaagttcctgaat
gtggaagcagctatggtctttgggatgggattcgcaactaactcaatgaatatcccagca
ttagttggaaagggatgcctcattttaagtgatgagttaaaccacacatcgcttgtgctt
ggggcccgactctcaggtgcaaccataagaatcttcaaacacaacaacacacaaagccta
gagaagctcctgagagatgctgtcatctatggccagcctcgaacccgcagagcttggaaa
aagattctcatcctggtggagggtgtctacagcatggaaggttccatcgtgcatctgccc
cagatcatagctctaaagaagaaatacaaggcttacctctacatagatgaagctcacagt
attggggccgtgggcccaaccggccggggtgtcacggagttctttggactagaccctcat
gaagttgatgtgctcatgggcacattcaccaaaagttttggagcttcaggaggttacata
gctggaaggaaggacctcgtggattatttacgggttcactcgcatagtgctgtttatgct
tcatccatgagcccaccgatagcagagcaaatcatcagatcactaaaacttatcatggga
ctggatgggaccactcaagggctgcagagagtacagcaacttgcgaaaaacacaagatac
ttcagacaaagactgcaggaaatgggattcattatctatggcaatgagaatgcttctgtt
gttcctctgcttctttatatgcctggtaaagtagcggcttttgcaaggcatatgctagag
aaaaaaattggagtggtggtcgtgggatttccagccactcccctcgcagaagctcgggct
cggttttgtgtttcagcggcacatacccgggagatgttagacacggttttagaagctctt
gatgaaatgggtgatctcttgcaactgaaatattcccggcacaagaagtcagcacgtcct
gagctctatgatgagacgagctttgaactcgaagattaa

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